Patents Assigned to Thar Pharmaceuticals, Inc.
  • CRYSTALLIZATION METHOD AND BIOAVAILABILITY
    Publication number: 20170022227
    Abstract: Preparation and in vitro and in vivo characterization of novel forms of active pharmaceutical ingredients, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Application
    Filed: October 7, 2016
    Publication date: January 26, 2017
    Applicant: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen HANNA, Ning SHAN, Miranda L. CHENEY, David R. WEYNA, Raymond HOUCK
  • Crystalline forms
    Patent number: 9340565
    Abstract: Preparation and characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl) phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Grant
    Filed: November 23, 2011
    Date of Patent: May 17, 2016
    Assignee: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Paul K. Isbester, Xufeng Sun
  • Crystallization method and bioavailability
    Patent number: 9334296
    Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: May 10, 2016
    Assignee: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Raymond K. Houck
  • CRYSTALLIZATION METHOD AND BIOAVAILABILITY
    Publication number: 20160016982
    Abstract: Preparation and in vitro and in vivo characterization of novel forms of active pharmaceutical ingredients, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Application
    Filed: June 4, 2015
    Publication date: January 21, 2016
    Applicant: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen HANNA, Ning SHAN, Miranda L. CHENEY, David R. WEYNA, Raymond HOUCK
  • NOVEL ORAL FORMS OF A PHOSPHONIC ACID DERIVATIVE
    Publication number: 20150306116
    Abstract: Novel solution complexes of zoledronic acid are described which give rise to improved properties of zoledronic acid. The invention includes aqueous solution and molecular complexes of zoledronic acid with and optical isomers of asparagine, histidine, arginine and proline as well as pharmaceutical complexes containing them and methods of treatment using them.
    Type: Application
    Filed: March 13, 2015
    Publication date: October 29, 2015
    Applicant: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen HANNA, Ning SHAN, Miranda CHENEY, David R. WEYNA
  • Crystallization method and bioavailability
    Patent number: 9169279
    Abstract: Preparation and in vitro and in vivo characterization of novel forms of active pharmaceutical ingredients, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: October 27, 2015
    Assignee: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Raymond Houck
  • Crystalline molecular comlpexes of tadalafil
    Patent number: 9040535
    Abstract: Crystalline molecular complexes of tadalafil are disclosed. The crystalline molecular complexes include those of tadalafil and oxalic acid, tadalafil and 4-hydroxybenzoic acid, tadalafil and 3-phenylpropanoic acid, tadalafil and malonic acid, tadalafil and methylparaben, and tadalafil and propylparaben. Pharmaceutical compositions containing the crystalline molecular complexes are also disclosed.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: May 26, 2015
    Assignee: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna
  • Oral forms of a phosphonic acid derivative
    Patent number: 8980868
    Abstract: Novel solution complexes of zoledronic acid are described which give rise to improved properties of zoledronic acid. The invention includes aqueous solution and molecular complexes of zoledronic acid with and optical isomers of asparagine, histidine, arginine and proline as well as pharmaceutical complexes containing them and methods of treatment using them.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: March 17, 2015
    Assignee: Thar Pharmaceuticals, Inc.
    Inventors: Mazen Hanna, Ning Shan, Miranda Cheney, David Weyna
  • Crystallization method and bioavailability
    Patent number: 8933057
    Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl) phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: January 13, 2015
    Assignee: Thar Pharmaceuticals, Inc.
    Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Raymond K. Houck
  • CRYSTALLIZATION METHOD AND BIOAVAILABILITY
    Publication number: 20140107076
    Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Application
    Filed: March 14, 2013
    Publication date: April 17, 2014
    Applicant: THAR PHARMACEUTICALS, INC.
    Inventor: THAR PHARMACEUTICALS, INC.
  • CRYSTALIZATION OF PHARMACEUTICAL COMPOUNDS
    Publication number: 20140100233
    Abstract: Novel crystalline forms of tadalafil suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Application
    Filed: October 7, 2013
    Publication date: April 10, 2014
    Applicant: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen HANNA, Ning SHAN, Miranda L. CHENEY, David R. WEYNA
  • CRYSTALLIZATION METHOD AND BIOAVAILABILITY
    Publication number: 20140057875
    Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Application
    Filed: February 13, 2013
    Publication date: February 27, 2014
    Applicant: THAR PHARMACEUTICALS, INC.
    Inventor: THAR PHARMACEUTICALS, INC.
  • NOVEL CRYSTALLINE FORMS
    Publication number: 20130316982
    Abstract: Preparation and characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl) phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Application
    Filed: November 23, 2011
    Publication date: November 28, 2013
    Applicant: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Paul K. Isbester, Xufeng Sun
  • Crystalline molecular complex of tadalafil and methylparaben
    Patent number: 8586587
    Abstract: The invention relates to novel crystalline forms of tadalafil suitable for pharmaceutical compositions in drug delivery systems for humans. More particularly, the invention relates to crystalline molecular complexes of tadalafil and methylparaben.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: November 19, 2013
    Assignee: Thar Pharmaceuticals, Inc.
    Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna
  • Crystallization method and bioavailability
    Patent number: 8399023
    Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: March 19, 2013
    Assignee: Thar Pharmaceuticals, Inc.
    Inventors: Mazen Hanna, Ning Shan, Miranda Cheney, David Weyna, Raymond K. Houck
  • Method of creating crystalline substances
    Patent number: 8241371
    Abstract: Process for preparing a cocrystal of an active substance and a cocrystal former, the process involving precipitating the active substance and the cocrystal former together from solution or suspension, in the presence of a supercritical or near-critical fluid, in particular using a GAS, SAS, SEDS or SAS-EM process. The invention also provides a cocrystal prepared using such a process, and its use as a seed crystal in a subsequent process for precipitating a cocrystal of an active substance and a cocrystal former.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: August 14, 2012
    Assignee: Thar Pharmaceuticals, Inc.
    Inventors: Mazen Hanna, George Townend
  • CRYSTALLIZATION METHOD AND BIOAVAILABILITY
    Publication number: 20110028435
    Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.
    Type: Application
    Filed: July 30, 2010
    Publication date: February 3, 2011
    Applicant: THAR PHARMACEUTICALS, INC.
    Inventors: Mazen HANNA, Ning Shan, Miranda Cheney, David Weyna, Raymond K. Houck
  • METHOD OF CREATING CRYSTALLINE SUBSTANCES
    Publication number: 20080280858
    Abstract: Process for preparing a cocrystal of an active substance and a cocrystal former, the process involving precipitating the active substance and the cocrystal former together from solution or suspension, in the presence of a supercritical or near-critical fluid, in particular using a GAS, SAS, SEDS or SAS-EM process. The invention also provides a cocrystal prepared using such a process, and its use as a seed crystal in a subsequent process for precipitating a cocrystal of an active substance and a cocrystal former.
    Type: Application
    Filed: February 7, 2008
    Publication date: November 13, 2008
    Applicant: Thar Pharmaceuticals, Inc.
    Inventors: Mazen Hanna, George Townend