Patents Assigned to SIGMAGRAFT, INC.
  • Patent number: 11008379
    Abstract: A method of preparing a purified collagen solution from porcine skin may include receiving and inspecting the porcine skin; treating the porcine skin with a sodium hydroxide treatment, resulting in a sodium hydroxide processed skin; treating the sodium hydroxide processed skin with an ethanol treatment, resulting in ethanol treated processed skin; producing liquid collagen from the ethanol treated processed skin; clarifying the liquid collagen; and concentrating the clarified liquid collagen.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: May 18, 2021
    Assignee: Sigmagraft, Inc.
    Inventors: Qi Wang, Dae Kyu Chang
  • Patent number: 9610381
    Abstract: A process is for extracting natural hydroxyapatite from bone in order to make granules for a bone graft. The process involves soaking and boiling raw bone cubes in deionized water. Soaking and boiling removes lipids, blood components, and proteins and creates bone cubes. Next, washing the bone cubes in deionized water and drying the bone cubes. Then, segregating cancellous bone cubes with densified porous structure from those without densified porous structure. After that, soaking the cancellous bone cubes with densified porous structure in a solution of sodium hydroxide and a solution of hydrogen peroxide. Next, washing the cancellous bone cubes with densified porous structure in deionized water and drying the bone cubes. Then, sintering the cancellous bone cubes with densified porous structure. After that, fracturing the cancellous bone cubes with densified porous structure into the granules for the bone graft.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: April 4, 2017
    Assignee: SIGMAGRAFT, INC.
    Inventors: Seung Hyun Lee, Yuni Pai, Katherine Park, Dae Kyu Chang
  • Publication number: 20150098875
    Abstract: A process is for extracting natural hydroxyapatite from bone in order to make granules for a bone graft. The process involves soaking and boiling raw bone cubes in deionized water. Soaking and boiling removes lipids, blood components, and proteins and creates bone cubes. Next, washing the bone cubes in deionized water and drying the bone cubes. Then, segregating cancellous bone cubes with densified porous structure from those without densified porous structure. After that, soaking the cancellous bone cubes with densified porous structure in a solution of sodium hydroxide and a solution of hydrogen peroxide. Next, washing the cancellous bone cubes with densified porous structure in deionized water and drying the bone cubes. Then, sintering the cancellous bone cubes with densified porous structure. After that, fracturing the cancellous bone cubes with densified porous structure into the granules for the bone graft.
    Type: Application
    Filed: October 8, 2013
    Publication date: April 9, 2015
    Applicant: SIGMAGRAFT, INC.
    Inventors: SEUNG HYUN LEE, YUNI PAI, KATHERINE PARK, DAE KYU CHANG