Patents Assigned to Mycogen Plant Science, Inc.
  • Patent number: 7214861
    Abstract: A plant promoter is provided comprising the regulatory region of a legume Enod2 gene, a gene expressed in nodule tissue of legumes in the early stages of nodulation. The promoter operates to express foreign genes under its control in developing nodules. The sequence of two soybean Enod2 genes with their regulatory regions is provided.
    Type: Grant
    Filed: January 2, 2004
    Date of Patent: May 8, 2007
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Henk J. Franssen, Anton H. Blsseling
  • Patent number: 6943282
    Abstract: A method for expressing insecticidal protein structural genes in plant genomes is provided. In the preferred embodiments this invention comprises placing a structural gene for the Bacillus thuringiensis crystal protein under control of a plant or a T-DNA promoter and ahead of a polyadenylation site followed by insertion of said promoter/structural gene combination into a plant genome by utilizing an Agrobacterium tumefaciens Ti plasmid-based transformation system. The modified Ti plasmid is then used to transform recipient plant cells. Also provided are the plants and tissues produced by this method and bacterial strains, plasmids, and vectors useful for execution of this invention.
    Type: Grant
    Filed: June 10, 1991
    Date of Patent: September 13, 2005
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Michael J. Adang, John D. Kemp
  • Patent number: 6914176
    Abstract: Disclosed herein is a subgroup of corn lines comprised of plants that produce seeds having low saturated fatty acid content. The plants disclosed herein can be used to produce low saturated corn material predictably, via conventional methods. Further, the plants disclosed herein can be used to produce commercially acceptable hybrids having lower saturated fat content.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: July 5, 2005
    Assignee: Mycogen Plant Science, Inc
    Inventor: Bruce Nagel
  • Patent number: 6444879
    Abstract: The present invention provides a novel Brassica napus oleifera annua variety, an agronomically superior high oleic canola variety having a unique fatty acid profile, designated “1709”. Also provided in the present invention are seeds of canola variety 1709, plants produced from seeds of 1709, and tissue cultures of regenerable cells of the canola plant grown from 1709 seed.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: September 3, 2002
    Assignee: Mycogen Plant Science, Inc.
    Inventor: John Lawrence Sernyk
  • Patent number: 6376234
    Abstract: The present invention relates to a novel method of inserting viral DNA, which optionally may contain cargo-DNA, into plants or viable parts thereof, but preferably into plants of the monocotyledon class, and most preferably into plants of the family Gramineae, using suitable transfer microorganisms. Further comprised by the invention are recombinant DNA, plasmid and vector molecules suitably adapted to the specific conditions of the process according to the invention and the transgenic plant products obtainable in accordance with the said process.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: April 23, 2002
    Assignees: Ciba-Geigy, Mycogen Plant Science, Inc.
    Inventors: Nigel Harry Grimsley, Barbara Hohn, Thomas Hohn, Jeffrey William Davies, Margaret Irene Boulton
  • Patent number: 6251656
    Abstract: The Bacillus thuringiensis var. kurstaki HD-73 crystal protein gene was cloned into pBR322. E. coli cells harboring this recombinant plasmid produced a 130 kD protoxin that was toxic to Manduca sexta (tobacco hornworm) larvae. Plasmids having the 3′-end of the protoxin gene deleted where also constructed. E. coli cells harboring these deleted plasmids produced an active, soluble 68 kD toxin, provided that the 3′-deletion had not removed sequences encoding the 68 kD toxin. The invention provides methods to produce 68 kD toxin protein by constructing partial protoxin genes encoding the toxin followed by expression of the genes in living cells. Useful plasmids and cells are also provided.
    Type: Grant
    Filed: October 21, 1999
    Date of Patent: June 26, 2001
    Assignee: Mycogen Plant Science, Inc.
    Inventor: Michael J. Adang
  • Patent number: 6229004
    Abstract: The Bacillus thuringiensis var. kurstaki HD-73 crystal protein gene was cloned into pBR322. E. coli cells harboring this recombinant plasmid produced a 130 kD protoxin that was toxic to Manduca sexta (tobacco hornworm) larvae. Plasmids having the 3′-end of the protoxin gene deleted where also constructed. E. coli cells harboring these deleted plasmids produced an active, soluble 68 kD toxin, provided that the 3′-deletion had not removed sequences encoding the 68 kD toxin. The invention provides methods to produce 68 kD toxin protein by constructing partial protoxin genes encoding the toxin followed by expression of the genes in living cells. Useful plasmids and cells are also provided.
    Type: Grant
    Filed: July 10, 2000
    Date of Patent: May 8, 2001
    Assignee: Mycogen Plant Science, Inc.
    Inventor: Michael J. Adang
  • Patent number: 6114138
    Abstract: The Bacillus thuringiensis var. kurstaki HD-73 crystal protein gene was cloned into pBR322. E. coli cells harboring this recombinant plasmid produced a 130 kD protoxin that was toxic to Manduca sexta (tobacco hornworm) larvae. Plasmids having the 3'-end of the protoxin gene deleted where also constructed. E. coli cells harboring these deleted plasmids produced an active, soluble 68 kD toxin, provided that the 3'-deletion had not removed sequences encoding the 68 kD toxin. The invention provides methods to produce 68 kD toxin protein by constructing partial protoxin genes encoding the toxin followed by expression of the genes in living cells. Useful plasmids and cells are also provided.
    Type: Grant
    Filed: June 4, 1984
    Date of Patent: September 5, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventor: Michael J. Adang
  • Patent number: 6111070
    Abstract: The sequence of the T-DNA of the octopine-type Ti plasmid found in Agrobacterium tumefaciens ATCC 15955 is disclosed. Fourteen open reading frames bounded by eukaryotic promoters, ribosome binding sites, and polyadenylation sites were found. The use of promoters and polyadenylation sites from pTi15955 to control expression of foreign structural genes is taught, using as examples the structural genes for the Phaseolus vulgaris storage protein phaseolin, P. vulgaris lectin, thaumatin, and Bacillus thuringiensis crystal protein. Vectors useful for manipulation of sequences of the structural genes and T-DNA are also provided.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: August 29, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventors: John D. Kemp, Richard F. Barker
  • Patent number: 6090627
    Abstract: The sequence of the T-DNA of the octopine-type Ti plasmid found in Agrobacterium tumefaciens ATCC 15955 is disclosed. Fourteen open reading frames bounded by eukaryotic promoters, ribosome binding sites, and polyadenylation sites were found. The use of promoters and polyadenylation sites from pTi15955 to control expression of foreign structural genes is taught, using as examples the structural genes for the Phaseolus vulgaris storage protein phaseolin, P. vulgaris lectin, thaumatin, and Bacillus thuringiensis crystal protein. Vectors useful for manipulation of sequences of the structural genes and T-DNA are also provided.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: July 18, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventors: John D. Kemp, Richard F. Barker, Michael J. Adang
  • Patent number: 6054574
    Abstract: A DNA segment from the upstream untranscribed region of a maize ubiquitin gene is disclosed. This ubiquitin promoter region, which comprises heat shock consensus elements, initiates and regulates the transcription of genes placed under its control. Recombinant DNA molecules are also described in which a ubiquitin promoter is combined with a plant expressible structural gene for regulated expression of the structral gene and for regulated control of expression when stressed with clevated temperatures. Such recombinant DNA molecules are introduced into plant tissue so that the promoter/stuctural gene combination is expressed.
    Type: Grant
    Filed: June 9, 1998
    Date of Patent: April 25, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Peter H. Quail, Alan H. Christensen, Howard P. Hershey, Robert A. Sharrock, Thomas D. Sullivan
  • Patent number: 6037526
    Abstract: The present invention relates to a novel method of inserting viral DNA, which optionally may contain cargo-DNA, into plants or viable parts thereof, but preferably into plants of the monocotyledon class, and most preferably into plants of the family Gramineae, using suitable transfer microorganisms. Further comprised by the invention are recombinant DNA, plasmid and vector molecules suitably adapted to the specific conditions of the process according to the invention and the transgenic plant products obtainable in accordance with the said process.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: March 14, 2000
    Assignees: Ciba-Geigy, Mycogen Plant Science, Inc.
    Inventors: Nigel Harry Grimsley, Barbara Hohn, Thomas Hohn, Jeffrey William Davies, Margaret Irene Boulton
  • Patent number: 6020190
    Abstract: A method of inducibly enhancing the constitutive expression of a DNA sequence of interest is described in which plant cells are transformed with a DNA sequence of interest that is operably joined to a plant ubiquitin regulatory region comprised of a heat shock element, a promoter, a transcription start site, an intron and a translation start site, When monocot or dicot plant cells are subjected to permissive heat shock temperatures, the level of expression of the DNA sequence of interest is enhanced.
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: February 1, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Peter H. Quail, Alan H. Christensen, Howard P. Hershey, Robert A. Sharrock, Thomas D. Sullivan
  • Patent number: 6015891
    Abstract: Synthetic Baccilus thuringiensis toxin genes designed to be expressed in plants at a level higher than naturally-occurring Bt genes are provided. These genes utilize codons preferred in highly expressed monocot or dicot proteins.
    Type: Grant
    Filed: August 29, 1996
    Date of Patent: January 18, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Michael J. Adang, Elizabeth E. Murray
  • Patent number: 6013523
    Abstract: Synthetic Baccilus thuringiensis toxin genes designed to be expressed in plants at a level higher than naturally-occurring Bt genes are provided. These genes utilize codons preferred in highly expressed monocot or dicot proteins.
    Type: Grant
    Filed: August 29, 1996
    Date of Patent: January 11, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Michael J. Adang, Elizabeth E. Murray
  • Patent number: 5846795
    Abstract: A +strand RNA viral transformation of host organisms with foreign RNA, and expression of said foreign RNA. The foreign RNA is inserted into an infective RNA viral segment containing replication elements, and allowed to infect the host organism. The invention is exemplified utiliing brome mosaic RNA modified to contain a gene coding for chloramphenicol acetyl transferase (CAT) in the transformation of barley protoplasts.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 8, 1998
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Paul G. Ahlquist, Roy C. French
  • Patent number: 5824866
    Abstract: The sequence of the T.sub.L -DNA of Ri plasmids found in Agrobacterium rhizogenes strains HRI and A4 is disclosed. Sixteen open reading frames bounded by eukaryotic promoters, ribosome binding sites, and polyadenylation sites were found, five of which were observed to be transcripted in a developmentally and phenotypically regulated manner. The use of promoters and polyadenylation sites from pRi T.sub.L -DNA to control expression of heterologous foreign structural genes is taught, using as examples the structural genes for Phaseolus vulgaris storage protein (phaseolin), P. vulgaris lectin, a sweet protein (thaumatin), and Bacillus thuringiensis crystal protein. Vectors useful for manipulation of sequences of the structural genes and T-DNA are also provided.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: October 20, 1998
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Jerry L. Slightom, David A. Tepfer
  • Patent number: 5807998
    Abstract: A protein and gene encoding it are disclosed which confer sensitivity to B. maydis T toxin and the insecticide methomyl, in cells carrying the gene and expressing the protein. Toxin sensitivity domains of the protein have been identified wherein a modification yields a toxin-insensitive product.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: September 15, 1998
    Assignees: Mycogen Plant Science, Inc., North Carolina State University
    Inventors: Charles S. Levings, III, Ralph E. Dewey, Carl J. Braun
  • Patent number: 5804439
    Abstract: A recombinant RNA virus is provided allowing encapsidation of genetically engineered viral sequences in heterologous, preferably rod-shaped coat, protein capsids. Since icosahedral viruses are limited in the amount of RNA they can carry, and rod-shaped viruses are expansible, this invention allows the size of recombinant virus RNA components to be increased (or decreased). Methods of making and using such recombinant viruses are also provided, specifically with respect to the transfection of plants to bring about genotypic and phenotypic changes.
    Type: Grant
    Filed: December 27, 1996
    Date of Patent: September 8, 1998
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Paul G. Ahlquist, Roy C. French, Robert F. Sacher
  • Patent number: 5767339
    Abstract: According to the invention, there is provided an inbred corn line designated 85857. Further provided are the plants and seeds of inbred corn line 85857, and hybrids produced using 85857 inbred line as one parent crossed with a distinct inbred corn line.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 16, 1998
    Assignee: Mycogen Plant Science, Inc.
    Inventor: Leroy McCurdy