Abstract: The disclosure describes a method of reducing or preventing the growth of microbes on the surface of an object, wherein the object is of such material that it can act as a working electrode. The method comprises the steps of providing a counter electrode, and a reference electrode. The object is used as the working electrode. A first electrical current is passed through the working and counter electrodes. The first current through the counter electrode is varied such that a first electric potential of the working electrode is constant relative to the electric potential of the reference electrode. In some embodiments, a second electrical current is passed through the counter electrode such that a second electric potential of the working electrode is constant relative to the electric potential of the reference electrode.

Abstract: A method and system are disclosed for isolating intact acellular particles using size exclusion and for obtaining size and concentration of such isolated particles. In one embodiment, the disclosure is directed to use of Particle Purification Liquid Chromatography (PPLC), a high-resolution chromatographic size-guided turbidimetry-enabled system for dye-free isolation, on-line characterization, and retrieval of intact acellular particles, including extracellular vesicles (EVs) and membraneless condensate particles (MCs) from various biofluids.

Abstract: A breath-enhanced jet nebulizer is configured with a low liquid retention reservoir and a narrow liquid delivery passage to efficiently and efficiently aerosolize small drug volumes with minimal waste. Aerosol particles are directed through aerosol passage for delivery, although larger liquid particles are directed away from the aerosol outlet and recycled to the liquid reservoir.

Abstract: Provided are methods for detecting or diagnosing a traumatic brain injury or TBI by detecting concentration levels miRNAs associated with TBI in saliva. Methods for controlled and normalized comparisons of salivary miRNA concentration levels are further provided. Assay kits comprising salivary miRNAs, probes and/or primers for detecting salivary miRNAs are also provided.

Abstract: A photomultiplier containing a solid-state photoconductive film composed of amorphous selenium (a-Se) is provided. In the a-Se containing photomultiplier, a hole-blocking layer is provided that maximizes gain and maintains low dark conductivity. Also, the hole-blocking layer achieves reliable and repeatable impact ionization without irreversible breakdown. The hole-blocking layer is a non-insulating metal oxide having a dielectric constant (k) of greater than 10.

Abstract: The present invention provides a compound having the structure:

Abstract: A solar vapor generator system and method are provided. In some embodiments, the system has near perfect energy conversion efficiency in the process of solar vapor generation below room temperature. Remarkably, when the operation temperature of the system is below that of the surroundings, the total vapor generation will be higher than the upper limit that can be produced by the input solar energy.

Abstract: There is set forth herein an optoelectrical system comprising: a conductive path for supplying an input voltage to a photonics device, wherein the conductive path comprises a base structure through via extending through a substrate and a photonics structure through via, the photonics structure through via extending through a photonics device dielectric stack. There is set forth herein an optoelectrical system comprising: a second structure fusion bonded to an interposer base dielectric stack of a first structure. There is set forth herein a method comprising: fabricating a second wafer built structure using a second wafer, the second wafer built structure defining a photonics structure and having a photonics device integrated into a photonics device dielectric stack of the second wafer based structure; and wafer scale bonding the second wafer built structure to a first wafer built structure.

Abstract: A system and method of scheduling tasks, comprising receiving activity and performance data from registers or storage locations maintained by hardware and an operating system; storing calibration coefficients associated with the activity and performance data; computing an energy dissipation rate based on at least the activity and performance data; and scheduling tasks under the operating system based on the computed energy dissipation rate.

Abstract: The system, method, and computer readable medium described herein provide improvements in the ways that user interfaces present multi-dimensional relationships between data samples to a user. The disclosed user interface framework provides users with a visualization of the complex relationships between data samples having multi-dimensional attributes which allows the users to quickly and intuitively grasp the relationships between data samples for a large number of attributes at a glance and in a single data map visualization.

Abstract: A bidirectional AC power converter, having a front-end comprising parallel sets of three switches in series, which connects multi-phase AC to coupling transformer through a first set of tank circuits, for synchronously bidirectionally converting electrical power between the multi-phase AC and a DC potential, and for converting electrical power between the DC potential to a bipolar electrical signal at a switching frequency, controlled such that two of each parallel set of three switches in series are soft-switched and the other switch is semi-soft switched; the coupling transformer being configured to pass the bipolar electrical power at the switching frequency through a second set of the tank circuits to a synchronous converter, which in turn transfers the electrical power to a secondary system at a frequency different from the switching frequency.

Abstract: The present invention provides a compound having the structure: and use of the compound for inhibiting the growth of or killing a fungus.

Abstract: The present disclosure is directed to genetically modified carrier/donor cells that are engineered to be resistant to its oligonucleotide payload, and methods of delivering an oligonucleotide into a target cell. The disclosure is also directed to methods of treating cancer using the engineered carrier cells of the disclosure. An aspect of this disclosure is directed to engineering carrier cells to be resistant to the detrimental effects of an oligonucleotide.

Abstract: The present application provides flexible radio frequency (RF) assemblies, components thereof and related methods. The present application includes at least one flexible substrate comprising first and second sides, a flexible framework portion comprising a first material composition and a plurality of discrete spaced interior portions comprising second material compositions that differ from that of the flexible framework portion. The framework portion extends fully about a portion of each interior portion. The framework portion comprises a flexibility that is greater than that of the interior portions. Each interior portion and the framework portion comprise a dielectric constant, a loss tangent, a volume resistivity, a surface resistivity and a magnetic relative permeability. At least one of the dielectric constant, the loss tangent, the volume resistivity, the surface resistivity and the magnetic relative permeability of at least one of the interior portions differs from that of the framework portion.

Abstract: Post-copy is one of the two key techniques (besides pre-copy) for live migration of virtual machines in data centers. Post-copy provides deterministic total migration time and low downtime for write-intensive VMs. However, if post-copy migration fails for any reason, the migrating VM is lost because the VM's latest consistent state is split between the source and destination nodes during migration. PostCopyFT provides a new approach to recover a VM after a destination or network failure during post-copy live migration using an efficient reverse incremental checkpointing mechanism. PostCopyFT was implemented and evaluated in the KVM/QEMU platform. Experimental results show that the total migration time of post-copy remains unchanged while maintaining low failover time, downtime, and application performance overhead.

Abstract: Provided are functional segregated telodendrimers having, for example, two or three functional segments. The telodendrimers can have one or more crosslinking groups (e.g., reversible photocrosslinking groups). The telodendrimers can aggregate to form nanocarriers. Cargo such as drugs, imaging probes, and other materials may be sequestered in the core of the aggregates via non-covalent or covalent interactions with the telodendrimers. Such nanocarriers may be used in drug delivery applications and imaging applications.

Abstract: A system is provided for advanced health monitoring and diagnosis based on wearable nano-biosensing networks. Nanophotonic and wireless communication technologies are synergistically leveraged to bridge the gap between nano-biosensing technologies and commercial wearable devices. Embodiments of the presently-disclosed system may include: (1) a nanoplasmonic biochip, implanted subcutaneously and built on a flexible substrate; (2) a nanophotonic smart band or wearable device that is able to collect in-vivo signals on-demand and relay them wirelessly to the user's smartphone by means of a secure data transfer; and (3) advanced signal processing techniques implemented on a remote processor to extract relevant data from the received signals and provide a diagnosis in real-time.

Abstract: The invention provides a method of microbial control in water comprising adding to the water one or more bromine-based biocide(s) and cis-2-decenoic acid or a salt thereof. Compositions in the form of liquid concentrates comprising bromine-based biocides and cis-2-decenoic acid or a salt thereof are also described.

Abstract: Provided are compositions and methods for used in solubilizing, stabilizing and expressing proteins. The proteins are fusion proteins that contain a protein of interest. The fusion proteins contain segments of Ribose Binding Protein (RBP) or Maltose Binding Protein (MBP). The fusion proteins can have the RBP or MBP segments flanking the target protein, and the RBP or MBP segments can be in the fusion protein in the same orientation as they normally occur (except for being interrupted by the target protein) or the segments can be permuted. Novel segments of the RBP and MBP are provided and result in improved expression and/or solubility of the proteins. Some examples include one or a combination of two complete or partial Histidine tags. Some examples allow for the target protein to be separated from all or a part of the fusion protein such as by enzymatic or non-enzymatic cleavage.

Abstract: A device is provided that allows for repeated electrical connection of an integrated circuit. The device includes a top, an alignment plate, a connector and a bottom. The top, alignment plate, connector and bottom each have first and second sides facing opposite directions, with the top, alignment plate, connector and bottom being stacked in a vertical orientation. The top is vertically moveable relative to the alignment plate to secure the integrated circuit adjacent to an edge of the connector, with the edge extending from a space between the first and second sides thereof.