Patents Assigned to Technische Universitaet Dresden
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Patent number: 10519354Abstract: The invention relates to a hydrophobed porous oil binder in the form of a nonwoven fabric composed of lignocellulose-containing raw materials having a biologically functionalized surface for removing mineral-oil-based contaminants in seas, rivers, inland waters, and stormwater basins or wastewater treatment plants, wherein the density of the oil binder is 10 to 900 kg/m3, the oil binder is 1 to 25 mm thick, the broad surface of the oil binder has a dimension of 9 to 200 cm2, the porosity of the oil binder is 30 to 96%, measured with respect to the total fraction of the oil binder, and the flexural strength of the oil binder is at least 1.5 N/mm2.Type: GrantFiled: August 27, 2014Date of Patent: December 31, 2019Assignees: Technische Universitaet Dresden, Universitaet LeipzigInventors: Holger Unbehaun, Soren Tech, Swetlana Konig, Elena Safonova, Andre Wagenfuhr, Christian Wilhelm
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Patent number: 10521010Abstract: The invention relates to a system and a method for haptic interaction with virtual objects. The system of the invention is based on the idea that, for the haptic representation of any virtual three-dimensional object—synchronized with the visual representation—only the tangible haptic characteristics of the surface area of the object at the collision point or the area of contact are important. The haptic display system (morphling) of the invention that displays these characteristics comprises in principle three functional groups, which operate in synchronism with one another and with a visual subsystem. The individual subsystems can be operated statically or dynamically. In dynamic operation, users can change the position and/or shape, for example, of the tactile display by touching it. With regard to the real-time representation of the three-dimensional data of the user, at least the body part that is interacting with the object, e.g.Type: GrantFiled: August 18, 2017Date of Patent: December 31, 2019Assignee: TECHNISCHE UNIVERSITAET DRESDENInventors: Andreas Richter, Georgi Paschew, Uwe Marschner
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Publication number: 20190383782Abstract: Method and a device for the optical in ovo sex determination of fertilized and incubated birds' eggs. The method includes monitoring formation of at least one identifiable blood vessel, creating a hole in the shell of the egg, finding and irradiating the blood vessel with at least one laser beam source emitting an excitation wavelength, recording backscatter radiation of the irradiated blood vessel and evaluating backscatter radiation from recorded spectral intensity of fluorescence radiation in a spectral range redshifted to an excitation wavelength. Sex-specific properties of male and female blood are contained in the intensity and spectral profile of the recorded fluorescence radiation. where intensity levels for male blood has an evaluable value distinct from that of female blood. Further, determining the sex of the bird egg from difference values of the fluorescence intensity and displaying the sex determined for the embryo in the egg.Type: ApplicationFiled: March 20, 2017Publication date: December 19, 2019Applicant: TECHNISCHE UNIVERSITAET DRESDENInventors: Gerald STEINER, Grit PREUSSE, Roberta GALLI, Edmund KOCH
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Publication number: 20190351064Abstract: The present invention provides the modular design and assembly of novel targeting bio-conjugates, exclusively assembled by means of biotin-biotin binding element conjugation, comprising mono-biotinylated cell binding component, a tetrameric biotin-binding element, and mono-biotinylated payload for therapeutic and diagnostic purposes. In addition, there is provided a method of delivering the payload, such as therapeutic oligonucleotides, via mono-biotinylated targeting devices, such as antibodies or ligands, into eukaryotic cells by means of receptor-mediated endocytosis. The targeting bio-conjugates are suitable for use in the areas of medicine, pharmacy and biomedical research.Type: ApplicationFiled: October 27, 2017Publication date: November 21, 2019Applicant: TECHNISCHE UNIVERSITÄT DRESDENInventor: Achim TEMME
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Publication number: 20190339244Abstract: To determine the sex of a bird egg, a hole is produced at the blunt end of the bird egg, wherein the hole affects the calcareous shell and the outer shell membrane, whereas the inner shell membrane remains intact. In the region of the hole at the blunt end, beneath the intact inner shell membrane, at least one blood vessel is registered and the blood therein is excited by means of a preset incident radiation, the back-scattered radiation of which blood is measured, detected and evaluated for the sex determination.Type: ApplicationFiled: October 26, 2017Publication date: November 7, 2019Applicant: TECHNISCHE UNIVERSITAET DRESDENInventors: Gerald STEINER, Grit PREUSSE, Edmund KOCH, Roberta GALLI, Christian SCHNABEL
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Patent number: 10457895Abstract: A washing or cleaning agent that has MOFs (metal organic frameworks) in order to reduce offensive odor, a method for reducing malodors, and the use of MOFs to reduce malodors.Type: GrantFiled: December 21, 2017Date of Patent: October 29, 2019Assignees: Henkel AG & Co. KGaA, Technische Universität Dresden Fachbereich Anorganische Chemie IInventors: Christian Kropf, Matthias Sunder, Ursula Huchel, Peter Schmiedel, Marc Weyhe, Stefan Kaskel, Anja Guenther, Steffen Hausdorf
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Patent number: 10438515Abstract: The present invention relates to a labeling element for items, which on a surface thereof is formed with a plurality of pixels with periodic lattice structures, in particular linear lattice structures. Lattice structures with in each case one structural period ? and an alignment of the structural elements, which are aligned to one another in particular in a linear parallel manner, at an angle ? with respect to an axis of reference are formed in individual pixels such that when the pixels constituting the labeling element are irradiated with electromagnetic radiation, preferably monochromatic electromagnetic radiation, an image of the labeling element is created on an detector array or a surface, by means of images of at least one order of diffraction of the electromagnetic radiation diffracted by pixels which can be used for identification of the respective labeling element.Type: GrantFiled: June 8, 2017Date of Patent: October 8, 2019Assignees: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V., TECHNISCHE UNIVERSITAET DRESDENInventors: Andres Fabian Lasagni, Tim Kunze, Florian Roessler
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Publication number: 20190227152Abstract: A method and a fibre-optical system for illuminating and detecting an object by light includes in situ calibration of a fibre bundle and disturbance-corrected illumination or disturbance-corrected detection of an object, in particular for endoscopic and microscopic applications, and makes it possible to directly determine the single phase distortion of the light, caused by the transmission by the fibre bundle, in order to calibrate the fibre bundle, and thus provides a possibility for determining the system function of a fibre bundle that is improved compared with the prior art of measuring the double phase distortion. The system function is used for disturbance correction when illuminating or detecting the object.Type: ApplicationFiled: December 26, 2018Publication date: July 25, 2019Applicant: TECHNISCHE UNIVERSITÄT DRESDENInventors: Jürgen CZARSKE, Robert KUSCHMIERZ
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Patent number: 10347760Abstract: A reconfigurable field effect transistor (RFET) includes a nanowire, wherein the nanowire comprises two Schottky contacts, as well as two gate contacts partially enclosing the nanowire in cross section. An integrated circuit can be produced therefrom. The aim of producing CMOS circuits with enhanced functionality and a more compact design is achieved in that the nanowire is divided along the cross section thereof into two nanowire parts, wherein each nanowire part comprises a respective Schottky contact and a respective gate contact, and the two nanowire parts are connected electrically to one another via a common substrate and stand vertically on the substrate. In a nanowire-parts-array, between the nanowire parts, a respective top-gate contact and/or back-gate contact can be formed in a substrate defining a substrate plane.Type: GrantFiled: June 20, 2017Date of Patent: July 9, 2019Assignees: Technische Universität Dresden, NaMLab gGmbHInventors: Tim Baldauf, André Heinzig, Walter Michael Weber
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Publication number: 20190185809Abstract: The invention relates to a device for isolating stem cells from fetal tissues, which device has an incubation chamber, at least one pump, at least one reservoir for a tissue break-down solution, at least one reservoir for a rinsing solution, optionally a control unit, optionally a means for removing contaminants, and optionally a means for expansion of the isolated stem cells. The invention further relates to a method for isolating stem cells from fetal tissue, which method comprises, among other things, the mechanical dissociation and the enzymatic digestion of the fetal tissue and optionally density gradient centrifugation for removing contaminants. The device and the method according to the invention are particularly suitable for isolating mesenchymal stem cells from fetal tissues, such as umbilical cord tissue, placenta tissue, or fetal lung tissue.Type: ApplicationFiled: July 28, 2017Publication date: June 20, 2019Applicant: TECHNISCHE UNIVERSITÄT DRESDENInventors: Marius Alexander MÖBIUS, Mario RÜDIGER, Daniel FREUND
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Patent number: 10314109Abstract: Method for managing available communication resources in a communication network and node (100, 200) for a communication network The invention concerns a method for managing signaling duties in a communication network and a node for a communication network, the node comprising a resource management. The method comprises using at least one signaling duty concerning a requested service for allocating corresponding communication resource of one of the nodes (200), the signaling duty being assigned to a different, further node (100) and the one node (200) being capable for at least partly providing the service. The method further comprises using the one node and the further node for determining a compensation and providing the compensation to said one node.Type: GrantFiled: September 7, 2016Date of Patent: June 4, 2019Assignee: Technische Universität DresdenInventors: Eduard Jorswieck, Siddharth Naik, Janis Nötzel
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Publication number: 20190126387Abstract: The present invention relates to an apparatus and a method for the adaptive manufacturing of metallic components from a substrate (3) and a supporting element (1) which is to be applied to the substrate (3) and is to be connected in an integrally bonded manner to the substrate (3), with a supply device (7) which is configured to guide the supporting element (1) onto a surface to be coated of the substrate (3), and at least one laser light source (4) with which at least the surface of the supporting element (1) can be preheated directly before or at an impingement point or an impingement region between the supporting element (1) and the substrate (3) to a temperature suitable for the integrally bonded joining by means of an emitted laser beam (6). In addition, a rolling device (2) is provided which is equipped with at least one roll and is configured to press the heated supporting element (1) onto the substrate (3) and, in the process, to connect them in an integrally bonded manner to the substrate (3).Type: ApplicationFiled: April 7, 2017Publication date: May 2, 2019Applicants: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V., TECHNISCHE UNIVERSITAET DRESDENInventors: Volker FUX, Steffan BONSS, Marko SEIFERT, Andrea BERGER, Thomas FIEBIGER
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Patent number: 10219710Abstract: A device for adjusting and determining the blood flow plateau at a patient's limb, wherein the device includes an chamber the wall of which surrounds an inner space, and at least one opening for inserting at least a part of the limb into the inner space as well as at least one recess, that allows access to the part of the limb that is located inside the inner space, are formed in the chamber, and wherein the device includes at least one heating element that is in thermal contact with the inner space. In this context, it is provided that the device further includes an apparatus for determining the blood flow plateau at the part of the limb that is located inside the inner space.Type: GrantFiled: January 30, 2015Date of Patent: March 5, 2019Assignee: TECHNISCHE UNIVERSITÄT DRESDENInventors: Graeme Eisenhofer, Christina Pamporaki, Angelos Filippatos
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Publication number: 20190010541Abstract: The invention relates to a method and means for diagnosing tumors, in particular for an early diagnosis (prevention) and for differentiating between benign and malignant tumors using a PCR, in particular in bodily fluids. The method according to the invention is characterized by a combination of a pre-amplification process using a PCR, wherein methylated DNA sequences are amplified more strongly than non-methylated DNA sequences, and a subsequent quantification process using a special digital PCR, in which significantly more DNA is used than normally in the prior art. As comparison data indicates, the invention advantageously allows a clear reliable conclusion as to whether a malignant tumor disease is present or not. The invention is suitable for screening (prevention), monitoring the progress of a tumor disease, in particular to order to exclude a minimal residual disease (MRD), and for a differential diagnosis between malignant carcinoma and benign tumors.Type: ApplicationFiled: December 22, 2016Publication date: January 10, 2019Applicant: Technische Universität DresdenInventors: Mario MENSCHIKOWSKI, Albert HAGELGANS, Gabriele SIEGERT
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Patent number: 10150953Abstract: The present invention relates to a method for preparing an expression vector encoding a well-tolerated and highly specific tailored recombinase, which tailored recombinase is capable of recombining asymmetric target sequences within the long terminal repeat (LTR) of proviral DNA of a plurality of retrovirus strains which may be inserted into the genome of a host cell, as well as to the obtained expression vector, cells transfected with these, expressed recombinase and pharmaceutical compositions comprising the expression vector, cells and/or recombinase. Pharmaceutical compositions are useful, e.g., in treatment and/or prevention of retrovirus infection, in particular, HIV infection. In particular, the invention relates to well-tolerated and highly specific tailored recombinases capable of combining asymmetric target sequences in a more than 90% of HIV-strains, thereby excising the HIV-1 sequences, and expression vectors encoding them.Type: GrantFiled: September 1, 2015Date of Patent: December 11, 2018Assignees: Heinrich-Pette-Institut Leibniz-Institut für Experimentelle Virologie-Stiftung bürgerlichen Rechts, Technische Universität DresdenInventors: Joachim Hauber, Jan Chemnitz, Frank Buchholz, Janet Karpinski
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Patent number: 10139275Abstract: Apparatus for spectrometrically capturing light includes a wavelength-adjustable filter for converting spectral information into location information and an organic photodiode for converting the location information into electrical signals which can be forwarded, wherein the filter and the organic photodiode form a one-piece monolith, the organic photodiode is connected to the filter or the organic photodiode is integrated in the filter, the filter consists of at least one spectrally resolving element in the form of at least one layer-like photonic crystal which constitutes the monolith and in which two layers of variable thickness D are formed along a direction perpendicular to the incidence of light. A resonant layer is arranged between the two layers. The organic photodiode includes: a photoactive layer, a first electrode, and a second electrode sandwiching the photoactive layer, and one of the electrodes is in contact with the photonic crystal.Type: GrantFiled: October 7, 2015Date of Patent: November 27, 2018Assignee: TECHNISCHE UNIVERSITÄT DRESDENInventors: Maik Langner, Hartmut Fröb, Vadim G. Lyssenko, Markas Sudzius, Karl Leo
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Patent number: 10109387Abstract: What is presented here is a transparent electrode having: at least one carrier layer for stabilizing the electrode; at least one electrically conductive layer containing metal nanowires, which is produced by spreading a suspension of a liquid and the metal nanowires surrounded by a stabilizing layer, along the carrier layer and drying same by removing the liquid; and at least one functional organic layer formed along the carrier layer, which, while the electrically conductive layer dries, by an electrical interaction with the metal nanowires and/or with the stabilizing layers of the metal nanowires, changes an interaction between the metal nanowires and the stabilizing layers such that the result is a substance-to-substance bond between the metal nanowires.Type: GrantFiled: June 17, 2016Date of Patent: October 23, 2018Assignees: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V., Technische Universitaet DresdenInventors: Lars Mueller-Meskamp, Franz Selzer, Jan Ludwig Bormann, Nelli Weiss, Christoph Sachse, Nikolai Gaponik, Alexander Eychmueller
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Patent number: 10036839Abstract: A direction-selective interferometric optical filter for spectrometric devices, at least includes an arrangement of two layered one-dimensional photonic structures. Each of the two structures contains a defect layer, and each photonic structure has a dispersion function in the energy momentum space (E, kx, ky), wherein kx and ky are momentum components of transmitted photons of the photonic structures for a defined energy (frequency/wavelength) E in the energy momentum space. Both photonic structures have opposite interfaces which are at a plane-parallel distance from one another. In this case, the dispersion functions of both photonic structures cross or intersect in the energy momentum space and produce a cut set of rays of waves on the surfaces of the dispersion functions at a particular energy, wherein a ray of waves contains waves selectively chosen through the filter at an angle, while other waves are reflected by the filter at other angles.Type: GrantFiled: October 7, 2015Date of Patent: July 31, 2018Assignee: TECHNISCHE UNIVERSITÄT DRESDENInventors: Maik Langner, Hartmut Fröb, Vadim G. Lyssenko, Markas Sudzius, Karl Leo
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Publication number: 20180207160Abstract: The present invention relates to novel HSP27 inhibitors, in particular thymine derivatives according to general formula (VI), (VII) or (VII) and phenothiazine derivatives according to formula (V), and to their use as drugs for the selective inhibition of the heat shock protein HSP27 (HSPB1), in particular for use in the treatment of carcinomas or cystic fibrosis, said inhibitors having a particularly advantageous activity in the lower micromolar or sub-micromolar active ingredient concentration range with respect to HSP27.Type: ApplicationFiled: July 28, 2015Publication date: July 26, 2018Applicant: TECHNISCHE UNIVERSITAET DRESDENInventors: Michael Schroeder, Yixin Zhang, Joerg-Christian Heinrich, Joachim Haupt, Sainitin Donakonda, Petra Lennig
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Publication number: 20180198005Abstract: A method for detecting infrared electromagnetic radiation and for converting same into an electrical signal, an optoelectronic component, in particular an organic infrared detector for (near) infrared detection, and use thereof for detecting an electromagnetic signal in the wavelength range of 780 nm to 10 ?m, are provided.Type: ApplicationFiled: August 12, 2016Publication date: July 12, 2018Applicant: TECHNISCHE UNIVERSITÄT DRESDENInventors: Bernhard SIEGMUND, Koen VANDEWAL, Andreas MISCHOK, Johannes BENDUHN, Donato SPOLTORE, Christian KÖRNER, Karl LEO