Patents Assigned to The Curators of the University of Missouri
  • Publication number: 20210050612
    Abstract: An electrochemical reaction cell comprising an anode electrode, a cathode electrode, and a membrane electrode assembly (MEA). The MEA is positioned between the anode electrode and the cathode electrode. The anode electrode, the cathode electrode, and the MEA each have a corrugated shape and are contained within a recess of a housing.
    Type: Application
    Filed: August 14, 2020
    Publication date: February 18, 2021
    Applicant: The Curators of the University of Missouri
    Inventor: Jonghyun Park
  • Patent number: 10920196
    Abstract: The present disclosure relates to methods for enhancing cultured meat production, such as livestock-autonomous meat production. In certain aspects, the meat is any metazoan tissue or cell-derived comestible product intended for use as a comestible food or nutritional component by humans, companion animals, domesticated or captive animals whose carcasses are intended for comestible use, service animals, conserved animal species, animals used for experimental purposes, or cell cultures.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: February 16, 2021
    Assignees: The Curators of the University of Missouri, Memphis Meats, Inc.
    Inventors: Nicholas J. Genovese, R. Michael Roberts, Bhanu Prakash V. L. Telugu
  • Patent number: 10924363
    Abstract: This disclosure relates to a resource management system of a computing network. The design of the resource management system is an edge-Internet of Things (IoT) framework based on blockchain and smart contracts. The resource management system integrates a permissioned blockchain to link the edge cloud resources with each account for an IoT device, resource usage, and behavior of the IoT device. The resource management system uses credit-based resource management to control the resource of the IoT device that can be obtained from the edge server. Smart contracts are used to regulate behavior of the IoT device and enforce policies.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: February 16, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Jianli Pan, Jianyu Wang
  • Patent number: 10921264
    Abstract: Utilizing microwave reflections to compare a reference device with counterfeit and/or aging devices under test. The reflection from the device under test varies based on certain properties, which results in each device having a unique and intrinsic electromagnetic signature. Comparisons of the electromagnetic signature of the device under test to the electromagnetic signature of a reference device enable evaluating the acceptability of the device under test.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: February 16, 2021
    Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: Mohammad Tayeb Ghasr, Reza Zoughi, Satyajeet Shinde, Sasi Jothibasu
  • Patent number: 10918629
    Abstract: The disclosure relates to the field of lymphedema therapy, more specifically, to a new pharmacological strategy to rescue the failed lymph pump system that can supplement, enhance or replace current therapies.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: February 16, 2021
    Assignee: The Curators of the University of Missouri
    Inventor: Michael John Davis
  • Patent number: 10914734
    Abstract: Compositions which comprise a gold nanoparticle, dithiolated diethylenetriamine pentaacetic acid (DTDTPA), and a thioctic acid terminated peptide, wherein the DTDTPA is directly linked to the gold nanoparticle surface via an Au—S bond, and wherein the thioctic acid terminated peptide is directly linked to the gold nanoparticle surface via an Au—S bond.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: February 9, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Raghuraman Kannan, Ajit Zambre, Anandhi Upendran
  • Patent number: 10905437
    Abstract: In one embodiment, a cutting guide is disclosed for use in a surgical procedure to removed damaged tissue from a patient and form a recipient site configured and dimensioned to receive a donor graft. The cutting guide includes a first arm that abuts a section of the damaged tissue to be removed, and a second arm including a hole and a slot that receives a cutting implement, the first arm and the slot defining a distance therebetween corresponding to a desired dimension of the recipient site. In another embodiment, a cutting guide is disclosed for use in forming a donor graft from donor tissue. The cutting guide includes a body that receives the donor tissue, and a shaping member that is rotatably secured to the body. The shaping member includes at least one vane that shapes the donor tissue so as to form the donor graft.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: February 2, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Ferris M. Pfeiffer, James L. Cook, James P. Stannard
  • Patent number: 10898563
    Abstract: The present disclosure provides a novel therapeutic vaccine approach that triggers a therapeutic antitumor response. The inventive approach is to selectively eliminate the carbohydrate sequences from tumor cells without affecting the tumor associated protein epitopes.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: January 26, 2021
    Assignee: The Curators of the University of Missouri
    Inventor: Gary Clark
  • Publication number: 20210017490
    Abstract: The present invention provides a novel oocyte maturation medium or/and embryo culture medium with a chemically defined supplement to produce matured oocytes at high efficiency. The inventive medium or supplement comprises three growth factors, namely, fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF), and insulin-like growth factor 1 (IGF-1) in a synergistic combination. Methods for oocyte and embryo culture are also provided.
    Type: Application
    Filed: June 3, 2020
    Publication date: January 21, 2021
    Applicant: The Curators of the University of Missouri
    Inventors: Ye Yuan, Lee D. Spate, Randall S. Prather, R. Michael Roberts
  • Patent number: 10881098
    Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: January 5, 2021
    Assignees: The Curators of the University of Missouri, The Trustees of Columbia University in the City of New York
    Inventors: James L. Cook, Clark T. Hung, Eric Lima, Aaron Stoker
  • Patent number: 10883113
    Abstract: The present invention provides a method and means to change fatty acid and ultimately triacylglycerol production in plants and algae. Methods of the invention comprise the step of altering the activity levels of the committed step for de novo fatty acid biosynthesis, acetyl-CoA carboxylases (ACCase). More specifically, methods of the invention directly enhance the activity of ACCase by down-regulating the biotin/lipoyl attachment domain containing (BADC) genes through biotechnology or selective breeding approaches.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: January 5, 2021
    Assignee: The Curators of The University of Missouri
    Inventors: Jay Thelen, Matthew Salie
  • Publication number: 20200402802
    Abstract: The present invention relates to various high quality n-type and p-type doped gallium-based semiconductor materials, electronic components incorporating these materials, and processes of producing these materials. In particular, The present invention relates processes to achieve high quality, uniform doping of a whole wafer or a thin layer of gallium-based semiconductor materials for various applications such as a vertical power transistor or diode.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 24, 2020
    Applicant: The Curators of the University of Missouri
    Inventors: Jae Wan Kwon, Quang Nguyen
  • Publication number: 20200400380
    Abstract: The present disclosure generally provides an oscillating heat pipe, wherein the oscillating heat pipe comprises a 3-phase working fluid that includes at least one liquid phase portion, at least one vapor phase portion, and at least one solid phase portion, wherein in addition to a phase change between liquid and vapor, there is also a phase change from solid to liquid during a heat transfer process involving the oscillating heat pipe.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 24, 2020
    Applicant: The Curators of the University of Missouri
    Inventors: Hongbin Ma, Michael Merwin, Adalberto Aviles, Tingting Hao
  • Publication number: 20200391294
    Abstract: A process for manufacturing metal-ceramic composite material powder comprising ball milling metal powder and ceramic nanoparticles to yield a metal-ceramic composite powder comprising ceramic nanoparticles embedded in a metal matrix powder particles; wherein the ball milling is performed using a ceramic milling media and a milling vessel having a ceramic interior surface. Metal matrix nanocomposite powders comprising ceramic nanoparticles imbedded in metal matrix powder particles; wherein the metal matrix powder particles have a spherical shape; wherein there is uniform distribution the ceramic nanoparticles; wherein the nanocomposite powders have good flowability.
    Type: Application
    Filed: June 15, 2020
    Publication date: December 17, 2020
    Applicant: The Curators of the University of Missouri
    Inventors: Lianyl Chen, Minglei Qu
  • Patent number: 10859536
    Abstract: A photoacoustic flow cell, the components of which may be made well in advance of conducting photoacoustic analysis, comprising (a) a chamber structure that defines a chamber, a chamber inlet, and a chamber outlet, and (b) a glass test structure, at least a portion of which is supported by the chamber structure and at least a portion of which is located in the chamber, wherein the test structure comprises an interior surface that defines a test passageway through which samples will be flowed when conducting the photoacoustic analysis.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: December 8, 2020
    Assignee: The Curators of the University of Missouri
    Inventors: Benjamin Samuel Goldschmidt, Kyle Rood, John Andrew Viator
  • Publication number: 20200377272
    Abstract: A beverage container lid comprising a body having drinking hole and an air hole, and a slide-seal automatic Open and Close retention mechanism that comprises a sealing arm pivotally connected to the body, a movement and position retention linkage structured and operable to move the sealing arm between an Opened and a Closed position, a control mechanism slidingly disposed within the body and operably connected to the movement and position retention linkage such that movement of the control mechanism will control movement of the sealing arm between the Opened and Closed positions, and a biasing device structured and operable to exert constant force on the sealing arm, such that force exerted by the biasing device in combination with the structure and operation of the movement and position retention linkage will selectively retain the sealing arm in the Opened position and in the Closed position.
    Type: Application
    Filed: June 1, 2018
    Publication date: December 3, 2020
    Applicant: The Curators of the University of Missouri
    Inventors: Hongbin Ma, Hao Bai, Michael Merwin, Christopher Vincent
  • Patent number: 10851096
    Abstract: Certain compounds of formula I: I and salts including pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: December 1, 2020
    Assignees: Rutgers, The State University of New Jersey, The Curators of the University of Missouri
    Inventors: William J. Welsh, Raymond Birge, Vladyslav Kholodovych, Youyi Peng, Thomas Walter Comollo, Stanley G. Kimani, Kamlendra Singh
  • Publication number: 20200365406
    Abstract: Doped nitride-based semiconductor materials and methods of producing these materials are described herein.
    Type: Application
    Filed: April 17, 2020
    Publication date: November 19, 2020
    Applicant: The Curators of the University of Missouri
    Inventors: Jae Wan Kwon, John Gahl, John Brockman
  • Patent number: 10827730
    Abstract: Non-human animals and offspring thereof comprising at least one modified chromosomal sequence in a gene encoding a CD163 protein are provided. Animal cells that contain such modified chromosomal sequences are also provided. The animals and cells have increased resistance to pathogens, including porcine reproductive and respiratory syndrome virus (PRRSV). The animals and offspring have chromosomal modifications of a CD163 gene. The invention further relates to methods of breeding to create pathogen-resistant animals and populations of animals made using such methods.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: November 10, 2020
    Assignee: The Curators of the University of Missouri
    Inventors: Randall S. Prather, Kevin D. Wells, Kristin M. Whitworth
  • Patent number: 10828720
    Abstract: An additive manufacturing system, method of manufacturing, and fabricated part. The system uses a material joining laser system to join together foil sheets to form a metal part. The material joining laser system can be configured to join adjacent foil sheets together in a substantially uniform manner. The manufacturing system also includes a material removal system that removes material from selected locations of the foil sheets to shape the foil sheets to correspond with selective slices of the part. The material removal system can be a laser system, such as a laser system configured to remove material from a foil sheet without removing material from an underlying layer. One embodiment involves the manufacture of amorphous alloy components.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: November 10, 2020
    Assignee: The Curators of the University of Missouri
    Inventors: Hai-Lung Tsai, Yiyu Shen, Yingqi Li, Chen Chen