Patents Assigned to SRI International
  • Patent number: 10726846
    Abstract: An electronic device for providing health information or assistance includes an input configured to receive at least one type of signal selected from sound signals, verbal signals, non-verbal signals, and combinations thereof, a communication module configured to send information related to the at least one user and his/her environment to a remote device, including the sound signals, non-verbal signals, and verbal signals, the remote device being configured to analyze a condition of the at least one user and communicate condition signals to the electronic device, a processing module configured to receive the condition signals and to cause the electronic device to engage in a passive monitoring mode or an active engagement and monitoring mode, the active engagement and monitoring mode including, but not limited to, verbal communication with the at least one user, and an output configured to engage the at least one user in verbal communication.
    Type: Grant
    Filed: June 3, 2017
    Date of Patent: July 28, 2020
    Assignee: SRI INTERNATIONAL
    Inventors: Dimitra Vergyri, Diego Castan Lavilla, Girish Acharya, David Sahner, Elizabeth Shriberg, Joseph B Rogers, Bruce H Knoth
  • Patent number: 10722515
    Abstract: The disclosure generally relates to substituted purine analogs that are dual CLK2/CDK1 inhibitors or more potent and specific CLK inhibitors to target CLK2 and CDK1 kinases. These compounds may be useful in the treatment of germ-line mutations of the spliceosome leading to the development of cancers and other human disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: July 28, 2020
    Assignee: SRI International
    Inventors: Thomas R. Webb, Jaehyeon Park, Chandraiah Lagisetti
  • Patent number: 10719594
    Abstract: An example computing device includes a shares generation unit configured to generate secret shares of biometric information of a user; a storage interface configured to interface with storage nodes for storing each of the secret shares to a corresponding one of the storage nodes; and a computation engine configured to perform re-enrollment by outputting a plurality of messages to instruct each of the storage nodes to generate a respective share of a new helper data in accordance with the secret shares of the biometric information and a secure computation protocol, receive the respective share of the new helper data from two or more storage nodes, and determine the new helper data based on the respective share of the new helper data from each of the two or more storage nodes for subsequent authentication of the user, wherein the re-enrollment occurs without receiving additional/repeat biometric information, thereby resulting in faster re-enrollment.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: July 21, 2020
    Assignee: SRI International
    Inventor: Karim Eldefrawy
  • Patent number: 10711848
    Abstract: Methods and apparatus related to electrolaminate clutches and transmissions are disclosed. A device can include: an input shaft that can be coupled to an electrolaminate sheet; an output shaft that can be coupled rigidly to a spring positioned over the input shaft, where the spring includes a tab that fits a groove of a spring capture ring that can be positioned over the input shaft; and a drum connected to an electrical ground between the electrolaminate sheet and the spring capture ring, where the drum can be coupled rigidly to the spring capture ring. Then, when a voltage is applied to the electrolaminate sheet, the electrolaminate sheet can clamp to the drum and impart rotation of the input shaft to the drum. The imparted rotation can cause the spring capture ring and the spring to rotate and clamp down on the input shaft, imparting rotation to the output shaft.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: July 14, 2020
    Assignee: SRI International
    Inventors: Karen Shakespear Koenig, Pablo Eduardo Garcia Kilroy, Brian Keith McCoy, Allegra Anna Lenta Shum, Joseph Stephen Eckerle
  • Patent number: 10710247
    Abstract: Systems are provided for gripping or otherwise manipulating lettuce, sliced foodstuffs (e.g., sliced cheese, sliced tomato or other sliced vegetables), or other foodstuffs or other irregular objects or substances. These systems can facilitate the manipulation of groups of irregular objects, including distributing small amounts (e.g., individual instances) of such groups of objects. These systems operate to manipulate such objects by extending and retracting rods, wires, or otherwise-configured pins to contact and/or penetrate the object(s) to be manipulated. In some examples, the pins are retracted to individually dispense objects (e.g., slices of cheese) from a stack of objects. In some examples, the separation and angle of the pins can be controlled to, e.g., grip one or more irregular objects and subsequently to dispense some or all of the gripped object(s).
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: July 14, 2020
    Assignee: SRI International
    Inventors: Gordon Kirkwood, Murphy Kitchell
  • Patent number: 10706873
    Abstract: Disclosed are machine learning-based technologies that analyze an audio input and provide speaker state predictions in response to the audio input. The speaker state predictions can be selected and customized for each of a variety of different applications.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: July 7, 2020
    Assignee: SRI International
    Inventors: Andreas Tsiartas, Elizabeth Shriberg, Cory Albright, Michael W. Frandsen
  • Publication number: 20200197332
    Abstract: This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a ?2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a ?2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Applicants: The USA, as represented by the Secretary, Department of Health and Human Services, SRI International
    Inventors: Irving W. Wainer, Michel Bernier, Lawrence Robert Toll, Lucita Arenas Jimenez
  • Patent number: 10691743
    Abstract: A computing system for realizing visual content of an image collection executes feature detection algorithms and semantic reasoning techniques on the images in the collection to elicit a number of different types of visual features of the images. The computing system indexes the visual features and provides technologies for multi-dimensional content-based clustering, searching, and iterative exploration of the image collection using the visual features and/or the visual feature indices.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: June 23, 2020
    Assignee: SRI International
    Inventors: Harpreet Singh Sawhney, Jayakrishnan Eledath, Mayank Bansal, Bogdan C. Matei, Xutao Lv, Chaitanya Desai, Timothy Shields
  • Patent number: 10691900
    Abstract: A text analytics platform includes instructions embodied in one or more non-transitory machine accessible storage media configured to cause a computing device to retrieve text from at least one text source and implement one or more algorithms to determine a quantitative linguistics assessment for the retrieved text and provide as output a numeric value corresponding to the quantitative linguistics assessment. The quantitative linguistics assessment is based at least in part on a trained model.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: June 23, 2020
    Assignee: SRI International
    Inventors: John J. Niekrasz, Edmond D. Chow
  • Patent number: 10679063
    Abstract: A computing system for recognizing salient events depicted in a video utilizes learning algorithms to detect audio and visual features of the video. The computing system identifies one or more salient events depicted in the video based on the audio and visual features.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: June 9, 2020
    Assignee: SRI International
    Inventors: Hui Cheng, Ajay Divakaran, Elizabeth Shriberg, Harpreet Singh Sawhney, Jingen Liu, Ishani Chakraborty, Omar Javed, David Chisolm, Behjat Siddiquie, Steven S. Weiner
  • Patent number: 10670119
    Abstract: An apparatus includes a first ring having an open annular space and a variable-width groove disposed on an interior peripheral surface of the first ring; a second ring rotatable within the open annular space of the first ring, where the second ring has a respective variable-width groove disposed on an exterior peripheral surface of the second ring; and a plurality of rollers disposed between, and configured to roll on, the interior peripheral surface of the first ring and the exterior peripheral surface of the second ring and rotatable therebetween.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: June 2, 2020
    Assignee: SRI International
    Inventors: Alexander Steele Kernbaum, Curt Salisbury
  • Patent number: 10664625
    Abstract: A device includes a substrate, an array of metal pads on a first surface of the substrate, a carbon polymer composite covering the array of metal pads, the composite having variations that result in random resistance values between the metal pads usable as a random code. A method of manufacturing a secure device, including forming an array of metal pads on a dielet substrate, the dielet substrate containing at least one memory in which is stored an encryption key, and an RF communication section, covering the array of metal pads with a carbon polymer composite such that variations in the carbon concentration in the polymer forms a unique pattern of resistance, attaching the dielet substrate to a host component, receiving a request from a security server for a unique code determined by the unique pattern of resistance, and using the encryption key, encrypting and providing the unique code to the security server.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: May 26, 2020
    Assignee: SRI International
    Inventor: Michael G. Kane
  • Patent number: 10655670
    Abstract: An apparatus includes a housing that includes an inner space, an inlet connected to the inner space, and a plurality of outlets connected to the inner space. The housing allows an inner cable of a Bowden cable to pass therethrough such that the inner cable passes through the inlet, the inner space, and any of the plurality of outlets. The apparatus also includes an inner hub rotatably mounted in the inner space of the housing. The inner hub is configured to receive and guide the inner cable passing through the housing such that the inner cable forms a curved path about the inner hub. The apparatus includes a socket configured to receive the Bowden cable. The socket can be coupled to the housing at a plurality of different positions to select any of the plurality outlets such that the inner cable of the Bowden cable passes through the selected outlet.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: May 19, 2020
    Assignee: SRI International
    Inventors: Alexander Steele Kernbaum, Roy Kornbluh
  • Patent number: 10646471
    Abstract: The disclosure provides bisindole suitable for inhibiting lipoxygenases or A?-formation, and treating associated diseases, such as Alzheimer's disease. The bisindoles are indolo[2,3-b]carbazole derivatives, and may be administered to a patient as part of a pharmaceutical formulation.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: May 12, 2020
    Assignee: SRI International
    Inventor: Ling Jong
  • Publication number: 20200123170
    Abstract: Described herein are compounds, agents, compositions, and methods related to the treatment of a viral infection (e.g., Hepatitis C viral infection). In particular, the compounds, agents, compositions, and methods described herein inhibit viral entry into a target cell.
    Type: Application
    Filed: October 22, 2019
    Publication date: April 23, 2020
    Applicants: Trustees of Boston University, SRI International
    Inventors: John A. Porco, Jr., Wenhan Zhang, Tony Tianyi Wang, Shufeng Liu
  • Patent number: 10626453
    Abstract: Devices, systems and methods for the parallel detection of a set of distinct nucleic acid sequences use multiple sequence amplification and simultaneous hybridization readout. An automated nucleic acid analysis system comprises in microfluidic connection sample lysis, purification, PCR and detection modules configured to detect in parallel distinct nucleic acid sequences via multiple sequence amplification and simultaneous microarray hybridization readout. High performance microfluidic electroactive polymer (?EAP) actuators comprising a dead-end fluid chamber in which a surface of the chamber is an electrode covered with an EAP layer of dielectric elastomer are configured for particle sorting.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: April 21, 2020
    Assignee: SRI International
    Inventor: David E. Huber
  • Patent number: 10617654
    Abstract: This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a ?2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a ?2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: April 14, 2020
    Assignees: The USA, as represented by the Secretary, Department of Health and Human Services, SRI International
    Inventors: Irving W. Wainer, Michel Bernier, Lawrence Robert Toll, Lucita Arenas Jimenez
  • Patent number: 10620112
    Abstract: Devices, systems and methods detect latent HIV in a patient on anti-retroviral therapy (ART), the method comprising using optical scanning to identify in a cell sample of the patient Gag+ CD4 downregulated cells as in indication of latent HIV.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: April 14, 2020
    Assignees: SRI INTERNATIONAL, THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Lidia Sambucetti, Xiaohe Liu, Una O'Doherty
  • Patent number: 10617484
    Abstract: User interface devices are disclosed. The device can include a body that can be held in a user's hand. The body has an outer surface that can be gripped by fingers of the user's hand to facilitate translation and rotation of the body by the user's hand. The device can include one or snore sensors disposed within the body. In some embodiments, the one or more sensor can provide one or both of position and orientation information of the body to a control system. The body can provide feedback to the user via the exterior surface of the body that is gripped by the user's fingers and/or can receive control inputs from the user via one or more of translation of the body, rotation of the body, pressing of the outer surface with the user's fingers, and changing of the angular orientation of the longitudinal axis of the body. Methods of using a user interface device are also provided.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: April 14, 2020
    Assignee: SRI International
    Inventors: Pablo Eduardo Garcia Kilroy, Karen Shakespear Koenig, Jose Luis Cordoba Matilla, Joan Savall
  • Patent number: 10610858
    Abstract: A material includes a porous particle that includes a metal ion imprinted polymer. The metal ion imprinted polymer is formed from a hydrophilic co-monomer, a metal containing polymerizable compound, and a cross-linking agent. The metal containing polymerizable compound includes at least one metal chelating ligand. The metal ion imprinted polymer includes a plurality of metal ion selective binding sites. A method includes flowing brine containing a metal ion through a reactor that includes the material. The method further includes discharging the brine from the reactor, contacting the porous particles with water, and pressurizing the reactor with carbon dioxide. The carbon dioxide reacts with the adsorbed metal ions to form a metal carbonate solution. The method further includes depressurizing the reactor to precipitate metal carbonate from the metal carbonate solution and discharging the metal carbonate solution from the reactor.
    Type: Grant
    Filed: February 18, 2019
    Date of Patent: April 7, 2020
    Assignee: SRI International
    Inventors: Marc Hornbostel, Susanna Ventura, Srinivas Bhamidi