Patents Assigned to SHIBUYA CORPORATION
  • Patent number: 10120264
    Abstract: A pumping beam L1 is caused to be incident on an end surface 4A of a nonlinear crystal 4, and a seed beam L2, the diameter of which is increased by a concave lens 6, is collected and adjusted into a collimated beam by a convex lens 7 and caused to be incident on the end surface 4A described above. The pumping beam L1 and the seed beam L2 are caused to be incident on the end surface 4A with the pumping beam L1 and the seed beam L2 superimposed on each other, whereby the nonlinear crystal 4 generates a terahertz wave TH.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: November 6, 2018
    Assignee: SHIBUYA CORPORATION
    Inventors: Toshiaki Naka, Motoi Sasaki, Akito Tsuchiya
  • Patent number: 10106769
    Abstract: An automatic culturing device configured such that, in a work chamber 2a maintained in a sterile state, first and second robots 6 and 7 are arranged so that the movable ranges thereof partially overlap each other, and such that liquid supply means 10 which supplies liquids, containing a culture medium and liquid medicine, to containers held by the robots, and temporary placement sections (handing-over table 42, centrifuge tube holder 43, and heated room 44), each of which hands over the containers between the first and second robots, are provided in the movable ranges of the first and second robots, which ranges overlap each other. The first robot takes out the containers housed in housing means (rotary stocker 8), and the second robot holds and transports the containers handed over from the first robot via the temporary placement section. The cultivating operation can be efficiently performed.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: October 23, 2018
    Assignee: SHIBUYA CORPORATION
    Inventors: Masahiro Sakamoto, Noriaki Nishimura
  • Patent number: 10093892
    Abstract: An isolator system 1 includes: a main isolator 3 in which an aseptic state is maintained and which is for performing an aseptic operation; an incubator 4 in which the aseptic state is maintained and which is connected to the main isolator 3 and is for culturing cells and the like; decontamination means 35 for decontaminating the inside of the main isolator 3; and a decontamination station 9 that decontaminates the inside of the incubator 4. The isolator system 1 further includes a blocking member 30 for sealing a connection port 13 from the outside, the port being provided in the main isolator 3 and being for connection with the incubator 4. When the inside of the main isolator 3 is decontaminated, the connection port 13 is sealed from the outside with the blocking member 30. The isolator system that can efficiently decontaminate the main isolator and the subisolator connected to this main isolator can be provided.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: October 9, 2018
    Assignee: SHIBUYA CORPORATION
    Inventors: Tetsuya Nishimura, Katsuki Hashimoto, Kazuhito Tanimoto
  • Patent number: 10080832
    Abstract: A filter CF1 for filtering dialysis fluid comprises the following: a housing 52 inside of which a filter material 51 is accommodated and which is vertically long; an introduction port 53 that is disposed in the lower part of the housing and that introduces dialysis fluid from an upstream-side flow path 23a; a filtered fluid lead-out port 54 through which filtered dialysis fluid, which has passed through the filter material, is lead out from the upper part of the housing to a downstream-side flow path 23b; and an unfiltered fluid lead-out port 55 through which unfiltered fluid is lead out from the upper part of the housing to a waste fluid flow path 57. When removing the filter from a dialysis fluid circuit 4, fluid is suctioned from the inside of the housing via the upstream-side flow path by using fluid suction means 64A, and a gas is caused to flow into the housing from at least either one of the waste fluid flow path and the downstream-side flow path by using gas inflow means 65.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: September 25, 2018
    Assignee: SHIBUYA CORPORATION
    Inventors: Kosho Matsuzaki, Shingo Saito, Yuki Nakamura
  • Patent number: 10031399
    Abstract: A pumping beam L1 enters from a pumping beam projector 3 into one end surface 2a of a nonlinear crystal 2, the pumping beam L1 and idler wave L2 are generated from another end surface 2b of the nonlinear crystal 2. The pumping beam L1 emitted from the other end surface 2b of the nonlinear crystal 2 is reflected and re-enters as a pumping beam L? into the other end surface 2b and the idler wave L2 generated from the other end surface 2b of the nonlinear crystal is reflected by the reflection optical system 6 and re-enters as a seed beam L2? into the other end surface 2b. The idler wave L2 enters as the seed beam L2? together with the pumping beam L1? into the nonlinear crystal and thus a terahertz wave with a large output and including a plurality of wavelengths can be generated.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: July 24, 2018
    Assignee: SHIBUYA CORPORATION
    Inventors: Toshiaki Naka, Motoi Sasaki, Akito Tsuchiya
  • Publication number: 20180178931
    Abstract: A filling nozzle provided with a filling cylinder, an air-injection cylinder, and an air-supply unit. The filling cylinder is configured such that an auger rotates about the axis thereof to discharge powder through an opening provided at the lower end of the filling cylinder. The air-injection cylinder is fitted to the exterior of the filling cylinder to form an annular space between the filling cylinder and the air-injection cylinder. The air-supply unit supplies air in the annular space. A tip portion of the air-injection cylinder extends downward below the opening and has an air-discharge mouth formed in a tapered shape such that the tip portion has a diameter smaller than that of the opening.
    Type: Application
    Filed: December 21, 2017
    Publication date: June 28, 2018
    Applicant: SHIBUYA CORPORATION
    Inventors: Tetsuya SENO, Masato OHTA
  • Patent number: 9897893
    Abstract: In a terahertz wave generation apparatus including a first non-linear optical crystal 3 on which first laser L1 and second laser L2 from laser generation means 2 are incident to generate terahertz wave TH1, the laser generation means includes a second non-linear optical crystal 7 on which laser having the same wavelength as that of the second laser is incident to generate idler light L1 including a plurality of wavelengths, and makes the idler light L1 generated from the second non-linear optical crystal incident on the first non-linear optical crystal as the first laser L1, to generate terahertz wave including a plurality of wavelengths from the first non-linear optical crystal 3, and wavelength selection means including a transmission section which transmits an idler light having the specific wavelength in the idler light including the plurality of wavelengths can be provided, as needed.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: February 20, 2018
    Assignee: SHIBUYA CORPORATION
    Inventors: Kodo Kawase, Toshiaki Naka, Motoi Sasaki, Akito Tsuchiya
  • Patent number: 9878062
    Abstract: A decontamination operation chamber is partitioned into a first operation chamber and a second operation chamber. A connecting portion that connects the first operation chamber and the second operation chamber can be closed. The pressure of the first operation chamber and the second operation chamber is adjusted by a pressure-adjusting mechanism. When the connecting portion is opened and the first operation chamber and the second operation chamber are connected, an inlet portion for the first operation chamber and an outlet portion for the second operation chamber are closed and air flow is generated from the second operation chamber to the first operation chamber by the pressure-adjusting mechanism. When carrying an object into an aseptic manipulation chamber, the object is housed in the first operation chamber and a first decontamination operation is performed, then the object is transferred to the second operation chamber and a second decontamination operation is performed.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: January 30, 2018
    Assignee: SHIBUYA CORPORATION
    Inventors: Masaharu Shomura, Takuya Funazuka
  • Publication number: 20180001316
    Abstract: An isolator comprises a manipulation chamber isolated from the external atmosphere, a door for opening and closing a portal formed on the manipulation chamber, a linear guide mechanism for guiding a linear motion of a front-side edge of the door along the portal, and a rotation guide mechanism defining a rotation of the door about an axis coinciding with the front-side edge. The door is closed by positioning the front-side edge at the front side of the manipulation chamber, and the door is opened inward into the manipulation chamber by moving the front-side edge toward the back side while rotating the door about the front-side edge.
    Type: Application
    Filed: June 28, 2017
    Publication date: January 4, 2018
    Applicant: SHIBUYA CORPORATION
    Inventor: Kanjun YAMAMOTO
  • Patent number: 9803168
    Abstract: An incubator 1 includes a cultivating chamber 4 for cultivating culture in a plurality of containers 3 and a supply device 5 provided outside the cultivating chamber 4 and supplying steam into the cultivating chamber 4 for humidification. The supply device 5 includes a supply chamber 5A in which a tray 42 for reserving water is accommodated and an ultrasonic atomizing device 43 for atomizing water. The water in the tray 42 is easily made into steam by the ultrasonic atomizing device 43, passes through an HEPA filter 45 provided in an opening portion 5B and is supplied into the circulation passage 37 of the cultivating chamber 4.
    Type: Grant
    Filed: January 25, 2016
    Date of Patent: October 31, 2017
    Assignee: SHIBUYA CORPORATION
    Inventors: Tetsuya Nishimura, Masaomi Shioya, Katsuki Hashimoto
  • Publication number: 20170306285
    Abstract: An operation isolator forms an aseptic space. An incubator is connected to the operation isolator, in which cells are stored and cultured. A storage chamber stores articles used in the operation isolator. In order to carry articles from the outside into the storage chamber, a decontamination pass-box is provided. The storage chamber and the operation isolator are directly or indirectly connected to each other.
    Type: Application
    Filed: September 18, 2015
    Publication date: October 26, 2017
    Applicants: Public University Corporation Yokohama City University, Biomedica Solution Co., Ltd., SHIBUYA CORPORATION
    Inventors: Hideki TANIGUCHI, Takanori TAKEBE, Keisuke SEKINE, Atsushi NAKAO, Takashi HIROMATSU, Hironobu SUNAYAMA, Tetsuya NISHIMURA
  • Patent number: 9789480
    Abstract: An aseptic manipulation system comprises first and second operation chambers, an aseptic manipulation chamber, and a control unit. The control unit controls the ventilation of the first operation chamber for more than a first specified number of times, after an object is introduced into the first operation chamber, and ventilates the second operation chamber for more than a second specified number of times that is greater than the first specified number of times, after the object is transferred into the second operation chamber from the first chamber.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: October 17, 2017
    Assignee: SHIBUYA CORPORATION
    Inventors: Takuya Funazuka, Masaharu Shomura
  • Publication number: 20170281850
    Abstract: A filter CF1 for filtering dialysis fluid comprises the following: a housing 52 inside of which a filter material 51 is accommodated and which is vertically long; an introduction port 53 that is disposed in the lower part of the housing and that introduces dialysis fluid from an upstream-side flow path 23a; a filtered fluid lead-out port 54 through which filtered dialysis fluid, which has passed through the filter material, is lead out from the upper part of the housing to a downstream-side flow path 23b; and an unfiltered fluid lead-out port 55 through which unfiltered fluid is lead out from the upper part of the housing to a waste fluid flow path 57. When removing the filter from a dialysis fluid circuit 4, fluid is suctioned from the inside of the housing via the upstream-side flow path by using fluid suction means 64A, and a gas is caused to flow into the housing from at least either one of the waste fluid flow path and the downstream-side flow path by using gas inflow means 65.
    Type: Application
    Filed: August 19, 2015
    Publication date: October 5, 2017
    Applicant: SHIBUYA CORPORATION
    Inventors: Kosho MATSUZAKI, Shingo SAITO, Yuki NAKAMURA
  • Patent number: 9739658
    Abstract: The present invention relates to a cell peeling recognizing device and a cell peeling recognizing method. When a moving part (robot 6) moves culture vessel 5, imaging device 14 images an interior of culture vessel 5 a plurality of times as the cells move inside the culture vessel due to the moment of inertia, and recognizing part 10a recognizes the peeled state of cells C by comparing various sets of the captured imaging data. The peeled state of cells in the culture vessel can be determined with high precision.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: August 22, 2017
    Assignee: SHIBUYA CORPORATION
    Inventor: Daisuke Watanabe
  • Publication number: 20170130189
    Abstract: An automatic culturing device configured such that, in a work chamber 2a maintained in a sterile state, first and second robots 6 and 7 are arranged so that the movable ranges thereof partially overlap each other, and such that liquid supply means 10 which supplies liquids, containing a culture medium and liquid medicine, to containers held by the robots, and temporary placement sections (handing-over table 42, centrifuge tube holder 43, and heated room 44), each of which hands over the containers between the first and second robots, are provided in the movable ranges of the first and second robots, which ranges overlap each other. The first robot takes out the containers housed in housing means (rotary stocker 8), and the second robot holds and transports the containers handed over from the first robot via the temporary placement section. The cultivating operation can be efficiently performed.
    Type: Application
    Filed: June 12, 2015
    Publication date: May 11, 2017
    Applicant: SHIBUYA CORPORATION
    Inventors: Masahiro SAKAMOTO, Noriaki NISHIMURA
  • Publication number: 20160339130
    Abstract: A decontamination operation chamber is partitioned into a first operation chamber and a second operation chamber. A connecting portion that connects the first operation chamber and the second operation chamber can be closed. The pressure of the first operation chamber and the second operation chamber is adjusted by a pressure-adjusting mechanism. When the connecting portion is opened and the first operation chamber and the second operation chamber are connected, an inlet portion for the first operation chamber and an outlet portion for the second operation chamber are closed and air flow is generated from the second operation chamber to the first operation chamber by the pressure-adjusting mechanism. When carrying an object into an aseptic manipulation chamber, the object is housed in the first operation chamber and a first decontamination operation is performed, then the object is transferred to the second operation chamber and a second decontamination operation is performed.
    Type: Application
    Filed: January 7, 2015
    Publication date: November 24, 2016
    Applicant: SHIBUYA CORPORATION
    Inventors: Masaharu SHOMURA, Takuya FUNAZUKA
  • Publication number: 20160184814
    Abstract: An aseptic manipulation system comprises first and second operation chambers, an aseptic manipulation chamber, and a control unit. The control unit controls the ventilation of the first operation chamber for more than a first specified number of times, after an object is introduced into the first operation chamber, and ventilate the second operation chamber for more than a second specified number of times that is greater than the first specified number of times, after the object is transferred into the second operation chamber from the first chamber.
    Type: Application
    Filed: December 22, 2015
    Publication date: June 30, 2016
    Applicant: SHIBUYA CORPORATION
    Inventors: Takuya FUNAZUKA, Masaharu SHOMURA