Abstract: In a non-contact pressure measurement system of a balloon catheter and a non-contact pressure measurement method of the balloon catheter using the same, the system includes a chamber part, a balloon, a tube part, a pump part and a displacement sensor. The chamber part stores a saline solution. The balloon is disposed inside of a body and is configured to be expanded with supply of the saline solution. The tube part is configured to connect the chamber part with the balloon. The pump part is configured to control the supply of the saline solution via the tube part. The displacement sensor is configured to measure an amount of the expansion of the tube part expanded with the supply of the saline solution, in a predetermined section of the tube part.

Abstract: In a focus variable liquid lens and a method of manufacturing the focus variable liquid lens includes a base substrate, an electrode par and a lens unit. The electrode part is formed on the base substrate, having a central electrode and a plurality of electrodes. A printed circuit board is mounted to be electrically connected to the metal layer exposed to outside through the insulating layer. The lens unit has a liquid lens formed at the central electrode, and a light passes through the liquid lens. The liquid lens is located at a center of the central electrode and a focus of the light is located at an optical axis, when a voltage having the same magnitude is applied to the plurality of the electrodes. The liquid lens moves laterally from the central electrode and the focus of the light moves laterally from the center of the central electrode.

Abstract: In a temperature sensor, a wearable device comprising the temperature sensor, and a core temperature measurement method using the temperature sensor, the temperature sensor includes a sensing unit and a substrate. The sensing unit includes a base part, a measuring part mounted on the base part and configured to measure a temperature of a subject body by making contact with the subject body, and a cover part configured to cover the measuring part. The sensing unit is mounted on the substrate. A plurality of slits is formed around a first area of the substrate, and the sensing unit is mounted at the first area of the substrate.

Abstract: In an image processing-based system for measuring moisture and light transmittance and a method for measuring moisture and light transmittance using the same, the image processing-based system includes a coating paper, a photographing box, a microscope and an RGB decision program. The coating paper is coated with coating conditions substantially same as the coating conditions for a metal material. The photographing box is configured to photograph the coating paper, to obtain a first image. The microscope is configured to photograph the coating paper, to obtain a second image. The RGB decision program is configured to obtaining an RGB value of each of the first and second images. Moisture transmittance is evaluated using the RGB value of the first image, and light transmittance is evaluated using the RGB value of the second image.

Abstract: In a method for coating on a surface of a medical PEEK material with titanium to have a microporous structure, titanium is coated on a surface of polyether ether ketone (PEEK) via magnetron sputtering. The surface of the titanium coated on the surface of PEEK is polished via an electromagnetic polishing apparatus. A thin-film with titanium dioxide (TiO2) having a microporous structure is formed on the polished surface of the titanium via an anodic oxidation treatment.

Abstract: A thermally stable polypeptide having FGF7 activity is provided. The polypeptide is a thermally stable polypeptide having FGF7 activity, wherein, in SEQ ID NO: 1, a 120th alanine (A) is substituted with cysteine (C), one including at least one substitution selected from substitution of a 126th lysine (K) with aspartic acid (D) and a 178th lysine (K) with glutamic acid (E) or aspartic acid (D) forms a salt bridge with a 175th arginine (R), and a 133rd cysteine (C) and a 137th cysteine (C) are disulfide bonded.

Abstract: The present invention relates to a polypeptide including an Fc variant produced by substituting a portion of the amino acid sequence of the Fc domain of a human antibody with a different amino acid sequence. The present invention also relates to an antibody including the polypeptide. The Fc variant can find application in a wide range of antibodies and Fc-fusion constructs. In one aspect, the antibody or Fc fusion construct of the present invention is a therapeutic, diagnostic or laboratory reagent, preferably a therapeutic reagent. The Fc variant is suitable for use in the treatment of cancer because its in vivo half-life can be maximized by optimization of the portion of the amino acid sequence. The antibody or Fc fusion construct of the present invention is used to kill target cells that bear a target antigen, for example cancer cells. Alternatively, the antibody or Fc fusion construct of the present invention is used to block, antagonize or agonize a target antigen.

Abstract: In a floating gate semiconductor nanostructure biosensor and a method for manufacturing the biosensor, the nanostructure biosensor includes a substrate, an insulating layer, a nanostructure, a source electrode and a drain electrode, a floating gate and a biological sensing material. The insulating layer is formed on the substrate. The nanostructure is protruded from the insulating layer. The source electrode and the drain electrode are formed on the insulating layer and dispose the nanostructure therebetween. The floating gate has a metal pattern or a polysilicon pattern, and extends with contacting the nanostructure. The biological sensing material has a first end combined with an immobile molecule on the floating gate, and a second end combined with a bio molecule.

Abstract: The present invention relates to a polypeptide including an Fc variant produced by substituting a portion of the amino acid sequence of the Fc domain of a human antibody with a different amino acid sequence. The present invention also relates to an antibody including the polypeptide. The Fc variant can find application in a wide range of antibodies and Fc-fusion constructs. In one aspect, the antibody or Fc fusion construct of the present invention is a therapeutic, diagnostic or laboratory reagent, preferably a therapeutic reagent. The Fc variant is suitable for use in the treatment of cancer because its in vivo half-life can be maximized by optimization of the portion of the amino acid sequence. The antibody or Fc fusion construct of the present invention is used to kill target cells that bear a target antigen, for example cancer cells. Alternatively, the antibody or Fc fusion construct of the present invention is used to block, antagonize or agonize a target antigen.

Abstract: The present invention relates to a composition for screening various signal peptides to select specific ones that allow efficient secretion of a target protein to out of host cells. The present invention also relates to a method for selecting specific signal peptides that express a target protein in host cells and efficiently secrete the target protein to out of the host cells. The use of the composition and/or method according to the present invention enables ultrafast selection of optimal signal peptides for a target protein through barcoding sequences corresponding to the signal peptides, leading to the maximization of the production yield of the recombinant protein.

Abstract: In a floating gate semiconductor nanostructure biosensor and a method for manufacturing the biosensor, the nanostructure biosensor includes a substrate, an insulating layer, a nanostructure, a source electrode and a drain electrode, a floating gate and a biological sensing material. The insulating layer is formed on the substrate. The nanostructure is protruded from the insulating layer. The source electrode and the drain electrode are formed on the insulating layer and dispose the nanostructure therebetween. The floating gate has a metal pattern or a polysilicon pattern, and extends with contacting the nanostructure. The biological sensing material has a first end combined with an immobile molecule on the floating gate, and a second end combined with a bio molecule.

Abstract: In a method for manufacturing conductive polymer electrode by using drop casting, a conductive material is dispersed in a solution, to form a first mixing solution. A first polymer is added and dispersed to the first mixing solution, to form a second mixing solution. A second polymer solution is added and dispersed to the second mixing solution, to form a third mixing solution. The third mixing solution is dropped on a hot plate using a pipette and a solution of the third mixing solution is evaporated, to form a conductive polymer. The adhesive patch is formed. The adhesive patch is attached to the conductive polymer.

Abstract: A fluorescence endoscopic method for visualization of colorectal tissue using a fluoroquinolone antibiotic and a method for diagnosis of lesions of colorectal tissue using the same. The fluorescence endoscopic method for visualization of colorectal tissue includes staining goblet cells of the colorectal tissue with moxifloxacin, which is a fluoroquinolone antibiotic, and exciting the stained goblet cells with single photons in the near UV region or in the visible region, followed by fluorescence endoscopic photographing of the goblet cells, thereby enabling acquisition of morphological information on living tissue without damage to or destruction of the colorectal tissue, while allowing diagnosis of lesions of the colon based on the morphological information on living tissue such as information on the distribution of the goblet cells.

Abstract: A core body temperature measurement device includes a body and an operation unit. The body is fixed to an ear canal of user. The operation unit is combined with a front side of the body, and is configured to be exposed to the ear canal or to be concealed inside, and has a sensor part. the sensor part measures a core body temperature of user when the operation unit is exposed to the ear canal.

Abstract: A core body temperature measurement device includes a fixing frame and a measurement unit. The fixing frame is fixed to an earflap of user. The measurement unit is detachably inserted into the fixing frame and includes an extending part and a temperature sensor. The extending part is bent according to a structure of an ear canal of user and is inserted into the ear canal. The temperature sensor is disposed at an end of the extending part to measure a core body temperature of user.

Abstract: In an image processing-based system for measuring moisture and light transmittance and a method for measuring moisture and light transmittance using the same, the image processing-based system includes a coating paper, a photographing box, a microscope and an RGB decision program. The coating paper is coated with coating conditions substantially same as the coating conditions for a metal material. The photographing box is configured to photograph the coating paper, to obtain a first image. The microscope is configured to photograph the coating paper, to obtain a second image. The RGB decision program is configured to obtaining an RGB value of each of the first and second images. Moisture transmittance is evaluated using the RGB value of the first image, and light transmittance is evaluated using the RGB value of the second image.

Abstract: In a thin film electrode separation method using thermal expansion coefficient, a first solution is coated on a substrate. The first solution coated on the substrate is hardened. The substrate is left in a predetermined time, to form a first thin film having a first thermal expansion coefficient on the substrate. A photoresist is coated on the substrate having the thin film formed thereon. The photoresist coated on the substrate is hardened, to form a photoresist film having a second thermal expansion coefficient. A metal and a passivation layer are formed on the photoresist film. The photoresist film is detached from the first thin film, using difference of a thermal expansion coefficient between the photoresist film and the first thin film.

Abstract: In a method for coating on a surface of a medical PEEK material with titanium to have a microporous structure, titanium is coated on a surface of polyether ether ketone (PEEK) via magnetron sputtering. The surface of the titanium coated on the surface of PEEK is polished via an electromagnetic polishing apparatus. A thin-film with titanium dioxide (TiO2) having a microporous structure is formed on the polished surface of the titanium via an anodic oxidation treatment.

Abstract: A fluorescence lifetime measurement apparatus according to an embodiment of the present invention includes an illumination light generation unit that generates illumination light, a fluorescence photon detection unit that collects fluorescence photons generated by illuminating a sample including fluorescent molecules with the illumination light, a conversion unit that converts the collected fluorescence photons into a first clock signal and converts illumination light that does not pass through the sample into a second clock signal, a first module that analyzes a fluorescence lifetime of the collected fluorescence photons from the conversion unit, a control unit that designates a range of interest (ROI) of the sample from the first module, and a second module that analyzes a fluorescence lifetime of fluorescence photons corresponding to the ROI.

Abstract: The present invention relates to a polypeptide including an Fc variant produced by substituting a portion of the amino acid sequence of the Fc domain of a human antibody with a different amino acid sequence. The present invention also relates to an antibody including the polypeptide. The Fc variant can find application in a wide range of antibodies and Fc-fusion constructs. In one aspect, the antibody or Fc fusion construct of the present invention is a therapeutic, diagnostic or laboratory reagent, preferably a therapeutic reagent. The Fc variant is suitable for use in the treatment of cancer because its in vivo half-life can be maximized by optimization of the portion of the amino acid sequence. The antibody or Fc fusion construct of the present invention is used to kill target cells that bear a target antigen, for example cancer cells. Alternatively, the antibody or Fc fusion construct of the present invention is used to block, antagonize or agonize a target antigen.