Abstract: The present disclosure relates to novel compounds of formulas (1) through (19) and to a method for treating humans infected with a virus including various respiratory viruses such as members of the Paramyxoviridae family (respiratory syncytial virus (RSV), human metapneumovirus (HMPV), human parainfluenza virus (HPIV), measles virus, and mumps virus) with a compound of formulas (1) through (19). The present disclosure also relates to a cytopathic effect (CPE)-based assay that will assess virus-induced CPE for screening of compounds for treating viral diseases or inhibiting a virus.
February 8, 2011
April 4, 2013
Sourthern Research Institute Office of Commercialization and Intellectual Prop.
Bill Severson, Dong Hong Chung, Colleen B. Jonsson, Ellie Lucile White, Lynn Rasmussen, Clinton Boykin Maddox, Subramaniam Ananthan, Ashish K. Pathak, Joseph A. Maddry