Abstract: Method for the treatment of multiple sclerosis and other T cell mediated autoimmune disorders is described. The method involves administering to a subject a therapeutically effective amount of an antagonist of a receptor on a surface of a T cell which mediates contact dependent helper effector functions, for example, an anti-gp39 antibody.
June 7, 1995
Date of Patent:
November 10, 1998
Trustees of Dartmouth College, Nederlanse Organisatie Voor Teogepastnatuurwetenschappelijk Onderzoek TNO