Patents Assigned to Thar Pharmaceuticals, Inc.
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Publication number: 20170022227Abstract: Preparation and in vitro and in vivo characterization of novel forms of active pharmaceutical ingredients, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: ApplicationFiled: October 7, 2016Publication date: January 26, 2017Applicant: THAR PHARMACEUTICALS, INC.Inventors: Mazen HANNA, Ning SHAN, Miranda L. CHENEY, David R. WEYNA, Raymond HOUCK
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Patent number: 9340565Abstract: Preparation and characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl) phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: GrantFiled: November 23, 2011Date of Patent: May 17, 2016Assignee: THAR PHARMACEUTICALS, INC.Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Paul K. Isbester, Xufeng Sun
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Patent number: 9334296Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: GrantFiled: March 14, 2013Date of Patent: May 10, 2016Assignee: THAR PHARMACEUTICALS, INC.Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Raymond K. Houck
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Publication number: 20160016982Abstract: Preparation and in vitro and in vivo characterization of novel forms of active pharmaceutical ingredients, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: ApplicationFiled: June 4, 2015Publication date: January 21, 2016Applicant: THAR PHARMACEUTICALS, INC.Inventors: Mazen HANNA, Ning SHAN, Miranda L. CHENEY, David R. WEYNA, Raymond HOUCK
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Publication number: 20150306116Abstract: Novel solution complexes of zoledronic acid are described which give rise to improved properties of zoledronic acid. The invention includes aqueous solution and molecular complexes of zoledronic acid with and optical isomers of asparagine, histidine, arginine and proline as well as pharmaceutical complexes containing them and methods of treatment using them.Type: ApplicationFiled: March 13, 2015Publication date: October 29, 2015Applicant: THAR PHARMACEUTICALS, INC.Inventors: Mazen HANNA, Ning SHAN, Miranda CHENEY, David R. WEYNA
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Patent number: 9169279Abstract: Preparation and in vitro and in vivo characterization of novel forms of active pharmaceutical ingredients, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: GrantFiled: August 6, 2012Date of Patent: October 27, 2015Assignee: THAR PHARMACEUTICALS, INC.Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Raymond Houck
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Patent number: 9040535Abstract: Crystalline molecular complexes of tadalafil are disclosed. The crystalline molecular complexes include those of tadalafil and oxalic acid, tadalafil and 4-hydroxybenzoic acid, tadalafil and 3-phenylpropanoic acid, tadalafil and malonic acid, tadalafil and methylparaben, and tadalafil and propylparaben. Pharmaceutical compositions containing the crystalline molecular complexes are also disclosed.Type: GrantFiled: October 7, 2013Date of Patent: May 26, 2015Assignee: THAR PHARMACEUTICALS, INC.Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna
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Patent number: 8980868Abstract: Novel solution complexes of zoledronic acid are described which give rise to improved properties of zoledronic acid. The invention includes aqueous solution and molecular complexes of zoledronic acid with and optical isomers of asparagine, histidine, arginine and proline as well as pharmaceutical complexes containing them and methods of treatment using them.Type: GrantFiled: July 30, 2010Date of Patent: March 17, 2015Assignee: Thar Pharmaceuticals, Inc.Inventors: Mazen Hanna, Ning Shan, Miranda Cheney, David Weyna
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Patent number: 8933057Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl) phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: GrantFiled: February 13, 2013Date of Patent: January 13, 2015Assignee: Thar Pharmaceuticals, Inc.Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Raymond K. Houck
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Publication number: 20140107076Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: ApplicationFiled: March 14, 2013Publication date: April 17, 2014Applicant: THAR PHARMACEUTICALS, INC.Inventor: THAR PHARMACEUTICALS, INC.
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Publication number: 20140100233Abstract: Novel crystalline forms of tadalafil suitable for pharmaceutical compositions in drug delivery systems for humans.Type: ApplicationFiled: October 7, 2013Publication date: April 10, 2014Applicant: THAR PHARMACEUTICALS, INC.Inventors: Mazen HANNA, Ning SHAN, Miranda L. CHENEY, David R. WEYNA
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Publication number: 20140057875Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: ApplicationFiled: February 13, 2013Publication date: February 27, 2014Applicant: THAR PHARMACEUTICALS, INC.Inventor: THAR PHARMACEUTICALS, INC.
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Publication number: 20130316982Abstract: Preparation and characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl) phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: ApplicationFiled: November 23, 2011Publication date: November 28, 2013Applicant: THAR PHARMACEUTICALS, INC.Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna, Paul K. Isbester, Xufeng Sun
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Patent number: 8586587Abstract: The invention relates to novel crystalline forms of tadalafil suitable for pharmaceutical compositions in drug delivery systems for humans. More particularly, the invention relates to crystalline molecular complexes of tadalafil and methylparaben.Type: GrantFiled: February 25, 2010Date of Patent: November 19, 2013Assignee: Thar Pharmaceuticals, Inc.Inventors: Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna
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Patent number: 8399023Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: GrantFiled: July 30, 2010Date of Patent: March 19, 2013Assignee: Thar Pharmaceuticals, Inc.Inventors: Mazen Hanna, Ning Shan, Miranda Cheney, David Weyna, Raymond K. Houck
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Patent number: 8241371Abstract: Process for preparing a cocrystal of an active substance and a cocrystal former, the process involving precipitating the active substance and the cocrystal former together from solution or suspension, in the presence of a supercritical or near-critical fluid, in particular using a GAS, SAS, SEDS or SAS-EM process. The invention also provides a cocrystal prepared using such a process, and its use as a seed crystal in a subsequent process for precipitating a cocrystal of an active substance and a cocrystal former.Type: GrantFiled: February 7, 2008Date of Patent: August 14, 2012Assignee: Thar Pharmaceuticals, Inc.Inventors: Mazen Hanna, George Townend
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Publication number: 20110028435Abstract: Preparation, in-vitro and in vivo characterization of novel forms of (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid, suitable for pharmaceutical compositions in drug delivery systems for humans.Type: ApplicationFiled: July 30, 2010Publication date: February 3, 2011Applicant: THAR PHARMACEUTICALS, INC.Inventors: Mazen HANNA, Ning Shan, Miranda Cheney, David Weyna, Raymond K. Houck
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Publication number: 20080280858Abstract: Process for preparing a cocrystal of an active substance and a cocrystal former, the process involving precipitating the active substance and the cocrystal former together from solution or suspension, in the presence of a supercritical or near-critical fluid, in particular using a GAS, SAS, SEDS or SAS-EM process. The invention also provides a cocrystal prepared using such a process, and its use as a seed crystal in a subsequent process for precipitating a cocrystal of an active substance and a cocrystal former.Type: ApplicationFiled: February 7, 2008Publication date: November 13, 2008Applicant: Thar Pharmaceuticals, Inc.Inventors: Mazen Hanna, George Townend