Abstract: Particular disclosed embodiments disclosed herein concern using a one or more various mass tags, which can be specifically deposited at targets through direct or indirect enzymatic-catalyzed transformation, to provide a method for identifying targets in tissue samples. The mass tags may be labeled with stable isotopes to produce mass tags having the same chemical structure but different masses. Mass codes produced by ionizing the mass tags are detected and/or quantified using mass spectrometry. The method can be used for multiplexed detection of multiple targets in a particular sample. In some embodiments, a map divided into sections representing sections of the tissue sample may be prepared, with the map sections including data corresponding to quantification data wherein the size of a mass peak is determined and correlated with the amount of a target for the corresponding tissue sample section.

Abstract: In order to avoid writing duplicates of blocks of data into a storage platform, any virtual disk within the storage platform may have a de-duplication feature enabled. Or, all virtual disks have this feature enabled. For virtual disks with de-duplication enabled, a unique message digest is calculated for every block of data written to that virtual disk. Upon a write, these message digests are consulted in order to determine if a particular block of data has already been written, if so, it is not written again, and if not, it is written. All de-duplication virtual disks are written to a single system virtual disk within the storage platform. De-duplication occurs over the entire storage platform and over all its virtual disks because all message digests are consulted before a write is performed for any virtual disk. A read for a de-duplication virtual desk reads from the system virtual disk.

Abstract: The present disclosure is directed to modular microgrids and more particularly to core modules that comprise self-synchronizing devices that can connect and self-synchronizes voltage, frequency and phase with other power sources. The disclosed embodiments enable a modular power system to serve as the primary or secondary source of power for applications requiring loads from a few kilowatts (KW) to the scale of megawatts (MW). The modular system is generalized to use either a single or multiple power generation sources at once, with the ability to connect and self-synchronize voltage, frequency, and phase of a variety of different types of power sources. Power control systems designed to function with self-synchronizing technology enable a modular power system to satisfy a wide variety of needs and enable new features of resiliency and expandability.

Abstract: A microprocessor includes a load/store unit that performs store-to-load forwarding, a PIPT L2 set-associative cache, a store queue having store entries, and a load queue having load entries. Each L2 entry is uniquely identified by a set index and a way. Each store/load entry holds, for an associated store/load instruction, a store/load physical address proxy (PAP) for a store/load physical memory line address (PMLA). The store/load PAP specifies the set index and the way of the L2 entry into which a cache line specified by the store/load PMLA is allocated. Each load entry also holds associated load instruction store-to-load forwarding information. The load/store unit compares the store PAP with the load PAP of each valid load entry whose associated load instruction is younger in program order than the store instruction and uses the comparison and associated forwarding information to check store-to-load forwarding correctness with respect to each younger load instruction.

Abstract: Systems and methods for managing refresh rates of applications running on a display device are disclosed. A computing device is designed to monitor and slow/reduce refresh rates for some applications running on the display device, while also allowing other applications to run at a fast/increased refresh rate. Each application is associated with a target device (e.g., server). The computing device can regulate a continuous stream of data, allowing some applications to access the data, while limiting/preventing other applications from accessing the data. The applications with access to the data can run at the fast refresh rates, while the remaining applications update at the slow refresh rates. As a result, the applications running at the fast refresh rates allow a user viewing the display device to actively monitor the respective servers associated with the fast-running applications, while reducing network load based on the relatively slow-running applications.

Abstract: A very high resolution sensor for detecting an angular rotation of a rotating target, the sensor including a first pair of Hall effect sensors and a second pair of Hall effect sensors. A first magnetic flux density differential of the rotating target is generated from the first pair of Hall effect sensors and a second magnetic flux density differential of the rotating target is generated from the second pair of Hall effect sensors. A pulse corresponding to an amount of angular rotation of the rotating target is output based on the second magnetic flux density differential reaching the first magnetic flux density differential.

Abstract: Computing units provided at local sites or edge locations are programmed to execute conversational tools that generate pertinent, domain-specific responses to queries received from workers at such sites or locations. The conversational tools are large language models that are trained with domain-specific knowledge documents. Data representing queries are received from workers at such sites or locations and provided as inputs to the conversational tools along with text representing nearest knowledge documents from a knowledge base associated with the domain, as well as contextual data. Responses identified based on outputs received from the conversational tools in response to the inputs are provided to the workers that generated the queries.

Abstract: A method for video frame analysis includes determining a first dissimilarity metric and a second dissimilarity metric. The first dissimilarity metric may correspond to a first difference between a first foreground of a first key frame in a video and a second foreground of a second key frame following the first key frame in the video. The second dissimilarity metric may correspond to a second difference between the second foreground of the second key frame and a third foreground of a third key frame following the second key frame in the video. A playback of the video may be generated based on the first dissimilarity metric and the second dissimilarity metric. Related systems and computer program products are also provided.

Abstract: This disclosure provides techniques for managing memory which match per-data metrics to those of other data or to memory destination. In one embodiment, wear data is tracked for at least one tier of nonvolatile memory (e.g., flash memory) and a measure of data persistence (e.g., age, write frequency, etc.) is generated or tracked for each data item. Memory wear management based on these individually-generated or tracked metrics is enhanced by storing or migrating data in a manner where persistent data is stored in relatively worn memory locations (e.g., relatively more-worn flash memory) while temporary data is stored in memory that is less worn or is less susceptible to wear. Other data placement or migration techniques are also disclosed.

Abstract: The system can include a dispatcher and a plurality of cars. However, the system 100 can additionally or alternatively include any other suitable set of components. The system 100 functions to enable platooning of the plurality of cars (e.g., by way of the method S100).

Abstract: A firing circuit for operating an exploding foil initiator that employs a transistor to control the transmission of electrical energy from an electrical energy storage device to a bridge of the exploding foil initiator.

Abstract: An orthodontic bracket and archform system that uses friction-free mechanics are disclosed. The archform can have a male fastener that can be retained within an orthodontic bracket. The orthodontic bracket can have varying locking mechanism, such as deflectable tabs, springs, locking pins, and others, that can cooperate with features of the male fastener to prevent sliding between the archform and the bracket.

Abstract: A system for providing integrated detection and deterrence against an unmanned vehicle including but not limited to aerial technology unmanned systems using a detection element, a tracking element, an identification element and an interdiction or deterrent element. Elements contain sensors that observe real time quantifiable data regarding the object of interest to create an assessment of risk or threat to a protected area of interest. This assessment may be based e.g., on data mining of internal and external data sources. The deterrent element selects from a variable menu of possible deterrent actions. Though designed for autonomous action, a Human in the Loop may override the automated system solutions.

Abstract: Stents are disclosed herein. The stents described herein can comprise a hollow cylindrical body in which a middle region extends to a first end and also extends to an opposing second end. The first end and the second end can each comprise a plurality of flanges, within which the flanges can have either similar or different characteristics, particularly physical profiles.

Abstract: New and innovative systems and methods for registration degradation correction for surgical procedures are disclosed. An example system includes a surgical marking pen including a first trackable target and a registration plate including a second trackable target. The system also includes a navigation camera and a processor configured to perform a pen registration that determines a transformation between a tip of the surgical marking pen and the first trackable target when the tip of the surgical marking pen is placed on the registration plate. The pen registration enables the processor to record virtual marks at locations of the pen tip that correspond to physical marks drawn by the pen. Locations of the virtual marks are later compared to images of the physical marks to correct any registration degradation by moving a surgical camera or robotic arm connected to the surgical camera.

Abstract: This application relates to ransomware detection and data pruning management. Ransomware typically involves an I/O heavy process of encrypting data files and/or deleting or renaming the original files. Thus, ransomware attacks may be detected by analyzing the I/O activity in a given file system. In some embodiments, a software module running on a client machine manages copying, archiving, migrating, and/or replicating of primary data and restoring and/or pruning secondary data (e.g., backup copies of the primary data). When a potential ransomware attack is detected, the software module is immediately stopped so that the software module does not prune any data that may need to be restored. Upon receiving user input that indicates that the client machine is not under a ransomware attack, the software module is allowed to resume its operations, including pruning of the secondary data.

Abstract: Techniques for facilitating burn-in mitigation and associated imaging systems and methods are provided. In one example, a method applying a bias signal to a sensor array of an imaging device to increase a temperature of the sensor array to perform burn-in mitigation. The method further includes reducing the temperature of the sensor array. The method further includes determining whether a burn-in is present in the sensor array. Related systems and devices are also provided.

Abstract: The present invention relates to a physiological monitor and system, more particularly to an electroencephalogram (EEG) monitor and system, and a method of detecting the presence or occurrence of suppression in the EEG signal. Accurately detecting signal suppression in real-time provides the clinician with the ability to prevent possibly severe, long-term damage to patients as a result of excessive anesthetic or sedative. The present invention provides such a system and method for accurately and automatically detecting suppression in physiological, particularly EEG, signals in real-time and allowing for the administration of treatment or medication to reverse the effects of such situations, or minimize the harm caused. The present invention also allows for the use of closed-loop treatment or drug delivery systems to further automate the process and provide rapid treatment to a patient to reverse or minimize potential harm.

Abstract: The system 100 can include: a railroad integration system, a motion planner, a vehicle controller, an optional user interface (UI), an optional fleet management system, and an optional track data system. However, the system 100 can additionally or alternatively include any other suitable set of components. The system functions to facilitate vehicle control and/or manage authority within a rail network.