Abstract: A disposable set of components for an organ perfusion system comprising a fluid supply duct for supplying fluid to the organ, a fluid removal duct for removing fluid from the organ, and a surrogate organ removably connected between the fluid supply duct and the fluid removal duct so as to form a fluid circuit, so that fluid can be circulated in the circuit in preparation for connection of the organ.
Type:
Grant
Filed:
December 23, 2019
Date of Patent:
April 16, 2024
Assignee:
ORGANOX LIMITED
Inventors:
Stuart Brian William Kay, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
Abstract: An organ perfusion system comprises: a perfusion fluid circuit (16) arranged to circulate perfusion fluid through the organ; a surrogate organ (126) arranged to be connected into the circuit in place of the organ so that the circuit can circulate fluid through the surrogate organ; and organ sensing means arranged to distinguish between the presence of the organ in the circuit and the presence of the surrogate organ in the circuit. The sensing means may comprise one or more pressure sensors (136, 137, 138), or a flow meter (125). Further aspects relate to adjusting the content of at least one component, such as oxygen or a nutrient, in the perfusion fluid. Bubble detection means (113), and means (74) to measure the amount of fluid secreted by or leaked from the organ, may also be provided.
Type:
Grant
Filed:
November 8, 2016
Date of Patent:
January 3, 2023
Assignee:
Organox Limited
Inventors:
Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
Abstract: A perfusion system for the perfusion of an organ comprises a perfusion fluid circuit (16) for circulating perfusion fluid through the organ, oxygenation means (14) for adding oxygen into the perfusion fluid, and an oxygen supply arranged to supply oxygen to the oxygenation means. The oxygen supply comprises an oxygen concentrator.
Type:
Grant
Filed:
November 8, 2012
Date of Patent:
July 30, 2019
Assignee:
Organox Limited
Inventors:
Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, Leslie James Russell, Peter John Friend, Constantin C. Coussios
Abstract: An organ perfusion system comprises: a perfusion fluid circuit (16) arranged to circulate perfusion fluid through the organ; a surrogate organ (126) arranged to be connected into the circuit in place of the organ so that the circuit can circulate fluid through the surrogate organ; and organ sensing means arranged to distinguish between the presence of the organ in the circuit and the presence of the surrogate organ in the circuit. The sensing means may comprise one or more pressure sensors (136, 137, 138), or a flow meter (125). Further aspects relate to adjusting the content of at least one component, such as oxygen or a nutrient, in the perfusion fluid. Bubble detection means (113), and means (74) to measure the amount of fluid secreted by or leaked from the organ, may also be provided.
Type:
Application
Filed:
November 8, 2012
Publication date:
October 16, 2014
Applicant:
Organox Limited
Inventors:
Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, JR., David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios