Patents Assigned to The Research Foundation, State University of New York at Buffalo
  • Patent number: 7125847
    Abstract: The present invention discloses a peptide of SEQ ID NO:2 and its variants that blocks stretch-activated ion channels. The peptide, designated as GsMTx-4, is present in the venom of the spider Grammostola spatulata. The present invention also discloses a method of purifying the peptide GsMTx-4 from the spider venom and a method for inhibition of stretch activated ion channels in a cell. The cDNA sequence encoding the GsMTx-4 is also disclosed. This peptide and its variants can be used for the treatment of cardiac arrhythmias.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: October 24, 2006
    Assignee: The Research Foundation of State University of New York at Buffalo
    Inventors: Frederick Sachs, Thomas Suchyna, Janice Johnson
  • Patent number: 6864090
    Abstract: The present invention provides a novel method for monitoring the reaction kinetics of the biodegradable polymers, and the surface concentration of a drug in a polymer blend matrix. Detailed information on surface concentration, degradation rates, degradation kinetics and mechanism, is provided by using Time-of-Flight Secondary Ion Mass Spectrometry (ToF SIMS) measurements. Also provided is a method for determining oligomers in hydrolyzed biodegradable polymers.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: March 8, 2005
    Assignee: Research Foundation of State University of New York at Buffalo
    Inventors: Joseph A. Gardella, Jr., Jiaxing Chen, Norma L. Hernandez de Gatica, Joo-Woon Lee
  • Publication number: 20010045069
    Abstract: An energy dissipation apparatus for installation in structural frames to mitigate seismic effects comprises a scissor-jack system of braces with an energy dissipation device such as a viscous, viscoelastic, or hysteretic damper, or an active or semi-active device, connected between opposing pivot joints of the scissor-scissor jack system. The scissor jack system magnifies displacement so that energy is dissipated more effectively by the damper. Open bay, diagonal, and alternative installation arrangements with respect a structural frame are disclosed.
    Type: Application
    Filed: March 28, 2001
    Publication date: November 29, 2001
    Applicant: The Research Foundation of the State University of New York at Buffalo
    Inventor: Michael C. Constantinou
  • Patent number: 5990041
    Abstract: This invention relates to a mesoporous carbon material in the form of filaments having a high surface area. A process is also provided to produce mesoporous carbon material of high surface area. The process comprises drying a carbon material, surface oxidizing the dried material, stabilizing the surface oxidized material, and activating the stabilized material to produce a highly activated, mesoporous material.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: November 23, 1999
    Assignee: Research Foundation of State University of New York at Buffalo
    Inventors: Deborah D. L. Chung, Weiming Lu
  • Patent number: 5788641
    Abstract: A device capable of providing non-invasive, accurate estimates of central venous pressure. This diagnostic device is particularly useful with patients suffering from cardiac disease.
    Type: Grant
    Filed: October 16, 1997
    Date of Patent: August 4, 1998
    Assignee: Research Foundation of State University of New York at Buffalo
    Inventors: Dennis C. Policastro, Robert E. Mates, Kenneth Peebles
  • Patent number: 5783141
    Abstract: An annular furnace capable of delivering precise temperature control. The furnace may also take the form of a toroid. The furnace may be employed in the heat treatment of many types of material including superconducting tape.
    Type: Grant
    Filed: August 4, 1995
    Date of Patent: July 21, 1998
    Assignee: The Research Foundation of State University of New York at Buffalo
    Inventors: Sushil N. Patel, Frederick C. Wong
  • Patent number: 5643670
    Abstract: The present invention relates to a particulate carbon complex made from a porous, particulate carbon substrate and a plurality of carbon filaments each having a first end attached to the porous, particulate carbon substrate and a second end distal from substrate. The complex is capable of transferring electrical current at a density of 350 to 10,000 mA/cm.sup.2 for a Fe.sup.+2 /Fe.sup.+3 oxidation/reduction electrochemical reaction couple carried out in an aqueous electrolyte solution containing 6 mM potassium ferrocyanide and 1M potassium nitrate. The complex is prepared by providing a porous, particulate carbon substrate with impregnated metal catalyst and contacting the substrate with a gaseous carbonaceous material under conditions effective to form a plurality of carbon filaments on the substrate. Generally, the complex includes particles of metal catalyst material at the end of the filaments distal from the substrate.
    Type: Grant
    Filed: July 29, 1993
    Date of Patent: July 1, 1997
    Assignee: The Research Foundation of State University of New York at Buffalo
    Inventor: Deborah D. L. Chung
  • Patent number: 5561102
    Abstract: A superconductive fullerene and a process for making such superconductive fullerene are provided. The process involves contacting a quantity of fullerene with the vapor of an interhalogen compound such as ICl. The halogen doped fullerenes exhibited a transition temperature above 60 K.
    Type: Grant
    Filed: December 14, 1994
    Date of Patent: October 1, 1996
    Assignee: The Research Foundation of State University of New York at Buffalo
    Inventors: Yi-Han Kao, Liwei Song, Deborah D. L. Chung, Kevin T. Fredette
  • Patent number: 5536686
    Abstract: A binder for binding reinforcement materials is provided in which an aluminum and/or Group IIa-containing compound is combined, in a liquid, with a phosphorus-containing compound wherein said binder has a ratio of phosphorus to aluminum and/or Group IIa ions of 14 to 34, preferably 20 to 30. The binder is useful in binding reinforcement materials, particularly suited for preparing preforms for making metal matrix composite materials.
    Type: Grant
    Filed: October 20, 1992
    Date of Patent: July 16, 1996
    Assignee: The Research Foundation of State University of New York at Buffalo
    Inventor: Deborah D. L. Chung
  • Patent number: 5535309
    Abstract: A neural network provides both linearly separable and non-linearly separable logic operations, including the exclusive-or operation, on input signals in a single layer of circuits. The circuit weights the input signals with complex weights by multiplication and addition, and provides weighted signals to a neuron circuit (a neuron body or some a) which provides an output corresponding to the desired logical operation.
    Type: Grant
    Filed: August 11, 1994
    Date of Patent: July 9, 1996
    Assignee: The Research Foundation, State University of New York at Buffalo
    Inventors: Yong-Chul Shin, Ramalingam Sridhar
  • Patent number: 5515455
    Abstract: A system for recognizing handwritten words of cursive script by extracting temporal information from static text is described. The temporal information consists of the shape, location and temporal sequence of the segments, or "primitives", constituting the word and is translated from bit maps images of the words into digital information format. By comparing the digital information with formatted digital information for a plurality of known words, as may be stored in computer memory, a list of words having a relatively high probability of matching the static text is generated, and used for word recognition by a process of selecting the most likely match.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: May 7, 1996
    Assignee: The Research Foundation of State University of New York at Buffalo
    Inventors: Venugopal Govindaraju, Dacheng Wang, Sargur Srihari
  • Patent number: 5484702
    Abstract: A method for preselecting a nucleic acid sequence of interest is provided. The method comprises immobilizing an affinity molecule to a solid support matrix, wherein the affinity molecule is specific for a hapten or target molecule; hybridization of a "hook" comprised of either an oligonucleotide (complementary to the sequence of interest) labeled with a hapten or target molecule to the target recombinant vector containing the nucleic acid sequence of interest; capturing of the vector-hook via the hapten or target molecule by the respective immobilized affinity molecule for which it has binding specificity; liberating the captured vector DNA by enzymatic digestion of either the hook, or of the immobilized affinity molecule; and adding and incubating competent host cells to promote the introduction of recombinant vector DNA into the competent host cells.
    Type: Grant
    Filed: January 27, 1994
    Date of Patent: January 16, 1996
    Assignee: Research Foundation of the State University of New York at Buffalo
    Inventor: Linda B. Ludwig
  • Patent number: 5455041
    Abstract: A method for inducing periodontal regeneration including soft tissue, cementum, and bone regeneration, resulting in a type of healing characteristic of the anatomy and architecture of the undiseased tissue, comprising treating the surface of the damaged root with a demineralizing agent, and then applying a growth factor directly to the treated bone surface.
    Type: Grant
    Filed: September 13, 1993
    Date of Patent: October 3, 1995
    Assignee: Research Foundation of State University of New York at Buffalo
    Inventors: Robert J. Genco, Moon-Il Cho
  • Patent number: 5380703
    Abstract: A superconductive fullerene and a process for making such superconductive fullerene are provided. The process involves contacting-a quantity of fullerene with the vapor of an interhalogen compound such as ICl. The halogen doped fullerenes exhibited a transition temperature above 60 K.
    Type: Grant
    Filed: January 25, 1993
    Date of Patent: January 10, 1995
    Assignee: The Research Foundation of State University of New York at Buffalo
    Inventors: Yi-Han Kao, Liwei Song, Deborah D. L. Chung, Kevin T. Fredette
  • Patent number: 5355436
    Abstract: A neural network provides both linearly separable and non-linearly separable logic operations, including the exclusive-or operation, on input signals in a single layer of circuits. The circuit weights the input signals with complex weights by multiplication and addition, and provides weighted signals to a neuron circuit (a neuron body or soma) which provides an output corresponding to the desired logical operation.
    Type: Grant
    Filed: October 5, 1992
    Date of Patent: October 11, 1994
    Assignee: The Research Foundation, State University of New York at Buffalo
    Inventors: Yong-Chul Shin, Ramalingam Sridhar
  • Patent number: 5321768
    Abstract: A system (method and apparatus) for handwritten character recognition recognizes characters within strings of text despite the presence of overlapping or disjointed characters. A string is segmented into discrete characters by removing noise and punctuation, joining the disconnected components of characters and splitting probable overlapping characters. After joining and splitting (as required), character recognition is performed to recognize characters in the string. Recognized characters are removed and the string is split in order that more characters can be recognized. If unrecognized characters remain in the string, the process is repeated. The joining and splitting operations are repeated until all subsequent characters in the string have been either recognized or determined to be unrecognizable.
    Type: Grant
    Filed: September 25, 1992
    Date of Patent: June 14, 1994
    Assignee: The Research Foundation, State University of New York at Buffalo
    Inventors: Richard K. Fenrich, Sargur N. Srihari
  • Patent number: 5248321
    Abstract: A process is provided for removing sulfur oxides from gaseous mixtures such as flue gases or tail gases. The process involves contacting the gaseous mixture with a non-functionalized polymeric sorbent which is essentially hydrophobic, such as styrenic polymers. The process may utilize pressure swing adsorption techniques, and is capable of producing a desorption stream with an SO.sub.2 concentration suitable for immediate conversion to elemental sulfur by the Claus process.
    Type: Grant
    Filed: August 6, 1992
    Date of Patent: September 28, 1993
    Assignee: The Research Foundation of State University of New York at Buffalo
    Inventor: Ralph T. Yang