Abstract: The disclosure relates generally to a cell culture apparatus and a cell culture method. One aspect of the disclosure provides a perfusion cell culture bag comprising one or more polymer films, having edges bonded together to form edges around an undivided interior compartment of the bag; first and second ports each formed in an exterior surface of the bag; first and second liquid-permeable tubes each extending into and in fluid communication with the interior compartment of the bag and operatively coupled to a respective port; and a third port formed in an exterior surface of the bag, the third port being in fluid communication with the interior compartment of the bag; wherein the first tube comprises a first inner support structure defining a central lumen of the tube and a first outer filter layer surrounding the first inner support structure.

Abstract: The present disclosure relates to methods for preparing a hydrophilic composition including intimately mixing a silicone component including at least one polysiloxane and a polymer component, and to hydrophobic polymer compositions prepared thereby. One aspect of the disclosure provides an article having a major exterior surface, the article comprising an intimate mixture of a silicone component including at least one polysiloxane; and a polymer component including at least one hydrophilic polymer having a water-absorption capacity of at least 50 wt. %; wherein the silicone component and the polymer component are present in the mixture in a dry weight ratio within the range of 99.9:0.1 to 30:70. In certain desirable embodiments as otherwise described herein, the intimate mixture is disposed at an exterior surface of the article, e.g., at the major exterior surface of the article.

Abstract: The present disclosure relates to improved magnetic mixing assemblies and mixing system. The magnetic mixing assemblies can provide improved mixing action, ease of use, and low friction. The mixing assemblies can be adapted for use with a wide variety of containers including narrower neck containers and flexible containers.

Abstract: A composite tube includes a first layer including a cross-linked polyolefin elastomer, wherein the first layer is configured for fluid contact; and a second layer adjacent to the first layer, the second layer including an elastomer.

Abstract: Systems and methods are disclosed that include an additive manufacturing assembly having a printing area, a first nozzle comprising a first nozzle having a first aperture diameter and configured to dispense a first material in the printing area, and a second nozzle comprising a second nozzle having a second aperture diameter that is larger than the first aperture diameter and configured to dispense a second material in the printing area.

Abstract: Embodiments described herein are generally directed to an annular seal including: an annular body defining a cross-section down a central axis, the annular body including: a first linear section oriented down a first plane; a first portion contiguous with the first end of the first linear section, the first portion being curved with respect to the first linear section and in accordance with a first predetermined radius, the first portion extending to a first distal end; a second portion contiguous with the second end of the first linear section, the second portion including: a second linear section oriented down a second plane non-parallel to the first plane; and at least one discrete, radially-oriented tab contiguous with the second linear section and oriented along a circumference of the annular body.

Abstract: An article includes a layer including a melt processable fluoropolymer, wherein the fluoropolymer includes a copolymer of a tetrafluoroethylene and a perfluoroether, wherein the article has an ultraviolet transmittance of at least about 50% at a thickness of about 0.040 inches to about 0.062 inches when exposed to ultraviolet radiation of about 200 nm to about 280 nm. Further provided is a method of making the article and an apparatus for purifying water including an article, such as a flexible tube.

Abstract: A connection including a first profile having a first end and a first lumen, the first profile including a first polymeric material and a second profile having a second end and a second lumen, the second profile including a second polymeric material, a metal, or combination thereof, wherein the first end and the second end are coincidently welded via an ionized gas treatment.

Abstract: A liquid recovery filter assembly for recovering filtered liquid trapped within a core or downstream side of a filter element. Multiple embodiments each include a recovery port and a recovery filter in fluid communication with the core or downstream side of the filter element. The recovery port is opened following filtration operations to permit and to facilitate filtered liquid to flow from a downstream or outlet port, thus allowing recovery of liquid remaining in the filter core or downstream side following filtering operations. The recovery filter permits the introduction of pressurized gas to force the filtered liquids from the filter assembly without compromising the sterility and/or non-contaminant condition of the liquid.

Abstract: The present application is directed to a packaging container including a body including; a first portion including a coupling feature; a second portion including a coupling feature and complementary to the first portion; and a hinge portion coupling the first portion to the second portion adapted to move the packaging container from an open position to a closed position around a product, where the first portion and the second portion combine to form a void port in the closed position.

Abstract: The present disclosure relates to a composite article that may include a plastic component, and a silicone component bonded the plastic component. The plastic component and the silicone component may be bonded at an intersecting region between a first surface of the plastic component and a first surface of the silicone component. The intersecting region may include at least one of an acetone content of not greater than about 0.2 ppm, an MEK content of not greater than about 0.2 ppm, or a trimethylsilanol content of not greater than about 0.2 ppm.

Abstract: Systems and methods include providing an annular seal for an assembly. The seal includes a metallic annular body comprising an inner sealing leg having a first sealing lip, a second sealing lip, and a valley disposed between the first sealing lip and the second sealing lip. The valley contains a plating reserve, such that the plating thickness in the valley is greater than the plating thickness on the first sealing lip and the second sealing lip.

Abstract: A bearing including a sidewall including an open metal substrate at least partially embedded in a low friction material, the sidewall further including a generally cylindrical body; and a flange contiguous with and extending from an axial end of the generally cylindrical body, where at least one of 1) the flange includes a multiple wall construction including a plurality of flange sidewalls in contact with each other along at least 25% of a radial length of the flange, or 2) the sidewall or the flange comprises an outward conductive region and an inward conductive region.

Abstract: A system for storing pharmaceuticals or biological media comprising a bag including a flexible sidewall defining an opening; and a vent coupled with the flexible sidewall at the opening and defining a vent passageway between an internal volume of the bag and an external environment, wherein the vent is coupled with the bag at a location spaced apart from and above the opening.

Abstract: A polyurethane foam may include a base polyol component, a phosphorous polyol component, an expandable graphite, and melamine. The polyurethane foam may have a VO rating based on a UL94 flame retardancy test performed at a polyurethane foam thickness of 3.5 mm and a polyurethane foam density of 380 kg/m3.

Abstract: The present disclosure relates to a low friction bearing liner for a solenoid may include a low friction layer. The low friction layer may include a first fluoropolymer matrix component and a first thermoplastic filler component distributed throughout the first fluoropolymer matrix component. The content of the first fluoropolymer matrix component may be at least about 1 wt. % and not greater than about 99 wt. % for a total weight of the first low friction layer. The content of the first thermoplastic filler component may be at least about 1 wt. % and not greater than about 99 wt. % for a total weight of the first low friction layer.

Abstract: A connection includes: a first profile having a first end, the first profile including a first polymeric material comprising a thermoset material; and a second profile having a second end, the second profile including a second polymeric material, a metal, or combination thereof, wherein the first end and the second end are coincidently bonded without a bonding material at an interface of the first end and the second end.

Abstract: A composite film may include a first transparent substrate and a first anti-reflective coating overlying a first surface of the first transparent substrate. The first anti-reflective coating may include a first UV curable acrylate binder, a photo initiator component, and silica nanoparticles dispersed within the first anti-reflective coating. The first anti-reflective coating may further include a ratio AC1SiO2/AC1B of at least about 0.01 and not greater than about 1.3. The composite film may further have a VLT of at least about 93.0% and a haze value of not greater than about 3%.

Abstract: The present disclosure relates to a multilayer tube that may include an inner layer and an outer layer. The inner layer may include a fluoroether elastomer and the outer layer may include a non-fluoroether based elastomer. The multilayer tube may further include an adhesion force between the inner layer and the outer layer of at least about 1 ppi.

Abstract: The present disclosure relates to a multilayer composite that may include a first porous layer, and a first barrier layer overlying the first porous layer. The first barrier layer may include a polyaramid material, a polyimide material, or any combination thereof. The multilayer composite may have a flame resistance rating of at least about 180° C. and a 50% strain compression rating of not greater than about 600 kPa.