Patents Assigned to Pirbright Institute
  • FOOT AND MOUTH DISEASE VIRUS WITH INCREASED STABILITY AND ITS USE AS VACCINE
    Publication number: 20130230549
    Abstract: The present invention provides a foot and mouth disease (FMD) virus having improved stability compared to the field isolate of the same subtype, wherein the virus comprises one or more amino acid mutations along a line of symmetry of the capsid structure. The present invention also relates to a vaccine comprising such an FMD virus and its use to prevent foot and mouth disease.
    Type: Application
    Filed: September 8, 2011
    Publication date: September 5, 2013
    Applicant: THE PIRBRIGHT INSTITUTE
    Inventors: Veronica Fowler, Nick Knowles, Paul Barnett
  • VACCINE
    Publication number: 20130216569
    Abstract: The present invention provides a polypeptide comprising the amino acid sequence as shown as SEQ ID No. 1 or a homologue or fragment thereof, a nucleic acid capable of encoding such a polypeptide and a vaccine comprising such a polypeptide/nucleic acid. The vaccine may be used for the treatment and/or prevention of a disease associated with an apicomplexan parasite.
    Type: Application
    Filed: August 2, 2011
    Publication date: August 22, 2013
    Applicant: THE PIRBRIGHT INSTITUTE
    Inventors: Damer Blake, Adrian Smith, Martin Shirley
  • Vector
    Patent number: 8501466
    Abstract: The present invention relates to a herpes virus vector which comprises a modified genomic sequence encoding a microRNA (miRNA) against a target sequence. The herpes virus vector may be used as or in a vaccine to prevent and/or treat a disease.
    Type: Grant
    Filed: June 11, 2009
    Date of Patent: August 6, 2013
    Assignee: The Pirbright Institute
    Inventors: Venugopal Nair, Luke Lambeth
  • Diagnose of mycobacterial infections by determination of IFN-gamma
    Patent number: 8455201
    Abstract: The present invention provides a method for diagnosing a mycobacterial infection in a subject, involving the following steps: (i) collection of a sample from the subject; (ii) incubation of the sample from (i) with an antigen preparation for 12 hours or less; and (iii) analysis of ?-IFN in the sample from (ii). The invention also provides a diagnostic kit for use in such a method.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: June 4, 2013
    Assignee: The Pirbright Institute
    Inventors: Jayne Hope, Paul Sopp, Chris Howard