Abstract: A carry case is provided for use by a diabetic patient. The carry case comprises a first compartment sized and shaped to contain an aerosolization apparatus, a second compartment sized and shaped to contain one or more receptacles for use in the aerosolization apparatus, and a third compartment sized and shaped to contain a glucose meter. In one version, the receptacles contain an aerosolizable pharmaceutical formulation comprising insulin. The carry case allows the patient to conveniently monitor and regulate the patient's glucose level.
Abstract: An aerosolization device comprises a housing, a container comprising a reservoir storing a pharmaceutical formulation which comprises a propellant, and a metering valve. The metering valve is in communication with the reservoir and is moveable into the container to an actuated position where a predetermined amount of the pharmaceutical formulation is released. A contact member is provided in the housing. In one version, the contact member is moveable between a first position and a second position to allow for selective actuation of the metering valve. In another version, the contact member's configuration may be changed to allow for selective actuation of the metering valve.
Abstract: An aerosolization apparatus comprises a container containing a pharmaceutical formulation, the pharmaceutical formulation comprising an active agent and a propellant. The aerosolization apparatus further comprises a metering chamber in communication with the container, the metering chamber adapted to hold a metered amount of the pharmaceutical formulation, a valve to allow the metered amount of the pharmaceutical formulation to be released from the metering chamber when the valve is actuated, and a pressurizer that applies pressure to the pharmaceutical formulation in the metering chamber while the pharmaceutical formulation is being released from the metering chamber. In one version, the metering chamber is sized so that at least 2 mg, and preferably at least 5 mg, of the active agent is be aerosolized for delivery to a user during inhalation.
Abstract: An aerosolization apparatus comprises a body defining an inlet opening, an outlet opening, and an aerosolization chamber between the inlet opening and the outlet opening. The aerosolization chamber is adapted to receive an elongated receptacle, such as a capsule, containing a pharmaceutical formulation. The elongated receptacle rotates end-over-end about an axis substantially orthogonal to an axis passing through the outlet opening when air or gas flows through the body. In another version, the elongated receptacle rotates end-over-end about an axis substantially orthogonal to an inhalation direction.