Patents Assigned to Tel-Aviv University Future Technology Development L.P.
  • Lipidated glycosaminoglycan particles and their use in drug and gene delivery for diagnosis and therapy
    Patent number: 9526705
    Abstract: Lipidated glycosaminoglycan particles, prepared by reacting a glycosaminoglycan with at least one lipid to cross-link the carboxylic acid groups in the glycosaminoglycan with a primary amine in the lipid, are used to encapsulate drugs for use in the treatment of pathological conditions in an animal.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: December 27, 2016
    Assignee: TEL-AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P.
    Inventors: Rimona Margalit, Dan Peer
  • LIPIDATED GLYCOSAMINOGLYCAN PARTICLES AND THEIR USE IN DRUG AND GENE DELIVERY FOR DIAGNOSIS AND THERAPY
    Publication number: 20160113882
    Abstract: Lipidated glycosaminoglycan particles, prepared by reacting a glycosaminoglycan with at least one lipid to cross-link the carboxylic acid groups in the glycosaminoglycan with a primary amine in the lipid, are used to encapsulate drugs for use in the treatment of pathological conditions in an animal.
    Type: Application
    Filed: January 7, 2016
    Publication date: April 28, 2016
    Applicant: Tel-Aviv University Future Technology Development L.P.
    Inventors: Rimona MARGALIT, Dan PEER
  • Lipidated glycosaminoglycan particles and their use in drug and gene delivery for diagnosis and therapy
    Patent number: 9259474
    Abstract: Lipidated glycosaminoglycan particles, prepared by reacting a glycosaminoglycan with at least one lipid to cross-link the carboxylic acid groups in the glycosaminoglycan with a primary amine in the lipid, are used to encapsulate drugs for use in the treatment of pathological conditions in an animal.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: February 16, 2016
    Assignee: TEL-AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P.
    Inventors: Rimona Margalit, Dan Peer
  • Peptides and methods using same for diagnosis and treatment of amyloid-associated disease
    Patent number: 8993510
    Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: March 31, 2015
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventor: Ehud Gazit
  • Compositions for treating amyloid associated diseases
    Patent number: 8889729
    Abstract: Indole derivatives, compositions including same, and methods utilizing same for the treatment of amyloid associated diseases, such as type II diabetes mellitus, Alzheimer's dementia or diseases, systemic and localized amyloidosis, and prion-related encephalopathies are provided.
    Type: Grant
    Filed: June 6, 2010
    Date of Patent: November 18, 2014
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventors: Ehud Gazit, Tomer Cohen
  • Apparatus and method for estimating stroke volume of the heart using bio-impedance techniques
    Patent number: 8868175
    Abstract: A method of estimating stroke volume of the heart is described. In this method, the volume of the heart is estimated from electrical impedance data of the chest, at two different phases of the cardiac cycle. The stroke volume is estimated from the difference between the volumes estimated at the two phases.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: October 21, 2014
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventor: Shimon Arad (Abboud)
  • Peptides and methods using same for diagnosis and treatment of amyloid-associated disease
    Patent number: 8697634
    Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X—Y or Y—X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: April 15, 2014
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventor: Ehud Gazit
  • Apparatus and method for estimating stroke volume of the heart using bio-impedance techniques
    Patent number: 8694089
    Abstract: A method of estimating stroke volume of the heart is described. In this method, the volume of the heart is estimated from electrical impedance data of the chest, at two different phases of the cardiac cycle. The stroke volume is estimated from the difference between the volumes estimated at the two phases.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: April 8, 2014
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventor: Shimon Arad (Abboud)
  • APPARATUS AND METHOD FOR ESTIMATING STROKE VOLUME OF THE HEART USING BIO-IMPEDANCE TECHNIQUES
    Publication number: 20140046205
    Abstract: A method of estimating stroke volume of the heart is described. In this method, the volume of the heart is estimated from electrical impedance data of the chest, at two different phases of the cardiac cycle. The stroke volume is estimated from the difference between the volumes estimated at the two phases.
    Type: Application
    Filed: October 17, 2013
    Publication date: February 13, 2014
    Applicant: TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P.
    Inventor: Shimon ARAD (ABBOUD)
  • PEPTIDES AND METHODS USING SAME FOR DIAGNOSIS AND TREATMENT OF AMYLOID-ASSOCIATED DISEASE
    Publication number: 20130338076
    Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.
    Type: Application
    Filed: August 26, 2013
    Publication date: December 19, 2013
    Applicant: Tel Aviv University Future Technology Development L.P.
    Inventor: Ehud GAZIT
  • Method of screening for compounds that disaggregate amyloid aggregates
    Patent number: 8563273
    Abstract: A peptide comprising at least 5 amino acid residues and less than 15 amino acid residues, the peptide including an amino acid sequence as set forth in SEQ ID NO: 7 as well as pharmaceutical compositions, kits and methods for diagnosing and treating amyloid associated diseases.
    Type: Grant
    Filed: April 9, 2009
    Date of Patent: October 22, 2013
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventor: Ehud Gazit
  • Formulations of water insoluble or poorly water soluble drugs in lipidated glycosaminoglycan particles and their use for diagnostics and therapy
    Patent number: 8501237
    Abstract: The invention provides a formulation of water insoluble or poorly water soluble drugs encapsulated in lipidated glycosaminoglycan particles for targeted drug delivery.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: August 6, 2013
    Assignee: Tel-Aviv University Future Technology Development L.P.
    Inventors: Rimona Margalit, Noga Yerushalmi, Dan Peer, Ilia Rivkin
  • LIPIDATED GLYCOSAMINOGLYCAN PARTICLES AND THEIR USE IN DRUG AND GENE DELIVERY FOR DIAGNOSIS AND THERAPY
    Publication number: 20130095032
    Abstract: Lipidated glycosaminoglycan particles, prepared by reacting a glycosaminoglycan with at least one lipid to cross-link the carboxylic acid groups in the glycosaminoglycan with a primary amine in the lipid, are used to encapsulate drugs for use in the treatment of pathological conditions in an animal.
    Type: Application
    Filed: September 27, 2012
    Publication date: April 18, 2013
    Applicant: TEL-AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P.
    Inventor: TEL-AVIV UNIVERSITY FUTURE TECHNOLOGY
  • COMPOSITIONS AND METHODS USING SAME FOR TREATING AMYLOID-ASSOCIATED DISEASES
    Publication number: 20130078233
    Abstract: Compounds having one or more phenol moieties, derivatives thereof, compositions containing same and uses thereof for the treatment of amyloid-associated diseases are provided.
    Type: Application
    Filed: November 27, 2012
    Publication date: March 28, 2013
    Applicant: Tel Aviv University Future Technology Development L.P.
    Inventor: Tel Aviv University Future Technology Development
  • Compositions and methods using same for treating amyloid-associated diseases
    Patent number: 8372880
    Abstract: Compounds having one or more phenol moieties, derivatives thereof, compositions containing same and uses thereof for the treatment of amyloid-associated diseases are provided.
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: February 12, 2013
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventors: Ehud Gazit, Yair Porat
  • Lipidated glycosaminoglycan particles and their use in drug and gene delivery for diagnosis and therapy
    Patent number: 8277847
    Abstract: Lipidated glycosaminoglycan particles, prepared by reacting a glycosaminoglycan with at least one lipid to cross-link the carboxylic acid groups in the glycosaminoglycan with a primary amine in the lipid, are used to encapsulate drugs for use in the treatment of pathological conditions in an animal.
    Type: Grant
    Filed: February 13, 2009
    Date of Patent: October 2, 2012
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventors: Rimona Margalit, Dan Peer
  • FORMULATIONS OF WATER INSOLUBLE OR POORLY WATER SOLUBLE DRUGS IN LIPIDATED GLYCOSAMINOGLYCAN PARTICLES AND THEIR USE FOR DIAGNOSTICS AND THERAPY
    Publication number: 20120171261
    Abstract: The invention provides a formulation of water insoluble or poorly water soluble drugs encapsulated in lipidated glycosaminoglycan particles for targeted drug delivery.
    Type: Application
    Filed: March 14, 2012
    Publication date: July 5, 2012
    Applicant: Tel-Aviv University Future Technology Development L.P.
    Inventors: Rimona MARGALIT, Noga Yerushalmi, Dan Peer, Ilia Rivkin
  • APPARATUS AND METHOD FOR ESTIMATING STROKE VOLUME OF THE HEART USING BIO-IMPEDANCE TECHNIQUES
    Publication number: 20120150050
    Abstract: A method of estimating stroke volume of the heart is described. In this method, the volume of the heart is estimated from electrical impedance data of the chest, at two different phases of the cardiac cycle. The stroke volume is estimated from the difference between the volumes estimated at the two phases.
    Type: Application
    Filed: February 13, 2012
    Publication date: June 14, 2012
    Applicant: Tel Aviv University Future Technology Development L.P.
    Inventor: Shimon ARAD (ABBOUD)
  • 3-D microbatteries based on interlaced micro-container structures
    Patent number: 8187740
    Abstract: An electrical energy storage device (20,70) includes a substrate (22), which is formed so as to define a multiplicity of micro-containers separated by electrically-insulating and ion-conducting walls (32). A first plurality of anodes (A) is disposed in a first subset (24) of the micro-containers, and a second plurality of cathodes (C) is disposed in a second subset (26) of the micro-containers. The anodes and cathodes are arranged in an interlaced pattern.
    Type: Grant
    Filed: April 20, 2005
    Date of Patent: May 29, 2012
    Assignee: Tel Aviv University Future Technology Development L.P.
    Inventors: Menachem Nathan, Emanuel Peled, Diana Golodnitsky, Vladimir Yufit, Tania Ripenbein
  • Formulations of water insoluble or poorly water soluble drugs in lipidated glycosaminoglycan particles and their use for diagnostic and therapy
    Patent number: 8178129
    Abstract: The invention provides a formulation of water insoluble or poorly water soluble drugs encapsulated in lipidated glycosaminoglycan particles for targeted drug delivery.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: May 15, 2012
    Assignee: Tel-Aviv University Future Technology Development L.P.
    Inventors: Rimona Margalit, Noga Yerushalmi, Dan Peer, Ilia Rivkin