Patents Assigned to Ohio University/Edison Animal Biotechnolgy Center
  • Virus-resistant transgenic mice
    Patent number: 5175385
    Abstract: A transgenic mouse with enhanced viral resistance transmissible to its offspring is prepared by introduction of a gene encoding a human interferon having antiviral activity into a host mouse. The gene encodes the interferon of a different animal species and therefore its expression product is less toxic to the host at an embryonic, fetal, neonatal or junvenile stage of development. Preferably, the human beta interferon gene is introduced into the cells of a mouse.
    Type: Grant
    Filed: September 3, 1987
    Date of Patent: December 29, 1992
    Assignee: Ohio University/Edison Animal Biotechnolgy Center
    Inventors: Thomas E. Wagner, Xiao-Zhuo Chen