Abstract: According to various embodiments, a method for reducing heading error in a magnetometer that uses Rb-87 atoms is disclosed. The method includes varying a direction and magnitude of a magnetic field at different spin polarization regimes. According to various embodiments, a magnetometer adapted for reduced heading error is disclosed. The magnetometer includes a multipass cell containing Rb-87 vapor, a pump laser operated in a pulse mode that is synchronous with a Larmor frequency, and two orthogonal probe lasers configured to rotate to vary a direction and magnitude of a magnetic field at different spin polarization regimes.

Abstract: Disclosed is a process to make nanoparticles highly loaded with water soluble actives, including biologics such as proteins and peptides, which are stabilized by random copolymers. The random copolymers used have all been approved by the FDA for oral formulations. The nanoparticles have a hydrophilic core and a hydrophobic corona and can be further processed through a number of different routes. The process to make these particles is highly scalable and could be used industrially.

Abstract: The invention described herein relates to sterically stabilized colloidal constructs comprising preformed colloidal particles encapsulated within a polymeric shell. The constructs, which are controllably sized, are nanoparticles comprising hydrophobic elements, electrostatically charged particles with hydrophobic surfaces, hydrophobic inorganic nanostructures, and amphiphilic copolymers with hydrophobic domains and hydrophilic domains. The constructs are made by a process that allows for the simultaneous encapsulation of a preformed colloidal agent as well as a dissolved hydrophobic active within the core of the polymeric nanoparticle. Among the actives incorporated in various embodiments are organic fluorescent dyes, metal nanostructures and superparamagnetic materials for use in combined fluorescence, optical and magnetic resonance imaging applications, and hydrophobic drugs for therapeutic applications.

Abstract: The present invention relates to compositions comprising isolated, single stranded RNA molecules and pharmaceutically acceptable carriers suitable for injection. The present invention relates to methods for stimulating an immune response and treating tumors. The present invention further relates to kits comprising a cancer vaccine and compositions of the present invention for use as an adjuvant to cancer vaccines.

Abstract: Nanoemulsion compositions, processes, and methods that include dihydromyricetin (DHM).

Abstract: Methods and systems for organic vapor jet deposition are provided, where an exhaust is disposed between adjacent nozzles. The exhaust may reduce pressure buildup in the nozzles and between the nozzles and the substrate, leading to improved deposition profiles, resolution, and improved nozzle-to-nozzle uniformity. The exhaust may be in fluid communication with an ambient vacuum, or may be directly connected to a vacuum source.

Abstract: A 10-formyl-THF pathway for producing NADPH is useful in the diagnosis and treatment of cancer and metabolic disease, in the development of new antineoplastic agents and/or regimens, in the development of new methods for measuring metabolic pathway activity, and in the development of new therapeutics for treating metabolic disease.

Abstract: According to various embodiments, a method for detecting security vulnerabilities in at least one of cyber-physical systems (CPSs) and Internet of Things (IoT) devices is disclosed. The method includes constructing an attack directed acyclic graph (DAG) from a plurality of regular expressions, where each regular expression corresponds to control-data flow for a known CPS/IoT attack. The method further includes performing a linear search on the attack DAG to determine unexploited CPS/IoT attack vectors, where a path in the attack DAG that does not represent a known CPS/IoT attack vector represents an unexploited CPS/IoT attack vector. The method also includes applying a trained machine learning module to the attack DAG to predict new CPS/IoT vulnerability exploits. The method further includes constructing a defense DAG configured to protect against the known CPS/IoT attacks, the unexploited CPS/IoT attacks, and the new CPS/IoT vulnerability exploits.

Abstract: Disclosed is a spectroscopic device, system, and method for measuring the concentration of one or more molecular species of interest in a gas, liquid or solid sample, where the device may be portable, may be commercially manufactured, and/or may be adapted to existing systems and/or integrated with new systems to provide optical gas sensing for such systems. The disclosed devices, systems, and methods can be particularly useful in monitoring the purity of, e.g., a certain gas species, including determining whether a gas mixture contains certain gas species above a set concentration limit.

Abstract: This disclosure generally relates to character animation. More specifically, this disclosure relates to pose selection using data analytics techniques applied to training data, and generating 2D animations of illustrated characters using performance data and the selected poses. An example process or system includes extracting sets of joint positions from a training video including the subject, grouping the plurality of frames into frame groups using the sets of joint positions for each frame, identifying a representative frame for each frame group using the frame groups, clustering the frame groups into clusters using the representative frames, outputting a visualization of the clusters at a user interface, and receiving a selection of a cluster for animation of the subject.

Abstract: According to various embodiments, a power converter circuit is disclosed. The power converter circuit includes a plurality of voltage splitting units (VSUs) coupled to a plurality of current splitting units (CSUs). The VSUs are connected to each other in series and the CSUs are connected to each other in parallel. The VSUs each have a fixed voltage conversion ratio and are operated at a lower frequency than the CSUs. The CSUs each have an adjustable voltage conversion ratio and are operated at a higher frequency than the VSUs.

Abstract: Disclosed is a method and system for the phase separation of folded domains, and more particularly, to inducing clusters of folded domains as part of a drug-based screening application. The system and method utilize one or more first fusion proteins (100, 101), each first fusion protein comprising a first region (110) fused to a second region (120), the first region (110) comprising at least one light sensitive protein (115) or cognate partner of a light sensitive protein (116), and the second region (120) comprising one or more folded RNA binding domains (RBDs), disordered RBDs, folded non-RBD domains, or combination thereof (125).

Abstract: According to various embodiments, a direct magnetic gradiometer having intrinsic subtraction of rotation signals from two oppositely polarized atomic ensembles within a single multi-pass cell is disclosed. The gradiometer includes three convex spherical mirrors aligned in a V-shape geometry. The three convex spherical mirrors include a front mirror and two back mirrors. The gradiometer further includes a probe laser beam. The laser beam is configured to be initially focused at a near-zero angle into a hole at a center of the front mirror such that the laser beam expands at the back mirrors and nearly overlaps with itself while undergoing multiple reflections between the front and back mirrors. The laser beam is further configured to be refocused to the front mirror at different spots in a number equal to half of total beam passes before exiting.

Abstract: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.

Abstract: Methods described herein, in some embodiments, permit extraction of particle structural and/or surface charge data from gradient induced particle motion in channels. In one aspect, a method of manipulating particle motion comprises introducing a fluid into a channel, the fluid comprising particles, and driving particle accumulation to a preselected location in the channel by setting advective velocity of the fluid to offset diffusiophoretic mobility of the particles at the preselected location.

Abstract: Various embodiments are directed to Reed-Muller decoding systems and methods based on recursive projections and aggregations of cosets decoding, exploiting the self-similarity of RM codes, and extended with list-decoding procedures and with outer-code concatenations

Abstract: According to various embodiments, a system for using magnetic reconnection to accelerate plasma is disclosed. The system includes a pair of electrodes including two concentric rings separated by an electrode gap and held at different electrostatic potential by applying a voltage to generate an inter-electrode electric field. The system further includes a plurality of magnetic coils configured to produce magnetic field lines that connect the pair of electrodes. The system additionally includes a gas injector configured to inject gas into the electrode gap, the injected gas being partially ionized by the inter-electrode electric field to generate a poloidal current that flows along open magnetic field lines across the electrode gap.

Abstract: This disclosure generally relates to character animation. More specifically, but not by way of limitation, this disclosure relates to pose selection using data analytics techniques applied to training data, and generating 2D animations of illustrated characters using performance data and the selected poses. An example process or system includes obtaining a selection of training poses of the subject and a set of character poses, obtaining a performance video of the subject, wherein the performance video includes a plurality of performance frames that include poses performed by the subject, grouping the plurality of performance frames into groups of performance frames, assigning a selected training pose from the selection of training poses to each group of performance frames using the clusters of training frames, generating a sequence of character poses based on the groups of performance frames and their assigned training poses, outputting the sequence of character poses.

Abstract: A system for photonic computing, preferably including: an input module, computation module, and/or control module, wherein the computation module preferably includes one or more filter banks and/or detectors. A photonic filter bank system, preferably including two waveguides and a plurality of optical filters arranged between the waveguides. A method for photonic computing, preferably including: controlling a computation module; controlling an input module; and/or receiving outputs from the computation module.

Abstract: Compositions including dihydromyricetin (DHM) and methods for forming them through spray drying.