Patents Assigned to The Trustees of the California State University
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Patent number: 11955263Abstract: Ferromagnetic materials are disclosed that comprise at least one Dirac half metal material. In addition, Dirac half metal materials are disclosed, wherein the material comprises a plurality of massless Dirac electrons. In addition, ferromagnetic materials are disclosed that includes at least one Dirac half metal material, wherein the material comprises a plurality of massless Dirac electrons, wherein the material exhibits 100% spin polarization, and wherein the plurality of electrons exhibit ultrahigh mobility. Spintronic devices and heterostructures are also disclosed that include a Dirac half metal material.Type: GrantFiled: November 4, 2022Date of Patent: April 9, 2024Assignee: The Trustees of the California State UniversityInventors: Nicholas Kioussis, Qilong Sun
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Publication number: 20240050549Abstract: A mammalian expression system comprising an attenuated, recombinant Ranavirus that has at least one foreign expression element using a unique combination of mammalian transcriptional and translational enhancement elements is disclosed. In other contemplated embodiments, a mammalian expression system comprising a virus, wherein the virus is engineered to express at least two vaccine antigens is disclosed. In addition, methods of delivering human antigens to a mammal are disclosed that include: providing a non-mammalian virus, engineering a recombinant virus that can express at least one foreign molecule by modifying the non-mammalian virus, and using the recombinant Ranavirus to express and deliver foreign antigens to a mammal.Type: ApplicationFiled: October 17, 2023Publication date: February 15, 2024Applicant: The Trustees of the California State UniversityInventors: James Jancovich, Nathan Bartlett
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Publication number: 20230277092Abstract: Contemplated systems for monitoring and analysis of human motion synthesis are disclosed herein that include: at least one garment configured to be worn by a user, at least one inertial sensor, wherein the at least one inertial sensor is integrated with or into the at least one garment, an information system, wherein the information system communicates with the at least one inertial sensor to produce a set of data, at least one musculorientation metric generated by the information system, and at least one performance report that is produced from the analysis of the at least one musculorientation metric.Type: ApplicationFiled: February 28, 2023Publication date: September 7, 2023Applicant: The Trustees of the California State UniversityInventors: Emel Demircan, I-Hung Khoo, Elliot Recinos
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Patent number: 11694575Abstract: Systems and methods for utilizing laboratory equipment in a hybrid reality environment or augmented virtual reality environment, are contemplated herein and include: at least one piece of laboratory equipment having at least one feature, wherein the at least one piece of laboratory equipment is tracked; a tracking module for tracking a position and an orientation of the at least one piece of tracked laboratory equipment; a virtual model, stored in a memory, comprising at least one 3-D virtual representation of the at least one feature of the at least one piece of laboratory equipment; and an experimentation module.Type: GrantFiled: April 15, 2019Date of Patent: July 4, 2023Assignee: The Trustees of the California State UniversityInventors: Kambiz Hamadani, Ali Ahmadinia, Xin Ye, Yuanyuan Jiang
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Patent number: 11636168Abstract: A system, methods and software for administering and managing experiential learning opportunities (ELOs) are disclosed. The system generally includes a database server storing a relational database containing ELO placement data and records and having an interface configured to communicate with a university computer having a student information database thereon, website server, configured to host an ELO website through which users interact with the relational database, and a memory in the website server, storing a content management system (CMS) that comprises modules and a data pool stored in/on storage nodes on the website server. The modules include a forms module for users to enter ELO data and submit ELO requests, ELO proposals, waivers and agreements, and a timelog module to collect and store timelog data and manage the timelog approval process.Type: GrantFiled: June 11, 2021Date of Patent: April 25, 2023Assignee: The Board of Trustees of the California State UniversityInventor: Brianna Wagner
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Patent number: 11634706Abstract: Aspects of the present disclosure include methods of producing modified polypeptides and modified polypeptide-ribosome or polypeptide-mRNA complexes, and methods of screening polynucleotide and polypeptide libraries. The present disclosure also provides polypeptide libraries useful in screening for single molecule phenotypes. Also provided are kits useful for producing polypeptides capable of being modified using methods disclosed herein.Type: GrantFiled: September 15, 2015Date of Patent: April 25, 2023Assignee: The Trustees of the California State UniversityInventor: Kambiz Hamadani
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Patent number: 11589782Abstract: Contemplated systems for monitoring and analysis of human motion synthesis are disclosed herein that include: at least one garment configured to be worn by a user, at least one inertial sensor, wherein the at least one inertial sensor is integrated with or into the at least one garment, an information system, wherein the information system communicates with the at least one inertial sensor to produce a set of data, at least one musculorientation metric generated by the information system, and at least one performance report that is produced from the analysis of the at least one musculorientation metric.Type: GrantFiled: August 17, 2020Date of Patent: February 28, 2023Assignee: The Trustees of the California State UniversityInventors: Emel Demircan, I-Hung Khoo, Elliot Recinos
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Publication number: 20230055260Abstract: Ferromagnetic materials are disclosed that comprise at least one Dirac half metal material. In addition, Dirac half metal materials are disclosed, wherein the material comprises a plurality of massless Dirac electrons. In addition, ferromagnetic materials are disclosed that includes at least one Dirac half metal material, wherein the material comprises a plurality of massless Dirac electrons, wherein the material exhibits 100% spin polarization, and wherein the plurality of electrons exhibit ultrahigh mobility. Spintronic devices and heterostructures are also disclosed that include a Dirac half metal material.Type: ApplicationFiled: November 4, 2022Publication date: February 23, 2023Applicant: The Trustees of the California State UniversityInventors: Nicholas Kioussis, Qilong Sun
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Patent number: 11573679Abstract: Methods of real-time emoji and emoticon production are disclosed that include: determining, by a computing device, at least one first emotional state of a user from information, wherein the at least one first emotional state is a presently-identified emotional state of the user; providing an emoji or emoticon production template system, wherein the template system includes at least one physical attribute of the user; and utilizing the emoji or emoticon production template system to: analyze the presently-identified emotional state of the user; determine a suitable map of the presently-identified state of the user; map the presently-identified state of the user on an emoji or emoticon production template; produce at least one unique emoji or emoticon based on the map; provide the at least one unique emoji or emoticon to the user, wherein the user selects the at least one unique emoji or emoticon and includes the at least one unique emoji or emoticon in a text message, a direct message, an electronic mail messaType: GrantFiled: April 30, 2019Date of Patent: February 7, 2023Assignee: The Trustees of the California State UniversityInventors: Li Liu, Dragos Guta
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Patent number: 11495381Abstract: Ferromagnetic materials are disclosed that comprise at least one Dirac half metal material. In addition, Dirac half metal materials are disclosed, wherein the material comprises a plurality of massless Dirac electrons. In addition, ferromagnetic materials are disclosed that includes at least one Dirac half metal material, wherein the material comprises a plurality of massless Dirac electrons, wherein the material exhibits 100% spin polarization, and wherein the plurality of electrons exhibit ultrahigh mobility. Spintronic devices and heterostructures are also disclosed that include a Dirac half metal material.Type: GrantFiled: February 28, 2019Date of Patent: November 8, 2022Assignee: The Trustees of the California State UniversityInventors: Nicholas Kioussis, Qilong Sun
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Patent number: 11410258Abstract: The invention is directed to a system and method for collection, distribution and delivery of university student enrollment, progress, and degree completion data, media content, and other data to campus students, faculty, users, employees, and external stakeholders, and more particularly to an integrated distribution system and method that obtains data from multiple sources into a single database, extracts and validates relevant data from the multiple sources and removes legacy formatting and non-essential information, provides user-centric reports, and distributes graphic media from one or more filtered special-purpose user-centric reports that is published to user display devices.Type: GrantFiled: October 10, 2019Date of Patent: August 9, 2022Assignee: Board of Trustees, California State UniversityInventors: Jeff Gold, Desdemona Cardoza, Roy Stripling
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Patent number: 11279626Abstract: Provided is a method of extracting a metal ion, which comprises contacting a compound of formula (R2SiO)n with a source of the metal ion, whereby the compound and the metal ion form a complex, wherein each R is independently C1-10alkyl, and n is 3-10.Type: GrantFiled: June 11, 2019Date of Patent: March 22, 2022Assignee: Board of Trustees of the California State UniversityInventors: Robert E. Pellenbarg, Kimberley R. Cousins
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Publication number: 20210390154Abstract: A system, methods and software for administering and managing experiential learning opportunities (ELOs) are disclosed. The system generally includes a database server storing a relational database containing ELO placement data and records and having an interface configured to communicate with a university computer having a student information database thereon, website server, configured to host an ELO website through which users interact with the relational database, and a memory in the website server, storing a content management system (CMS) that comprises modules and a data pool stored in/on storage nodes on the website server. The modules include a forms module for users to enter ELO data and submit ELO requests, ELO proposals, waivers and agreements, and a timelog module to collect and store timelog data and manage the timelog approval process.Type: ApplicationFiled: June 11, 2021Publication date: December 16, 2021Applicant: The Board of Trustees of the California State UniversityInventor: Brianna WAGNER
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Patent number: 11149061Abstract: A method of purifying an antifreeze protein (AFP) and methods of producing AFPs are disclosed. The method of purifying an AFP includes heating a crude AFP in an aqueous medium to a temperature and for a length of time sufficient to precipitate at least some thermally unstable proteins in the crude AFP and form a precipitate and a supernatant; and removing the precipitate from the supernatant. One method of producing an AFP includes collecting a crude source of the AFP; and purifying the AFP by the purification method. Another method of producing an AFP includes growing or culturing a host configured to express a recombinant AFP in a growth medium, and collecting a crude AFP from the host and/or the growth medium. The growth medium comprises water, a protein hydrolysate or other source of amino acids, a yeast extract, a biologically metabolizable C3-C6 polyol, and one or more phosphate salts.Type: GrantFiled: December 27, 2019Date of Patent: October 19, 2021Assignees: The Board of Trustees of the California State University, California State University, Los AngelesInventor: Xin Wen
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Patent number: 11110176Abstract: Embodiments of the disclosure pertain to compositions containing (i) one or more non-antifreeze proteins or cell components or cells and (ii) one or more antifreeze proteins (AFPs), mimetics thereof, and/or analogs thereof, and a method of stabilizing a biologic (e.g., a protein, microbe, cell component or cell) against temperature stress and aggregation. The AFP may be selected from known antifreeze polypeptides and antifreeze peptides, analogs and mimetics of antifreeze proteins, active fragments of such antifreeze proteins, polypeptide and peptide mimetics, antifreeze peptoids and polymers, and combinations thereof. The non-antifreeze protein, cell component or cell comprises a known protein, cell component or cell used in the pharmaceutical, medical, agricultural, veterinary and/or food industry(ies). The AFP protects the function of the non-antifreeze protein, microbe(s), cell component(s) or cell(s) under temperature stress (e.g., a temperature of ?20-60° C.).Type: GrantFiled: November 22, 2017Date of Patent: September 7, 2021Assignee: The Board of Trustees of the California State UniversityInventor: Xin Wen
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Patent number: 10562937Abstract: Spin-labeled ice binding compounds (IBCs) including ice binding proteins (IBPs) or antifreeze proteins (AFPs) and their analogs may carry paramagnetic centers for dynamic nuclear polarization (DNP), for enhancing nuclear magnetic resonance (NMR) signal intensities. Use of spin-labeled IBCs to perform DNP exploits the IBCs' ability to homogeneously distribute the paramagnetic centers in frozen water solution at low temperature, leading to high DNP efficiency. Other advantages of using spin-labeled IBCs include cryo-protecting biological samples; cryo-preserving relative positions and orientations of the spin labeling groups; selecting positions and orientations of spin labeling groups with freedom and without technical barriers to making multiple spin labels in an IBC; and enabling use of a solvent that is primarily water for DNP at low temperatures in view of the potentially high water solubilities of spin-labeled IBCs.Type: GrantFiled: July 17, 2017Date of Patent: February 18, 2020Assignee: The Trustees of California State UniversityInventors: Yong Ba, Yougang Mao
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Patent number: 10519521Abstract: Precipitation of a carbohydrate, such as trehalose, in a solution is prevented by mixing an effective amount of at least one antifreeze protein with the carbohydrate in the solution, wherein the antifreeze protein is in whole or in part one of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, and SEQ ID NO: 4, and the antifreeze protein mass to the carbohydrate mass is between about 1:8000 and 1:30. The method is especially useful for improving the applications of a carbohydrate, such as trehalose, and the quality of the carbohydrate-containing products in industries by preventing crystallization of the carbohydrate in formulations and products.Type: GrantFiled: March 10, 2016Date of Patent: December 31, 2019Assignee: The Trustees of California State UniversityInventors: Xin Wen, Sen Wang
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Patent number: 10522169Abstract: A system is provided to determine teaching technique based upon sound amplitude comprising: processor; and a memory device holding an instruction set executable on the processor to cause the computer system to perform operations comprising: sampling amplitude of sound at a sampling rate; assigning a respective sound amplitude and a respective amplitude variation to the respective sound sample; and classifying the sound samples based upon the assigned sound amplitude and sound sample variation.Type: GrantFiled: September 8, 2017Date of Patent: December 31, 2019Assignee: TRUSTEES OF THE CALIFORNIA STATE UNIVERSITYInventors: Kimberly Tanner, Melinda T. Owens, Jeffrey Schinske, Mike Wong, Shannon Seidel
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Patent number: 10426159Abstract: New, highly efficient enhancers for AFPs have now been discovered in the form of co-enzymes, and active fragments and mimetics thereof. These enhancer molecules do not have TH activity themselves, but can enhance the TH activity of AFPs by at least about 2-11 times. These molecules are so far the most effective enhancers for AFPs, and are characterized by containing coenzymes or fragments or mimetic thereof.Type: GrantFiled: March 15, 2013Date of Patent: October 1, 2019Assignee: The Trustees of California State UniversityInventor: Xin Wen
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Patent number: 10208167Abstract: A compound comprising a cyclodextrin and a monoalkoxy polyethylene glycol linked thereto through an ether bond (a “pegylated cyclodextrin”) is disclosed, as are drug delivery vehicles and pharmaceutical formulations including the same, and methods for making the compound and the drug delivery vehicle and for delivering the drug to a patient in need thereof. The method of making includes the steps of creating either a tosylated monoalkoxy polyethylene glycol or a tosylated cyclodextrin, and either reacting the tosylated monoalkoxy polyethylene glycol with a deprotonated cyclodextrin, or reacting the tosylated cyclodextrin with a deprotonated monoalkoxy polyethylene glycol. The present pegylated cyclodextrin readily forms an inclusion compound with certain drugs to protect the drug against adverse interactions with mucin (e.g., in a mucus membrane).Type: GrantFiled: October 5, 2016Date of Patent: February 19, 2019Assignee: The Board of Trustees of the California State UniversityInventors: Yong Ba, Kim Trang Huu Nguyen