Patents Assigned to The Regents of the University of Colorado
  • Patent number: 10852294
    Abstract: The disclosure provides a method for quantification of hepatic function in a subject comprising measuring the clearance of an orally administered isotopically labeled cholic acid in a subject with, or suspected of having or developing, a hepatic disorder, for example, chronic hepatitis C. The disclosure further provides methods and kits for assessment of hepatic function.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: December 1, 2020
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventor: Gregory Thomas Everson
  • Patent number: 10851562
    Abstract: A passive continuity monitoring device is disclosed. This device can be used to protect a lock or other locking device and to indicate when a breach of the lock has occurred. The lock can include a connector with a magnet at one end spaced from an other magnet. The connector can be held in tension when the lock is engaged to maintain the spacing between the magnets. A breach in the loop of the system will cause the magnets to touch and complete a circuit. The completion of the circuit can trigger an alarm, can take a picture of the surrounding area, and can transmit a signal to interested parties.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: December 1, 2020
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventor: Aaron Park
  • Patent number: 10855203
    Abstract: A cascaded architecture composed of interconnected blocks that are each designed to process constant power and eliminate bulk energy storage are provided. Further, local controls within each block natively achieve both block- and system-level aims, making the system modular and scalable. Further methods of providing power conversion using such interconnected clocks are also provided.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: December 1, 2020
    Assignees: The Regents of the University of Colorado, a body corporate, Alliance for Sustainable Energy, LLC
    Inventors: Dragan Maksimovic, Prasanta Achanta, Brian B. Johnson, Miguel Rodriguez, Vahan Gevorgian
  • Publication number: 20200370203
    Abstract: Provided herein, in some embodiments, are methods and compositions for gene editing using a trackable gene library, for example, a barcoded and gene edited library.
    Type: Application
    Filed: February 4, 2019
    Publication date: November 26, 2020
    Applicant: The Regents of the University of Colorado, a Body Corporate
    Inventors: Kenneth Felsenstein, Dan Theodorescu, Ryan T. Gill
  • Publication number: 20200352424
    Abstract: A self-propelled semi- or fully-autonomous robotic endoscope device is provided that include multi-degrees of freedom movement and may be sensor-enabled for colonoscopy procedures. The device may include two independently controlled motors configured to drive micro-pillared treads above and below the device, allowing for 2-degrees of freedom (DOF) skid-steering even in a collapsed lumen. The robotic device contains similar functionality of a traditional endoscope, such as a camera, adjustable LEDs, channels for insufflation and irrigation, and a tool port for common endoscopy instruments (e.g., forceps, snares, etc.).
    Type: Application
    Filed: May 6, 2020
    Publication date: November 12, 2020
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Mark E. Rentschler, Gregory Formosa, Joseph M. Prendergast
  • Publication number: 20200352539
    Abstract: Various systems and methods for generating images are provided. In some embodiments, the techniques can include acquiring a medical image and an associated motion characterization. The motion characterization can then be used to generate a plurality of gated image data sets, sorted by phase in the motion cycle. A new amplitude-based motion characterization curve is derived from the association of phases with amplitude-based characteristics in the phase gated images. This newly derived amplitude-based motion characterization curve can then be used to re-sort data according to amplitude-based gating techniques known in the field or with data driven optimization techniques.
    Type: Application
    Filed: April 6, 2020
    Publication date: November 12, 2020
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventor: Adam Kesner
  • Patent number: 10829420
    Abstract: The invention provides filamentous organism-derived carbonaceous materials doped with organic and/or inorganic compounds, and methods of making the same. In certain embodiments, these carbonaceous materials are used as electrodes in solid state batteries and/or lithium-ion batteries. In another aspect, these carbonaceous materials are used as a catalyst, catalyst support, adsorbent, filter and/or other carbon-based material or adsorbent. In yet another aspect, the invention provides battery devices incorporating the carbonaceous electrode materials.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: November 10, 2020
    Assignees: The Regents of the University of Colorado, a body corporate, The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Zhiyong Ren, Mitchell Tyler Huggins, Justin C. Biffinger, Corey T. Love, Se-Hee Lee, Justin M. Whiteley
  • Patent number: 10829834
    Abstract: Systems and methods for recovering material from a gas phase are provided. Exemplary systems include a moving bed of particles onto which material can be deposited. The systems can operate in a continuous or semi-continuous mode.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: November 10, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO A Body Corporate
    Inventors: Alan W. Weimer, Aaron W. Palumbo, Illias Hischier, Arto J. Groehn, Boris A. Chubukov, Scott C. Rowe, Richard Fisher
  • Patent number: 10829672
    Abstract: The present invention relates to preparation and use of water dispersible nanogels and solvent dispersible reactive nanogels as additives to enhance polymer properties or as precursors to polymeric networks.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: November 10, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO
    Inventor: Jeffrey W. Stansbury
  • Patent number: 10830262
    Abstract: A phononic material and a method of using a phononic material for use in interacting with a fluid or solid flow are provided. The phononic material includes an interface surface and a subsurface feature. The interface surface is adapted to move in response to a pressure, and/or velocity gradients, associated with complex motion of a turbulent flow exhibiting a polarity of frequencies exerted on the interface surface. The subsurface feature extends from the interface surface. The subsurface feature comprises a phononic crystal or locally resonant metamaterial adapted to receive the pressure, and/or velocity gradients, from the turbulent flow via the interface surface and alter the phase and amplitude of a polarity of frequency components of the turbulent flow in order to reduce or increase the kinetic energy of the turbulent flow.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: November 10, 2020
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Mahmoud Hussein, Sedat Biringen
  • Patent number: 10812014
    Abstract: In various implementations, string inverter circuit configurations are provided that allow for increased device lifetimes. In one implementation, for example, an inverter includes a pair of inverter input terminals. A ground-balancing converter module is coupled between the pair of inverter input terminals and ground. The ground is disposed between each of the pair of inverter input terminals. A plurality of converter modules is coupled to an output of the ground-balancing converter module, each of the plurality of converter modules providing an output ac phase of the inverter. In another implementation, a method of controlling an inverter is provided. The method includes controlling a voltage level of each terminal of the pair of inverter input terminals to have equal magnitudes and opposite polarities with respect to a ground voltage.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: October 20, 2020
    Assignee: The Regents of the University of Colorado
    Inventor: Robert W Erickson
  • Patent number: 10807864
    Abstract: The invention includes a method of promoting interfacial mechanical bonding of two or more components through the use of suspended and/or freestanding structures fabricated using an atom-scale assembly process on at least a portion of the surfaces of such components.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: October 20, 2020
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Joseph J. Brown, Victor M. Bright
  • Publication number: 20200323658
    Abstract: Systems and methods for postural control of a multi-function prosthesis are provided. Various embodiments provide for a postural controller that use EMG signals to drive a point in a posture space and outputs continuously varying joint angles for a powered prosthetic hand. The postural controller can include an EMG signal processing unit to receive signals from electrodes for processing (e.g., band pass filtering, rectification, root mean square averaging, dynamic tuning, etc.). The processed EMG signals can then be combined or converted to produce a point in the postural control domain. The PC domain map defines the posture that corresponds to each PC cursor coordinate. This map can have limitless possible postures and limitless possible positions of the postures. The Joint Angle Transform converts the PC cursor coordinate into the joint angle array which is sent to the prosthetic hand thereby creating more natural movements.
    Type: Application
    Filed: April 27, 2020
    Publication date: October 15, 2020
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Jacob Segil, Richard Weir
  • Patent number: 10799511
    Abstract: The present invention includes compounds, compositions and methods for reducing or ameliorating mortality and/or morbidity due to chlorine inhalation.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: October 13, 2020
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventor: Livia A. Veress
  • Patent number: 10804672
    Abstract: A monolithic laser cavity (100, 200, 300, 400) for generating an output series of pulses (37) based on an input pump signal 36. This is achieved by a novel cavity design that utilizes a transparent, low-loss, and near zero-dispersion spacer (38) to form an optical resonator without the use of wave-guiding effects. The pulse forming material (32), optical elements (10-16, 30, 31, 33), and the laser gain medium (34) are in direct contact with the spacer and/or each other without any free-space sections between them. Therefore, the light inside the laser cavity never travels through free space.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: October 13, 2020
    Assignee: The Regents of the University of Colorado, a body
    Inventor: Thomas R Schibli
  • Publication number: 20200316645
    Abstract: The present invention relates to the unexpected discovery of novel methods of preparing nanodevices and/or microdevices with predetermined patterns. In one aspect, the methods of the invention allow for engineering structures and films with continuous thickness equal to or less than 50 nm.
    Type: Application
    Filed: May 25, 2017
    Publication date: October 8, 2020
    Applicants: The Regents of the University of Colorado, a Body Corporate, DRS Network & Imaging Systems, LLC
    Inventors: Steven M. GEORGE, Victor M. BRIGHT, Joseph J. BROWN, Jonas GERTSCH, Nathan Thomas EIGENFELD, George SKIDMORE
  • Patent number: 10791731
    Abstract: Systems for controlled freezing, storing and thawing a biological material in a bag and supporting apparatus. The systems are adapted to receive the biological material therein for freezing, storing, transporting and rapid thawing immediately prior to administration to a patient in need of the biological material.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: October 6, 2020
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Michael P. Chapman, Ernest Moore
  • Patent number: 10796403
    Abstract: An imaging system is provided. The imaging system includes a 3D image capture device, which is configured to capture a depth image of an object, and a thermal image capture device, which is configured to capture a thermal image of the object. The imaging system also includes a processing system, which is coupled with the 3D image capture device and the thermal image capture device. The processing system is configured to process the depth image and the thermal image to produce a thermal-depth fusion image by aligning the thermal image with the depth image, and assigning a thermal value derived from the thermal image to a plurality of points of the depth image.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: October 6, 2020
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Min-Hyung Choi, Shane Transue
  • Patent number: 10793851
    Abstract: Compositions and methods for tracking combinations of mutations in populations by coupling DNA assembly and paired-end sequencing technology with high-throughput sequencing. This allows for an unlimited number of mutation sites in a population of microorganisms to be identified, and allows sites to be sequenced across several replicates. Unique identifiers (DNA barcodes) can be used to measure fitness data by sequencing of the barcodes multiplexed with the mutation sites with high-throughput short sequencing read technology, allowing selections to be rapidly performed on populations of known combinatorial genotypes.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: October 6, 2020
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Ryan T. Gill, Ramsey Zeitoun
  • Patent number: 10794453
    Abstract: A miniturized laminar gear box possessing high torque densities and methods of manufacturing the same. The high torque density is possible by directing the output shaft of the planetary stages through the sun gear and behind the input shaft. This allows the input shafts of the planetary stages to face towards the interior of the gearbox and provides a rotary shaft for the spur stages housed in between the planetary stages.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: October 6, 2020
    Assignees: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE, COLORADO SCHOOL OF MINES
    Inventors: Richard Weir, Stephen Huddle, Barathwaj Murali, Ozkan Celik