Patents Assigned to The Flinders University of South Australia
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Patent number: 11882838Abstract: The present disclosure relates to bacterial inoculants, and methods for their use, to control a fungal root disease in a plant and promote plant growth in water limited conditions. In particular strains of Paenibacillus and Streptomyces are disclosed.Type: GrantFiled: April 27, 2018Date of Patent: January 30, 2024Assignee: The Flinders University of South AustraliaInventor: Christopher Milton Mathew Franco
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Publication number: 20230002502Abstract: The present disclosure relates to methods and products for reducing side effects associated with immunotherapy using immune agonist antibodies. In certain embodiments, the present disclosure provides a method of reducing one or more side effects associated with immunotherapy using an immune agonist antibody alone, or in combination with an immune checkpoint inhibitor, in a subject suffering from a cancer, the method comprising modifying the gut microbiota in the subject and thereby reducing the one or more side effects associated with the immunotherapy in the subject.Type: ApplicationFiled: November 26, 2020Publication date: January 5, 2023Applicants: South Australian Health and Medical Research Institute Limited, The Flinders University of South AustraliaInventors: David John Lynn, Stephen James Blake
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Patent number: 11445729Abstract: The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.Type: GrantFiled: August 15, 2019Date of Patent: September 20, 2022Assignee: The Flinders University of South AustraliaInventors: Christopher Milton Mathew Franco, Hoang Xuyen Le, Ross Alexander Ballard
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Patent number: 11425912Abstract: The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.Type: GrantFiled: August 13, 2019Date of Patent: August 30, 2022Assignee: The Flinders University of South AustraliaInventors: Christopher Milton Mathew Franco, Hoang Xuyen Le, Ross Alexander Ballard
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Publication number: 20210213053Abstract: A method of enhancing embryo implantation in a subject is disclosed which comprises administering to the uterine cavity of the subject a formulation comprising copper and/or zinc in an amount effective to stimulate endometrial production of leukaemia inhibitory factor (LIF) and/or vascular endothelial growth factor (VEGF). Alternatively, a device may be inserted into the uterine cavity of the subject, wherein the device comprises copper and/or zinc, for a period of time that is effective to stimulate endometrial production of LIF and/or VEGF. The method is suitable for use with women undergoing treatment by any of the assisted reproductive technologies, such as those involving the transfer of embryos such as in vitro fertilisation (IVF) and variants including IVF-ICSI (intracytoplasmic sperm injection) and in vitro maturation (IVM) treatments, as well as intrauterine-insemination (IUI) therapy.Type: ApplicationFiled: May 29, 2019Publication date: July 15, 2021Applicants: The Flinders University of South Australia, The University of MelbourneInventors: Kelton Paul Tremellen, David K. Gardner, Alexandra J. Harvey
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Publication number: 20210118525Abstract: The present disclosure relates to methods and systems for assessing the risk of glaucoma in a subject. In certain embodiments, the present disclosure provide a method of assessing the risk of primary open angle glaucoma in a subject, the method comprises determining a risk score for primary open angle glaucoma in the subject on the basis of the genetic content of the subject at a plurality of selected genetic loci or markers and thereby assessing the risk of primary open angle glaucoma in the subject, wherein the selected genetic loci or markers comprise (i) genetic loci or markers having an association with glaucoma, and/or (ii) genetic loci or markers having an association with increased intraocular pressure, and/or (iii) genetic loci or markers having an association with an increased vertical cup to disk ratio, and/or (iv) genetic loci or markers having an association with a multi-trait test of glaucoma, intraocular pressure and vertical cup to disc ratio. Other embodiments are described.Type: ApplicationFiled: June 20, 2019Publication date: April 22, 2021Applicants: The Flinders University of South Australia, The Council of the Queensland Institute of Medical Research, University of Tasmania, Southern Adelaide Local Health NetworkInventors: Jamie Evan Craig, Stuart MacGregor, Alex William Hewitt
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Patent number: 10647621Abstract: A method for the production of hydrocarbon(s), such as methane, substituted hydrocarbons, such as methanol, or the production of hydrogen, the method comprising the steps of contacting a first catalyst with water in order to photocatalyse the splitting of at least some of the water into hydrogen and oxygen; and contacting a second catalyst with a gas stream comprising carbon dioxide and at least some of the hydrogen produced from step (a) in order to photocatalyse the reaction between the hydrogen and carbon dioxide to produce hydrocarbon(s), such as methane, and/or substituted hydrocarbons, such as methanol. In an embodiment, the catalyst comprises gold and or ruthenium nanoclusters supported on a substrate.Type: GrantFiled: November 30, 2016Date of Patent: May 12, 2020Assignees: Adelaide Research and Innovation, The University of Adelaide, Flinders University of South Australia, University of Canterbury, University of South AustraliaInventors: Gregory F Metha, Gunther Andersson, Vladimir Golovko, Thomas Nann
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Patent number: 10596187Abstract: Provided herein are compositions, for example: oral rehydration compositions, beverages, food items, methods and uses, which utilise resistant starch to prevent or treat dehydration, including dehydration which is caused by diarrhoea. Beverages, food items and oral rehydration solutions including a resistant starch, which are suitable for aiding in the maintenance and restoration of hydration levels in individuals undertaking physical activities, including sports, are also disclosed.Type: GrantFiled: November 7, 2014Date of Patent: March 24, 2020Assignees: Yale University, Flinders University of South Australia, Balakrishnan Siddartha RamakrishnaInventors: Balakrishnan Siddartha Ramakrishna, Graeme Paul Young, Ian Lewis Brown, Henry Joseph Binder
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Publication number: 20200072842Abstract: A device for selective capture of target bladder cancer cells from urine or a urine derived fluid is provided. The device comprises a substrate having one or more cell capture surfaces, each cell capture surface comprising a functionalized film on the substrate and one or more target bladder cancer cell selective binding agents covalently bound to the functionalized film.Type: ApplicationFiled: April 12, 2018Publication date: March 5, 2020Applicants: University of South Australia, Flinders University of South AustraliaInventors: Krasimir Atanasov Vasilev, Melanie Macgregor, Jonathan Gleadle, Jordan Li
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Patent number: 10462990Abstract: The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.Type: GrantFiled: June 19, 2015Date of Patent: November 5, 2019Assignee: The Flinders University of South AustraliaInventors: Christopher Milton Mathew Franco, Hoang Xuyen Le, Ross Alexander Ballard
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Patent number: 10004660Abstract: A method for treating patients with sensor agnosia is described that uses a gaming system with a specialised two handed game controller that can provide isolated haptic feedback to the patient's hand that has the greatest sensory agnosia. The controller is designed to be easy to use for patients with limited dexterity and requires the user to use both hands to control the controller. The gaming system provides a range of interactive computer games that provide contextually relevant haptic feedback of varying durations and intensities. Haptic feedback is provided in response to events in a game, and whilst the controller requires two hands, each hand is vibrationally isolated so that haptic feedback is only provided to the desired hand. The system logs usage statistics of the patient and these can be sent back to a clinician for analysis. The system and controller is particularly suitable for children with Cerebral Palsy, but may be used to treat patients with sensory agnosia due to range of conditions.Type: GrantFiled: November 22, 2013Date of Patent: June 26, 2018Assignees: FLINDERS UNIVERSITY OF SOUTH AUSTRALIA, UNIVERSITY OF SOUTH AUSTRALIA, WOMEN'S AND CHILDREN'S HEALTH NETWORK INC.Inventors: David Anthony Hobbs, Susan Loris Hillier, Remo Nunzio Russo, Alexander William Walker, Max Bristow Hughes, Thomas Samuel Whitby
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Publication number: 20170215358Abstract: The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.Type: ApplicationFiled: June 19, 2015Publication date: August 3, 2017Applicant: THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIAInventors: Christopher Milton Mathew FRANCO, Hoang Xuyen LE, Ross Alexander BALLARD
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Patent number: 6773916Abstract: A method of treating an ocular disorder is disclosed, comprising administering to a patient in need of such treatment, an effective amount of a sub-immunoglobulin antigen-binding molecule that is immuno-interactive with a target antigen associated with the disorder. The invention is also directed to compositions comprising this sub-immunoglobulin antigen-binding molecule and to a method of diagnosing an ocular condition using such molecule.Type: GrantFiled: September 19, 2001Date of Patent: August 10, 2004Assignee: The Flinders University of South AustraliaInventors: Michael Alexander Thiel, Heddy Zola, Douglas John Coster, Keryn Anne Williams
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Patent number: 5578453Abstract: A synthetic or recombinant polypeptide displaying the antigenicity of all or an antigenic fragment of the H4 or H11 polypeptides of Toxoplasma gondii, and recombinant DNA molecules, vectors and host cells for the expression thereof. Use of the polypeptide in vaccine compositions and in diagnostic immunoassays is also disclosed.Type: GrantFiled: April 12, 1993Date of Patent: November 26, 1996Assignee: The Flinders University of South AustraliaInventors: Peter J. McDonald, Alan M. Johnson
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Patent number: 5501958Abstract: A process and a reagent for the determination of ions in fluids, wherein the influence of these ions on the activity of an enzyme is measured. The ions for example are sodium, potassium, calcium, magnesium, manganese, lithium, lead, zinc, copper, iron or other heavy metals or non-metallic ions comprising chloride, bicarbonate, protons, ammonium and substances that give rise to ammonium. The enzymes which are used may be a transferase, a hydrolase, an oxidoreductase or a lyase. An essential feature is a method to exclude interferences by ions by masking the interfering ions with a binding agent.Type: GrantFiled: September 19, 1994Date of Patent: March 26, 1996Assignees: Boehringer Mannheim GmbH, The Flinder University of South AustraliaInventors: Michael N. Berry, Michael-Harold Town, Georg-Burkhard Kresse, Uwe Herrmann
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Patent number: 5409814Abstract: A process and a reagent for the determination of ions in fluids, wherein the influence of these ions on the activity of an enzyme is measured. The ions for example are sodium, potassium, calcium, magnesium, manganese, lithium, lead, zinc, copper, iron or other heavy metals or non-metallic ions comprising chloride, bicarbonate, protons, ammonium and substances that give rise to ammonium. The enzymes which are used may be a transferase, a hydrolase, an oxidoreductase or a lyase. An essential feature is a method to exclude interferences by ions by masking the interfering ions with a binding agent.Type: GrantFiled: June 22, 1992Date of Patent: April 25, 1995Assignees: Boehringer Mannheim GmbH, The Flinders University of South AustraliaInventors: Michael N. Berry, Michael-Harold Town, Georg-Burkhard Kresse, Uwe Herrmann
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Patent number: 5384246Abstract: A process and a reagent for the determination of ions in fluids, wherein the influence of these ions on the activity of an enzyme is measured. The ions for example are sodium, potassium, calcium, magnesium, manganese, lithium, lead, zinc, copper, iron or other heavy metals or non-metallic ions comprising chloride, bicarbonate, protons, ammonium and substances that give rise to ammonium. The enzymes which are used may be a transferase, a hydrolase, an oxidoreductase or a lyase. An essential feature is a method to exclude interferences by ions by masking the interfering ions with a binding agent.Type: GrantFiled: June 22, 1992Date of Patent: January 24, 1995Assignees: Boehringer Mannheim GmbH, The Flinders University of South AustraliaInventors: Michael N. Berry, Michael-Harold Town, Georg-Burkhard Kresse, Uwe Herrmann
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Patent number: 5384247Abstract: A process and a reagent for the determination of ions in fluids, wherein the influence of these ions on the activity of an enzyme is measured. The ions for example are sodium, potassium, calcium, magnesium, manganese, lithium, lead, zinc, copper, iron or other heavy metals or non-metallic ions comprising chloride, bicarbonate, protons, ammonium and substances that give rise to ammonium. The enzymes which are used may be a transferase, a hydrolase, an oxidoreductase or a lyase. An essential feature is a method to exclude interferences by ions by masking the interfering ions with a binding agent.Type: GrantFiled: June 22, 1992Date of Patent: January 24, 1995Assignees: Boehringer Mannheim, GmbH, The Flinders University of South AustraliaInventors: Michael N. Berry, Michael-Harold Town, Georg-Burkhard Kresse, Uwe Hermann
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Patent number: 5380649Abstract: A process and a reagent for the determination of ions in fluids, wherein the influence of these ions on the activity of an enzyme is measured. The ions for example are sodium, potassium, calcium, magnesium, manganese, lithium, lead, zinc, copper, iron or other heavy metals or non-metallic ions comprising chloride, bicarbonate, protons, ammonium and substances that give rise to ammonium. The enzymes which are used may be a transferase, a hydrolase, an oxidoreductase or a lyase. An essential feature is a method to exclude interferences by ions by masking the interfering ions with a binding agent.Type: GrantFiled: June 22, 1992Date of Patent: January 10, 1995Assignees: Boehringer Mannheim GmbH, The Flinders University of South AustraliaInventors: Michael N. Berry, Michael-Harold Town, Georg-Burkhard Kresse, Uwe Herrmann
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Patent number: 4827075Abstract: A method of forming a support for use with a primary catalyst for conversion of a feed stream comprising carbon monoxide and hydrogen into hydrocarbons is disclosed.A primary catalyst and a method of manufacturing the catalyst is also disclosed.Furthermore, a secondary catalyst for the production of branched chain alkenes from straight chain alkenes is also disclosed, together with methods of manufacturing the secondary catalyst.Type: GrantFiled: June 17, 1988Date of Patent: May 2, 1989Assignee: The Flinders University of South AustraliaInventors: Bruce G. Baker, Neville J. Clark, Hamish McArthur, Edward Summerville