Abstract: There are described phthalocyanine derivates, the pharmaceutical compositions and the medical devices that contain them, possibly in combination with chelating agents, such as EDTA, useful for treating, by means of photodynamic therapy, diseases characterised by cellular hyperproliferation, microbial infections caused by Gram? bacteria, Gram+ bacteria and fungi, and for treating various types of infected and non-infected ulcers.
August 6, 2012
June 12, 2014
MOLTENI THERAPEUTICS S.R.L.
Donata Dei, Gabrio Roncucci, Gianluca Soldaini, Daniele Nistri, Giacomo Chiti, Moira Municchi, Lia Fantetti, Francesco Giuliani
Abstract: Self-sterilising products, and in particular novel products comprising phthalocyanine derivatives bound to polymers, a process for the preparation of said products and their use for preparing self-sterilising industrial and medical articles or devices, are described.
Abstract: The present invention relates to pharmaceutical compositions comprising metal phthalocyanine analogues of formula (I) and metal chelating compounds having a good bioavailability and enhanced photoinactivation properties against Gram negative bacteria; and to their use for in vivolex vivo applications, such as blood and blood derivatives sterilization.
April 17, 2003
Date of Patent:
March 4, 2014
Molteni Therapeutics S.r.l.
Gabrio Roncucci, Donata Dei, Giacomo Chiti, Lia Fantetti, Francesco Giuliani, Giulio Jori, Gian Maria Rossolini