Abstract: The present invention provides polymerizable biocompatible materials stabilized by amino acids or reducing salts to improve shelf life. Methods of stabilizing a polymerizable biocompatible material that inhibit auto polymerization of the material over time are also provided.
Abstract: Biocompatible bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.
Type:
Application
Filed:
December 10, 2008
Publication date:
June 18, 2009
Applicant:
ORTHOVITA, INC.
Inventors:
Antony Koblish, Erik M. Erbe, Theodore D. Clineff, Gina M. Nagvajara, Charanpreet S. Bagga
Abstract: Novel kits are provided for the delivery of restorative or injectable compositions into an intraosseous space or surgical defect comprising cannulae for accessing an intraosseous space, mandarins insertable into the cannulae and movable therein, one or more catheters and a system for the delivery of aliquots of restorative compositions into the space via the catheters.
Type:
Grant
Filed:
September 2, 2003
Date of Patent:
June 9, 2009
Assignee:
Orthovita, Inc.
Inventors:
Charanpreet S. Bagga, Stephen G Gilbert, Antony Koblish, Maarten Persenaire, Erik M. Erbe
Abstract: Biocompatible bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.
Type:
Grant
Filed:
October 26, 2004
Date of Patent:
May 19, 2009
Assignee:
Orthovita, Inc.
Inventors:
Erik M. Erbe, Theodore D. Clineff, Charanpreet S. Bagga, Gina M. Nagvajara, Antony Koblish
Abstract: A pliable bone restorative having an osteoconductive foam that at least partially surrounds a biocompatible mesh and the foam comprises a biocompatible, resorbable polymer and calcium phosphate.
Type:
Grant
Filed:
October 26, 2004
Date of Patent:
May 12, 2009
Assignee:
Orthovita, Inc.
Inventors:
Charanpreet S. Bagga, Antony Koblish, Erik M. Erbe, Theodore D. Clineff, Steven B. Brown, Gina M. Nagvajara
Abstract: Uniformly sized and shaped particles of metal salts are provided comprised of one or more metal cations in combination with one or more simple oxoacid anions and a general method for the controlled precipitation of said metal salts from aqueous solutions. The methods proceed via the in situ homogeneous production of simple or complex oxoacid anions in which one or more of the nonmetallic elements e.g. Group 5B and 6B (chalcogenides), and 7B (halides) comprising the first oxoacid anion undergo oxidation to generate the precipitant anionic species along with concurrent reduction of the nonmetallic element of a second, dissimilar oxoacid anion. The oxoacid anions are initially present in solution with one or more metal cations known to form insoluble salts with the precipitant anion.
Abstract: Novel fillers comprising combeite glass-ceramic are provided, along with filled polymerizable resin composites. Further provided are methods for making the combeite crystallite-containing novel fillers for use in hardenable, biocompatible bone restorations. Hard, shaped bodies or orthopaedic, dental and other uses are also provided.
Abstract: Novel fillers comprising combeite glass-ceramic are provided. hardenable restorative compositions comprising particulate combeite glass-ceramic provide improved biocompatibility in bone restorations. Hard, shaped bodies for orthopaedic, dental and other uses are also provided.
Abstract: Methods for forming osseous tissue in defects in sites in the appendicular skeleton or sites exhibiting reduced metabolic state using bioactive glass granules containing 40 to 58% SiO.sub.2, 10 to 30% NaO, 10 to 30% CaO, and 0 to 10% P.sub.2 O.sub.5, and in the size range of from 200 to 300 micrometers, are described.
Type:
Grant
Filed:
June 30, 1994
Date of Patent:
August 19, 1997
Assignee:
Orthovita, Inc.
Inventors:
Paul Ducheyne, D. Scott Metsger, Evert Schepers