Patents Assigned to Saint Jude Pharmaceuticals, Inc.
  • Patent number: 7635722
    Abstract: An invention relating to therapeutic pharmacological agents and methods to chemically induce intracellular hyperthermia and/or free radicals for the diagnosis and treatment of infections, malignancy and other medical conditions. The invention relates to a process and composition for the diagnosis or killing of cancer cells and inactivation of susceptible bacterial, parasitic, fungal, and viral pathogens by chemically generating heat, and/or free radicals and/or hyperthermia-inducible immunogenic determinants by using mitochondrial uncoupling agents, especially 2,4 dinitrophenol and, their conjugates, either alone or in combination with other drugs, hormones, cytokines and radiation.
    Type: Grant
    Filed: July 27, 1999
    Date of Patent: December 22, 2009
    Assignee: Saint Jude Pharmaceuticals, Inc.
    Inventors: Nicholas Bachynsky, Woodie Roy