Patents Assigned to PGI Drug Discovery LLC.
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Patent number: 11958862Abstract: Disclosed are compounds of formula (I): and pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disease and disorders in a subject in need are also disclosed.Type: GrantFiled: January 11, 2021Date of Patent: April 16, 2024Assignees: Sumitomo Pharma America, Inc., PGI Drug Discovery LLCInventors: Linghong Xie, Michele L. R. Heffernan, Philip Glyn Jones, Taleen G. Hanania
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Publication number: 20220387382Abstract: Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.Type: ApplicationFiled: January 13, 2022Publication date: December 8, 2022Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Liming SHAO, John Emmerson CAMPBELL, Michael Charles HEWITT, Una CAMPBELL, Taleen G. HANANIA
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Patent number: 11491133Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.Type: GrantFiled: August 12, 2020Date of Patent: November 8, 2022Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Carrie A. Bowen, Douglas F. Burdi, Michele L. R. Heffernan, Lee W. Herman, Linghong Xie
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Publication number: 20220340588Abstract: Disclosed are compounds of formula (I): and pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disease and disorders in a subject in need are also disclosed.Type: ApplicationFiled: January 11, 2021Publication date: October 27, 2022Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Linghong XIE, Michele L.R. HEFFERNAN, Philip Glyn JONES, Taleen G. HANANIA
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Publication number: 20220185799Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.Type: ApplicationFiled: October 29, 2021Publication date: June 16, 2022Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Linghong XIE, Philip Glyn JONES, Kerry L. SPEAR, Noel Aaron POWELL, Taleen G. HANANIA, Vadim ALEXANDROV
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Patent number: 11332462Abstract: Provided herein are thiophene compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.Type: GrantFiled: December 20, 2019Date of Patent: May 17, 2022Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: John Emmerson Campbell, Una Campbell, Taleen G. Hanania, Liming Shao
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Patent number: 11192885Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.Type: GrantFiled: May 6, 2019Date of Patent: December 7, 2021Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Linghong Xie, Philip Glyn Jones, Kerry L. Spear, Noel Aaron Powell, Taleen G. Hanania, Vadim Alexandrov
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Publication number: 20210300942Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein Ring B, A1, A2, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.Type: ApplicationFiled: February 19, 2021Publication date: September 30, 2021Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Milan CHYTIL, Sharon ENGEL, Taleen G. HANANIA, Vadim ALEXANDROV, Emer LEAHY
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Publication number: 20210267938Abstract: Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.Type: ApplicationFiled: November 19, 2020Publication date: September 2, 2021Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Liming SHAO, John Emmerson CAMPBELL, Michael Charles HEWITT, Una CAMPBELL, Taleen G. HANANIA
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Patent number: 11077090Abstract: Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need thereof are also disclosed.Type: GrantFiled: July 28, 2017Date of Patent: August 3, 2021Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Vadim Alexandrov, Carrie A. Bowen, Taleen G. Hanania, Noel Aaron Powell
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Publication number: 20210093606Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.Type: ApplicationFiled: August 12, 2020Publication date: April 1, 2021Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Carrie A. Bowen, Douglas F. Burdi, Michele L. R. Heffernan, Lee W. Herman, Linghong Xie
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Patent number: 10927124Abstract: Disclosed are compounds of formula (I): and pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disease and disorders in a subject in need are also disclosed.Type: GrantFiled: December 10, 2018Date of Patent: February 23, 2021Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Linghong Xie, Michele L. R. Heffernan, Philip Glyn Jones, Taleen G. Hanania
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Patent number: 10894033Abstract: Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.Type: GrantFiled: February 14, 2020Date of Patent: January 19, 2021Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Liming Shao, John Emmerson Campbell, Michael Charles Hewitt, Una Campbell, Taleen G. Hanania
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Publication number: 20200323819Abstract: Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.Type: ApplicationFiled: February 14, 2020Publication date: October 15, 2020Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Liming SHAO, John Emmerson CAMPBELL, Michael Charles HEWITT, Una CAMPBELL, Taleen G. HANANIA
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Patent number: 10780074Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.Type: GrantFiled: August 1, 2018Date of Patent: September 22, 2020Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Carrie A. Bowen, Douglas F. Burdi, Michele L. R. Heffernan, Lee W. Herman, Linghong Xie
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Publication number: 20200277286Abstract: Provided herein are thiophene compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.Type: ApplicationFiled: December 20, 2019Publication date: September 3, 2020Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: John Emmerson CAMPBELL, Una CAMPBELL, Taleen G. HANANIA, Liming SHAO
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Patent number: 10556890Abstract: Provided herein are thiophene compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.Type: GrantFiled: December 22, 2017Date of Patent: February 11, 2020Assignees: Sunovion Pharmaceuticals Inc., PGI DRUG DISCOVERY LLCInventors: John Emmerson Campbell, Una Campbell, Taleen G. Hanania, Liming Shao
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Publication number: 20200024286Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein Ring B, A1, A2, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.Type: ApplicationFiled: May 6, 2019Publication date: January 23, 2020Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Milan CHYTIL, Sharon ENGEL, Taleen G. HANANIA, Vadim ALEXANDROV, Emer LEAHY
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Publication number: 20190389845Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.Type: ApplicationFiled: May 6, 2019Publication date: December 26, 2019Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLCInventors: Linghong Xie, Philip Glyn JONES, Kerry L. SPEAR, Noel Aaron POWELL, Taleen G. HANANIA, Vadim ALEXANDROV
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Publication number: 20190308990Abstract: Disclosed are compounds of formula (I): and pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disease and disorders in a subject in need are also disclosed.Type: ApplicationFiled: December 10, 2018Publication date: October 10, 2019Applicants: PGI Drug Discovery LLCInventors: Linghong Xie, Michele L.R. Heffernan, Philip Glyn Jones, Taleen G. Hanania
