Patents Assigned to The University of Sydney
  • Patent number: 8825456
    Abstract: A method of computerized data analysis and synthesis is described. First and second datasets of a quantity of interest are stored. A Gaussian process model is generated using the first and second datasets to compute optimized kernel and noise hyperparameters. The Gaussian process model is applied using the stored first and second datasets and hyperparameters to perform Gaussian process regression to compute estimates of unknown values of the quantity of interest. The resulting computed estimates of the quantity of interest result from a non-parametric Gaussian process fusion of the first and second measurement datasets. The first and second datasets may be derived from the same or different measurement sensors. Different sensors may have different noise and/or other characteristics.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: September 2, 2014
    Assignee: The University of Sydney
    Inventors: Shrihari Vasudevan, Fabio Tozeto Ramos, Eric Nettleton, Hugh Durrant-Whyte
  • Patent number: 8796359
    Abstract: The invention provides a method of polymerizing monomer to form polymer at the surface of solid particulate material, said method comprising: providing a dispersion of said solid particulate material in a continuous hydrophilic liquid phase, said dispersion comprising a hydrophilic RAFT agent as a stabilizer for said solid particulate material, and said continuous hydrophilic liquid phase comprising one or more ethylenically unsaturated monomers; and polymerizing said one or more ethylenically unsaturated monomers under the control of said hydrophilic RAFT agent to thereby form polymer at the surface of said solid particulate material.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: August 5, 2014
    Assignee: The University of Sydney
    Inventors: Brian Stanley Hawkett, Christopher Henry Such, Duc Ngoc Nguyen
  • Patent number: 8779029
    Abstract: The invention provides a method of polymerising monomer to form polymer at the surface of solid particulate material, said method comprising: providing a dispersion of said solid particulate material in a continuous hydrophilic liquid phase, said dispersion comprising a hydrophilic RAFT agent as a stabiliser for said solid particulate material, and said continuous hydrophilic liquid phase comprising one or more ethylenically unsaturated monomers; and polymerising said one or more ethylenically unsaturated monomers under the control of said hydrophilic RAFT agent to thereby form polymer at the surface of said solid particulate material.
    Type: Grant
    Filed: April 3, 2007
    Date of Patent: July 15, 2014
    Assignee: The University of Sydney
    Inventors: Brian Stanley Hawkett, Christopher Henry Such, Duc Ngoc Nguyen
  • Publication number: 20140192952
    Abstract: A method of optimizing 4D cone beam computed tomography (4DCBCT) imaging is provided that includes using a scanner to generate projections of a target, where the projections are used to form a cone beam computed tomography (CBCT) scan of the target, where the CBCT includes a 3D image of the target, and using an appropriately programmed computer to control rotation speed of a gantry and projection acquisition of the CBCT in real-time according to a measured patient respiratory signal, where the real-time acquisition of the CBCT forms an optimized 4DCBCT image set.
    Type: Application
    Filed: July 27, 2012
    Publication date: July 10, 2014
    Applicants: The University of Sydney, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Paul J. Keall, Ricky O'Brien, Benjamin J. Cooper, Jun Lu, Jeffrey F. Williamson
  • Patent number: 8768659
    Abstract: A method for modelling a dataset includes a training phase, wherein the dataset is applied to a non-stationary Gaussian process kernel in order to optimize the values of a set of hyperparameters associated with the Gaussian process kernel, and an evaluation phase in which the dataset and Gaussian process kernel with optimized hyperparameters are used to generate model data. The evaluation phase includes a nearest neighbor selection step. The method may include generating a model at a selected resolution.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: July 1, 2014
    Assignee: The University of Sydney
    Inventors: Shrihari Vasudevan, Fabio Tozeto Ramos, Eric Nettleton, Hugh Durrant-Whyte
  • Patent number: 8765163
    Abstract: The present invention relates to a biocompatible ceramic material comprising Sr, Mg or Ba doped Hardystonite (Ca2ZnSi2O7), and a method for its synthetic preparation. The present invention also relates to an implantable medical device comprising biocompatible doped Hardystonite, and a method for its production. The present invention further relates to a method for improving the long term stability of an implantable medical device and an implantable drug delivery device comprising doped Hardystonite. Further, the present invention relates to the use of comprising biocompatible doped Hardystonite in the regeneration or resurfacing of tissue.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: July 1, 2014
    Assignee: The University of Sydney
    Inventors: Hala Zreiqat, Chengtie Wu, Colin Dunstan
  • Patent number: 8765183
    Abstract: The present invention relates to polymer microgel beads having a polymeric matrix with nanomagnetic particles dispersed substantially uniformly therethrough, wherein a steric stabiliser is associated with the particles, the steric stabiliser being a polymeric material that (i) does not form part of the polymeric matrix of the beads, and (ii) comprises a steric stabilising polymeric segment and an anchoring polymeric segment, wherein the steric stabilising polymeric segment is different from the anchoring polymeric segment, and wherein the anchoring polymeric segment has an affinity toward the surface of the nanomagnetic particles and secures the stabiliser to the particles.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: July 1, 2014
    Assignee: The University of Sydney
    Inventors: Brian Stanley Hawkett, Nirmesh Jain
  • Patent number: 8765677
    Abstract: This invention relates to an isolated, synthetic or recombinant peptide, wherein the peptide comprises the sequence: C K G K G A Xaa1 C R Xaa2 Xaa3 Xaa4 Y Xaa5 C C Xaa6 G Xaa7 C R Xaa8 Xaa9 R C SEQ ID NO: 1 wherein Xaa1, Xaa3, Xaa4, Xaa6, Xaa7 and Xaa8 are independently selected from serine and threonine; Xaa2 is selected from arginine and lysine; Xaa5 is selected from aspartic acid and glutamic acid; and Xaa9 is selected from glycine, alanine, valine, leucine and isoleucine.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: July 1, 2014
    Assignees: The University of Queensland, The University of Sydney
    Inventors: Richard Lewis, David John Adams, Geza Berecki, Roger Drinkwater, Paul Francis Alewood, MacDonald James Christie
  • Publication number: 20140126822
    Abstract: A method and apparatus for processing images, the method comprising: using a radar (4), generating a first image of an area of terrain (8); using a sensor (5), generating a second image of the area of terrain (8); performing an image segmentation process on the first image to identify a point in the first image as corresponding to a ground surface of the area of terrain (8); and projecting the identified point in the first image from the first image into the second image to identify a point in the second image as corresponding to the ground surface of the area of terrain (8). The method may further comprise: for the identified point in the second image, defining a sub-image of the second image containing that point; and performing a feature extraction process on the sub-image to identify points in the sub-image that correspond to the ground surface.
    Type: Application
    Filed: March 9, 2012
    Publication date: May 8, 2014
    Applicant: THE UNIVERSITY OF SYDNEY
    Inventors: James Patrick Underwood, Bertrand Douillard, Giulio Reina, Annalisa Milella
  • Patent number: 8718411
    Abstract: A method and apparatus for providing optical supercontinuum. The method comprises creating a spectrally narrow phase feature within a supercontinuum spectrum produced from a laser pulse that has been subjected to supercontinuum generation, thereby producing a modified supercontinuum spectrum, and propagating the modified supercontinuum spectrum through an optical waveguide that is suitable for supercontinuum generation, thereby further modifying the modified supercontinuum spectrum. The method may include modifying the modified supercontinuum spectrum by increasing its energy in a vicinity of the phase feature.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: May 6, 2014
    Assignee: The University of Sydney
    Inventors: Dane Austin, Benjamin John Eggleton, Carel Martijn De Sterke, Paul Steinvurzel, Jeremy Bolger, Thomas Brown, Feng Luan, Dong-Il Yeom
  • Publication number: 20140118150
    Abstract: A system (10) and method for use by a subject with a sleep disorder, such as nocturnal enuresis. The system (10) comprises at least one sensor (11) that detects at least one attribute of the sleep disorder, for example urine, and outputs at least a first signal on or after detection of that attribute. The system (10) further comprises a control device (12) that comprises an arousal device (14), such as a loudspeaker, that activates on or after receipt of the first signal, an interactive device (15) that is actuable by the subject to deactivate or modify the operation of the arousal device (14) and an output device (16) for delivering an output to the subject. The output being delivered on or after deactivation or modification of the arousal device (14).
    Type: Application
    Filed: January 3, 2014
    Publication date: May 1, 2014
    Applicants: The University of Sydney, The Sydney Children's Hospitals Network (Randwick and Westmead)
    Inventors: Patrina Ha Yuen Caldwell, Michael Lance Dickinson, James Charles Kerr McCauley, Geoffrey Gordon Wickham
  • Patent number: 8710015
    Abstract: The invention relates to derivatives of tropoelastin and variants of those derivatives. The invention further provides expression products and hybrid molecules of the derivatives and variants of the invention. The invention further provides methods for the production of the derivatives, variants, expression products and hybrid molecules. Further provided are formulations, cross-linked structures and implants comprising the derivatives, variants, expression products and hybrid molecules of the invention. Further provided are uses of the derivatives, variants, expression products and hybrid molecules of the invention.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: April 29, 2014
    Assignee: University of Sydney
    Inventor: Anthony S. Weiss
  • Patent number: 8709486
    Abstract: The present invention relates to a composition suitable for administration to a subject, the composition comprising pharmacologically acceptable particulate material dispersed throughout a pharmacologically acceptable liquid carrier, the particulate material being maintained in the dispersed state by a steric stabilizer, wherein the steric stabilizer is a polymeric material comprising a steric stabilizing polymeric segment and an anchoring polymeric segment, one or both of which are derived from one or more ethylenically unsaturated monomers that have been polymerized by a living polymerization technique, wherein the steric stabilizing polymeric segment is different from the anchoring polymeric segment, and wherein the anchoring polymeric segment has an affinity toward the surface of the particulate material and secures the stabilizer to the particulate material.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: April 29, 2014
    Assignee: The University of Sydney
    Inventors: Brian Stanley Hawkett, Nirmesh Jain, Thi Thuy Binh Pham, Yanjun Wang, Gregory Goodman Warr
  • Patent number: 8701498
    Abstract: A device for determining material properties includes a bottom panel extending from a first end to a second end of the device, for supporting a material to be tested. A closed loop flexible wall extends upwardly from the panel and is in operational engagement with a flexible wall idle means towards the first end of the device and a flexible wall driving means in spaced relation with the flexible wall idle means. The flexible wall driving means causes movement of the closed loop flexible wall along a predetermined closed loop path. The flexible wall driving means and the means of driving it are arranged at a position outside of a material containment area of the device.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: April 22, 2014
    Assignee: The University of Sydney
    Inventors: Itai Einav, Pierre Rognon, Thomas Miller
  • Publication number: 20140105940
    Abstract: The present invention relates to a biocompatible material and in particular to a two-phase or composite biocompatible ceramic material, wherein the first phase is a doped calcium zinc silicate and the second phase is a metal oxide. In an embodiment, the invention has been developed for use in tissue regeneration including bone tissue. In other embodiments, the invention has been developed as a coating to improve the long-term stability of prior art implantable medical devices.
    Type: Application
    Filed: June 1, 2012
    Publication date: April 17, 2014
    Applicant: The University of Sydney
    Inventors: Hala Zreiqat, Seyed-Iman Roohani-Esfahani, Colin Dunstan, Jiao Jiao Li
  • Publication number: 20140083767
    Abstract: A system and method for the drilling of ground holes by a track steer drill rig including a drilling arrangement that permits the speed of drilling holes to be balanced against the stability of the hole thus formed.
    Type: Application
    Filed: July 24, 2013
    Publication date: March 27, 2014
    Applicants: University of Sydney, Technological Resources Pty. Limited
    Inventors: Charles McHugh, Florian Andreas Oppoizer
  • Patent number: 8648727
    Abstract: A system (10) and method for use by a subject with a sleep disorder, such as nocturnal enuresis. The system (10) comprises at least one sensor (11) that detects at least one attribute of the sleep disorder, for example urine, and outputs at least a first signal on or after detection of that attribute. The system (10) further comprises a control device (12) that comprises an arousal device (14), such as a loudspeaker, that activates on or after receipt of the first signal, an interactive device (15) that is actuable by the subject to deactivate or modify the operation of the arousal device (14) and an output device (16) for delivering an output to the subject. The output being delivered on or after deactivation or modification of the arousal device (14).
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: February 11, 2014
    Assignees: The Sydney Children's Hospitals Network (Randwick and Westmead), The University of Sydney
    Inventors: Patrina Ha Yuen Caldwell, Michael Lance Dickinson, James Charles Kerr McCauley, Geoffrey Gordon Wickham
  • Patent number: 8628745
    Abstract: A process for producing ammonium nitrate is disclosed and in which: a) a gaseous oxidizer feed composed at least substantially of ammonia, steam and an oxidizing gas is exposed to conditions whereby the ammonia is oxidized to produce a reaction mixture including nitrogen monoxide and water vapor, b) the reaction mixture is cooled in a heat exchanger whereby the nitrogen monoxide is oxidized, the water vapor is condensed and the products of the nitrogen monoxide oxidation react with and are absorbed by the condensed water to form a nitric acid stream, with substantially all of the nitrogen monoxide in the reaction mixture being converted to nitric acid, and c) the nitric acid stream is reacted with a stream of ammonia in an ammonium nitrate producing stage to form the ammonium nitrate.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: January 14, 2014
    Assignees: The University of Sydney, Orica International Pte Ltd.
    Inventors: Anthony Matthew Johnston, Brian Scott Haynes
  • Patent number: 8629318
    Abstract: The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: January 14, 2014
    Assignee: University of Sydney
    Inventors: Christopher Liddle, Bryan James Goodwin, Graham Robertson
  • Patent number: 8623356
    Abstract: The present invention relates generally to a set of synthetic immunointeractive molecules referred to herein as “demibodies” which are useful in targeting particular cells in a subject. More particularly, the present invention provides a set of demibodies wherein at least two molecules from within the set, each specific for a different antigen on a target cell, are required to interact together at the cell surface in order to form an active complex which directs demibody-mediated cellular or complement mediated cytotoxicity and/or reporter function and/or therapeutic activity. The demibodies of the present invention are useful in the targeting of particular cells such as cancer cells including leukemic cells, pathogens including malarial, bacterial and viral agents, and stem cells including embryonic and adult stem cells and pathogen cells. The present invention provides, therefore, methods of treatment, diagnosis and undertaking research and compositions comprising demibodies useful for same.
    Type: Grant
    Filed: November 29, 2006
    Date of Patent: January 7, 2014
    Assignee: The University of Sydney
    Inventors: Richard Ian Christopherson, Jacqueline Mary Matthews, Joel Peter MacKay