Abstract: An exemplary system, method and computer-accessible medium for harmonizing neuromelanin (NM) data using combat directly on a NM database or using combat generated coefficients to harmonize future data can include, for example, receiving imaging information of a brain of the patient(s), from one MRI scanner, receiving imaging information of a brain of the patient(s), from a second MRI scanner and using combat to harmonize the data between scanners against a reference dataset. The Neuromelanin (NM) concentration of the patient(s) can then be determined based on the harmonized data. The NM concentration can be determined using a voxel-wise analysis procedure. The voxel-wise analysis procedure can be used to determine a topographical pattern(s) within a substantia nigra (SN) of the brain of the patient(s).
Type:
Application
Filed:
March 11, 2022
Publication date:
September 15, 2022
Applicants:
TERRAN BIOSCIENCES, INC., THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE RESEARCH FOUNDATION FOR MENTAL HEALTH HYGIENE, INC.
Inventors:
Samuel CLARK, Kenneth WENGLER, Guillermo HORGA HERNANDEZ
Abstract: This invention is directed to spermicidal or cytocidal activity of fatty acids and monoglycerides. More particularly, this invention is directed to the killing of sperm and cells by fatty acids and monoglycerides. The invention is also directed to spermicidal or cytocidal compositions consisting essentially of inert carrier and an effective amount of one or more compounds selected from the group consisting of fatty acids and monoglycerides thereof, fatty alcohols, and ether and lysophosphatidylcholine derivatives.
Type:
Grant
Filed:
May 28, 1993
Date of Patent:
November 14, 1995
Assignee:
Research Foundation For Mental Health Hygiene, Inc.
Inventors:
Charles E. Isaacs, Kwang S. Kim, Henryk M. Wisniewski