Patents Assigned to Straus Holdings Inc.
  • Publication number: 20120149007
    Abstract: The invention provides an improved method for sensitive and specific detection of target molecules, cells, or viruses. The inventive method uses large area imaging to detect individual labeled targets complexed with a target-specific selection moiety. The invention eliminates wash steps through the use of target-specific selection through one or more liquid layers that can contain optical dye and density agents. By eliminating washes the invention simplifies instrumentation engineering and minimizes user steps and costs. The invention uses sensitive image analysis to enumerate individual targets in a large area, is scalable, and can be deployed in systems ranging in complexity from manual to highly automated.
    Type: Application
    Filed: September 24, 2009
    Publication date: June 14, 2012
    Applicant: Straus Holdings Inc.
    Inventors: Ezra Abrams, Sadanand Gite, Lisa Shinefeld, Don Straus, Gordon Siek, Greg Yantz
  • Publication number: 20120046203
    Abstract: The invention provides analyzers that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient and specific selection and sensitive imaging detection of individual microscopic targets at low magnification. Automated embodiments allow efficient walk-away, on-demand, random-access high-throughput testing. The analyzers perform tests without requiring wash steps thus streamlining engineering and lowering costs. Thus, the invention provides analyzers that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests for analytes.
    Type: Application
    Filed: September 24, 2009
    Publication date: February 23, 2012
    Applicant: Straus Holdings Inc.
    Inventors: Bruce Walsh, Boris Blanter, Matthew Barra, Brian Connolly, Greg Yantz, Paul Gervasio, Don Straus
  • Patent number: 8021848
    Abstract: The invention provides efficient methods for rapidly and sensitively identifying cellular and viral targets in medical, industrial, and environmental samples. The invention labels targets and then detects them using large area imaging. Diagnostic tests based on the invention can be rapid, ultrasensitive, quantitative, multiplexed, and automated. The tests minimize sample preparation and do not require nucleic acid amplification or cell culture. A broad range of cells and viruses can be detected by the tests. Tests based on the invention can deliver the high level sensitivity of nucleic acid amplification tests, the user-friendliness, and speed of immunoassays, as well as the cost effectiveness and quantification offered by microbiological tests. The invention embodies the best attributes of the current diagnostic technologies, while addressing gaps in the diagnostic repertoire.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: September 20, 2011
    Assignee: Straus Holdings Inc.
    Inventor: Don Straus