Patents Assigned to Octoplus Sciences B.V.
  • Publication number: 20110053835
    Abstract: The present invention relates to a group of peptidic compounds which have antimicrobial activity. The compounds also have affinity for toxins and especially for bacterial toxins, such as lipopolysaccharide or lipoteichoic acid. The compounds can be used to manufacture medicaments useful for the treatment of bacterial or fungal infections. The medicaments may be administered systemically or locally.
    Type: Application
    Filed: September 14, 2010
    Publication date: March 3, 2011
    Applicant: OctoPlus Sciences B.V.
    Inventors: Johannes Jakobus GROTE, Jan Wouter Drijfhout, Pieter Sicco Hiemstra, Marcel Jan Vonk, Maartje Johanna Nell, Guido Vincent Bloemberg
  • Patent number: 7468151
    Abstract: The present invention is directed to a method for purifying microparticles. These microparticles are prepared in a liquid medium and are recovered free from impurities and undesirable reaction products in a particular way. In addition, an apparatus has been claimed to carry out the method of the invention. Since the microparticles are essentially intended to carry drugs or other biologically active compounds, the entire process can be carried out aseptically.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: December 23, 2008
    Assignee: Octoplus Sciences B.V.
    Inventors: Adrianus Franciscus G. van Buitenen, Rudolf Verrijk
  • Publication number: 20080008733
    Abstract: The invention discloses a pharmaceutical composition for the controlled release of relatively toxic active compounds, in particular for bioactive proteins from the class of interferons. The composition comprises a biodegradable block copolymer constructed from poly(ethylene glycol) terephthalate (PEGT) and poly(butylene terephthalate) (PBT). The composition is provided in the form of injectable microparticles, of an injectable liquid which may have self-gelling properties, or of a solid implant. The invention further provides a pharmaceutical kit comprising the composition, methods for preparing the composition, and the pharmaceutical uses relating thereto.
    Type: Application
    Filed: July 6, 2007
    Publication date: January 10, 2008
    Applicant: OctoPlus Sciences B.V.
    Inventors: Anne Bechet, Riemke van Dijkhuizen-Radersma, Martin Stigter, Jeroen Bezemer