Patents Assigned to Momenta Pharmaceuticals, Inc.
  • Publication number: 20140051830
    Abstract: The present disclosure provides methods for manufacturing or producing glatiramer acetate having a Mp of 5000-9000 Da.
    Type: Application
    Filed: October 28, 2013
    Publication date: February 20, 2014
    Applicant: Momenta Pharmaceuticals, Inc.
    Inventors: Mani S. Iyer, Harper Kaminski
  • Publication number: 20140045204
    Abstract: Methods of analyzing glatiramer acetate (GA) or a polymeric precursor thereof are provided. The methods can include determining a level of one or more diethylamide-modified amino acids in a sample comprising GA or a polymeric precursor thereof, and selecting at least a portion of the sample based on the assessment of the one or more diethylamide-modified amino acids in the sample.
    Type: Application
    Filed: September 6, 2013
    Publication date: February 13, 2014
    Applicant: Momenta Pharmaceuticals, Inc.
    Inventors: Cuihua Liu, Shiming Dong, Xiao-Jin Xu, Jonathan C. Lansing, Yanjie Jiang
  • Publication number: 20140046024
    Abstract: Methods of analyzing glatiramer acetate (GA) or a polymeric precursor thereof are provided. The methods can include determining a level of one or more diethylamide-modified amino acids in a sample comprising GA or a polymeric precursor thereof, and selecting at least a portion of the sample based on the assessment of the one or more diethylamide-modified amino acids in the sample.
    Type: Application
    Filed: December 3, 2012
    Publication date: February 13, 2014
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Cuihua Liu, Shiming Dong, Xiao-Jin Xu, Jonathan C. Lansing, Yanjie Jiang
  • Publication number: 20140045212
    Abstract: The present invention provides methods of evaluating CHO cells.
    Type: Application
    Filed: October 17, 2013
    Publication date: February 13, 2014
    Applicant: Momenta Pharmaceuticals, Inc.
    Inventors: Carlos J. Bosques, Jennifer Murphy, Hetal Sarvaiya, Nathaniel Washburn, Cuihua Liu, Xiao-Jin Xu
  • Publication number: 20140045740
    Abstract: The present disclosure relates to methods for assessing molecular weight characteristics of glatiramer acetate using SEC-MALS.
    Type: Application
    Filed: August 12, 2013
    Publication date: February 13, 2014
    Applicant: Momenta Pharmaceuticals, Inc.
    Inventors: Joseph Glajch, Ying Li
  • Publication number: 20140031315
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 30, 2014
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • Publication number: 20140024602
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 23, 2014
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • Patent number: 8614314
    Abstract: Described are oligosaccharides having a protecting group at two, a plurality, a majority of, or each position in the oligosaccharide which is amenable to derivatization. Collections, libraries and methods of making and using such oligosaccharides are also described.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: December 24, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Roy Sucharita, Takashi Kei Kishimoto, Ganesh Venkataraman
  • Patent number: 8609372
    Abstract: A glycosyl transferase from Chinese hamster and related methods are described.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: December 17, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventor: James W. Meador, III
  • Patent number: 8609632
    Abstract: Preparations of low molecular weight heparins (LMWHs) having improved properties, e.g., properties that provide a clinical advantage, are provided herein. Methods of making and using such preparations as well as methods of analyzing starting materials, processing, intermediates and final products in the production of such LMWH preparations are provided.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: December 17, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Zachary Shriver, Mallikarjun Sundaram, Ganesh Venkataraman, Pat Oliver-Shaffer, Yiming Yao, Zainab Sirajbhai Mamuwala, Ian David Fier, Yiwei Qi, Ishan Capila, Nur Sibel Gunay, Daniela Beccati, Cuihua Liu, Corinne Bauer, Ying Li
  • Patent number: 8597957
    Abstract: The disclosure features methods of analyzing preparations of heparin, and materials derived from heparin using strong anion exchange high performance liquid chromatography (SAX-HPLC).
    Type: Grant
    Filed: December 12, 2012
    Date of Patent: December 3, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: David Schrier, Nur S. Gunay, Megan Sucato, Stephen Smith, Zachary Shriver
  • Patent number: 8592142
    Abstract: Methods for analyzing, selecting, characterizing or classifying compositions of a co-polymer, e.g., glatiramer acetate are described. The methods entail analysis of pyro-glutamate in the composition, and, in some methods, comparing the amount of pyro-glutamate present in a composition to a reference standard.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: November 26, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Xiangping Zhu, Zachary Shriver, Yanjie Jiang, Corinne Bauer, James Eric Anderson, Peter James Ahern
  • Patent number: 8592393
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: November 26, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • Patent number: 8586356
    Abstract: The present invention provides methods of evaluating CHO cells.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: November 19, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Carlos Bosques, Jennifer Murphy, Hetal Sarvaiya, Nathaniel Washburn, Cuihua Liu, Xiao-Jin Xu
  • Patent number: 8575198
    Abstract: The present disclosure provides methods for manufacturing or producing glatiramer acetate having a Mp of 5000-9000 Da.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: November 5, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Mani S. Iyer, Harper Kaminski
  • Patent number: 8569262
    Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: October 29, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventors: Mallikarjun Sundaram, Takashi Kei Kishimoto, Sucharita Roy
  • Publication number: 20130231255
    Abstract: Methods and compositions related to high mannose glycans are described.
    Type: Application
    Filed: April 7, 2011
    Publication date: September 5, 2013
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: Brian Edward Collins, Jay Duffner, Carlos J. Bosques, Dorota A. Bulik, James Myette, James Meador
  • Publication number: 20130210054
    Abstract: The present disclosure relates to polarized type 2 T helper (Th2) cells and methods for using such cells in the assessment of antigenic compositions.
    Type: Application
    Filed: November 19, 2012
    Publication date: August 15, 2013
    Applicant: Momenta Pharmaceuticals, Inc.
    Inventor: Momenta Pharmaceuticals, Inc.
  • Publication number: 20130184180
    Abstract: The present disclosure provides methods for analyzing structure and/or composition of N-glycans. Such methods often involve digestion of N-glycans with multiple exoglycosidases. In some embodiments, N-glycans are digested with multiple exoglycosidases simultaneously. In some embodiments, N-glycans are digested with multiple exoglycosidases sequentially. In some embodiments, methods in accordance with the present disclosure involve comparison of cleavage products of N-glycans that have been digested with multiple exoglycosidases simultaneously to N-glycans that have been digested with multiple exoglycosidases sequentially.
    Type: Application
    Filed: December 19, 2012
    Publication date: July 18, 2013
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventor: Momenta Pharmaceuticals, Inc.
  • Publication number: 20130183254
    Abstract: Methods and compositions related to promoting hair growth are described.
    Type: Application
    Filed: June 15, 2011
    Publication date: July 18, 2013
    Applicant: MOMENTA PHARMACEUTICALS, INC.
    Inventors: He Zhou, Edward Cochran