Abstract: Erectile dysfunction in a male human patient is ameliorated by oral administration to the patient of a phosphodiesterase type 5 (PDE5) inhibitor, such as sildenafil, vardenafil, or tadalafil, and a glucocorticoid such as prednisone, prednisolone, cortisone, hydrocortisone, or methylprednisolone.

Abstract: A myocardial implant for insertion into a heart wall for trans myocardial revascularization (TMR) of the heart wall. The TMR implant provides for means to promote the formation of new blood vessels (angiogenesis), and has a flexible, elongated body that contains a cavity and openings through the flexible, elongated body from the cavity. The TMR implant includes a coaxial anchoring element integrally formed at one end for securing the TMR implant in the heart wall.

Abstract: A stent for insertion into a heart wall for Trans Myocardial Revascularization (TMR) thereof. The TMR stent provides for the delivery of blood nutrients from a heart chamber into the heart wall and has an elongated body which may contain a cavity and openings through the elongated body from the cavity. The elongated body should be in fluid communication with the heart chamber. If a cavity and openings are provided, the openings are in fluid communication with the heart chamber, the cavity and the heart wall. The TMR stent may include an anchoring element integrally formed thereon for securing the TMR stent in the heart wall.

Abstract: A delivery device for insertion of a myocardial implant into a heart wall for trans myocardial revascularization (TMR) of the heart wall. The delivery device provides for the exact placement of one or more TMR implants into a heart wall, and has an elongated, tubular body that may include spaced-apart ports and a connecting conduit. A needle point is formed at one end to pierce the heart wall, and a handle is formed at another end to manipulate the device. The delivery device may include a surrounding sheath into which the needle point and a needle assembly may be withdrawn to release the TMR implant in the heart wall, and withdraw the delivery device from a person's body. The sheath may include a locking portion for holding the TMR implant in position when releasing the implant in a heart wall.

Abstract: A stent for insertion into a heart wall for Trans Myocardial Revascularization (TMR) thereof. The TMR stent provides for the delivery of blood nutrients from a heart chamber into the heart wall and has an elongated body which may contain a cavity and openings through the elongated body from the cavity. The elongated body should be in fluid communication with the heart chamber. If a cavity and openings are provided, the openings are in fluid communication with the heart chamber, the cavity and the heart wall. The TMR stent may include an anchoring element integrally formed thereon for securing the TMR stent in the heart wall.

Abstract: A stent for insertion into a heart wall for Trans Myocardial Revascularization (TMR) thereof. The TMR stent provides for the delivery of blood nutrients from a heart chamber into the heart wall and has an elongated body which may contain a cavity and openings through the elongated body from the cavity. The elongated body should be in fluid communication with the heart chamber. If a cavity and openings are provided, the openings are in fluid communication with the heart chamber, the cavity and the heart wall. The TMR stent may include an anchoring element integrally formed thereon for securing the TMR stent in the heart wall.