Abstract: The invention provides a GM-CSF neutralizing human monoclonal antibody, 1783J22, as well as methods of making and use thereof. The monoclonal antibody is further characterized by its ability to bind epitopes from GM-CSF proteins of multiple species.
Type:
Grant
Filed:
April 23, 2010
Date of Patent:
December 17, 2013
Assignee:
Theraclone Sciences, Inc.
Inventors:
Po-Ying Chan-Hui, Steven Frey, Andres G. Grandea, III, Thomas C. Cox
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Type:
Grant
Filed:
August 23, 2011
Date of Patent:
June 11, 2013
Assignee:
Theraclone Sciences, Inc.
Inventors:
Andres Grandea, III, Gordon King, Thomas Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle
Abstract: The invention provides isolated fully human monoclonal anti-HRV antibodies, as well as method of making and using these antibodies. Anti-HRV antibodies of the invention prevent or treat subjects having HRV-infections, and related diseases, including, but not limited to, the common cold, nasopharyngitis, croup, pneumonia, bronchiolitis, asthma, chronic obstructive pulmonary disease (COPD), sinusitis, bacterial superinfection, and cystic fibrosis.
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Type:
Application
Filed:
March 13, 2012
Publication date:
December 13, 2012
Applicant:
Theraclone Sciences, Inc.
Inventors:
Andres G. Grandea, III, Gordon King, Thomas C. Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle, Phil Hammond
Abstract: The present invention provides novel peptide immunogens comprising influenza virus matrix 2 protein epitopes and related compositions and methods. The present invention relates to a composition comprising a peptide immunogen useful for the prevention and treatment of an influenza virus-mediated disease. The invention also relates to vaccines, immunogenic products and immunogenic compositions containing the peptide immunogens.
Abstract: The present invention provides novel anti-cytomegalovirus antibodies and related compositions and methods. These antibodies may be used in the diagnosis, prevention, and treatment of cytomegalovirus infection.
Abstract: The present invention provides novel peptide immunogens comprising influenza virus matrix 2 protein epitopes and related compositions and methods. The present invention relates to a composition comprising a peptide immunogen useful for the prevention and treatment of an influenza virus-mediated disease. The invention also relates to vaccines, immunogenic products and immunogenic compositions containing the peptide immunogens.
Abstract: The present invention provides novel anti-cytomegalovirus antibodies and related compositions and methods. These antibodies may be used in the diagnosis, prevention, and treatment of cytomegalovirus infection.
Abstract: The present invention provides compositions, vaccines, and methods for diagnosing, treating, and preventing influenza infection using a combination of antibodies raised against the influenza hemagglutinin and the matrix 2 ectodomain polypeptides.
Type:
Application
Filed:
February 14, 2012
Publication date:
August 16, 2012
Applicant:
Theraclone Sciences, Inc.
Inventors:
Andres G. Grandea, III, Gordon King, Thomas C. Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle, Phil Hammond
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Type:
Application
Filed:
August 23, 2011
Publication date:
July 5, 2012
Applicant:
Theraclone Sciences, Inc.
Inventors:
Andres Grandea, III, Gordon King, Thomas Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Type:
Application
Filed:
May 20, 2010
Publication date:
May 17, 2012
Applicant:
Theraclone Sciences, Inc.
Inventors:
Andres G. Grandea, III, Gordon King, Thomas c. Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle, Phil Hammond
Abstract: The present invention provides novel human anti-Influenza antibodies and related compositions and methods. These antibodies are used in the prevention, inhibition, neutralization, diagnosis, and treatment of influenza infection.
Type:
Application
Filed:
August 12, 2011
Publication date:
February 16, 2012
Applicant:
THERACLONE SCIENCES, INC.
Inventors:
OLE OLSEN, CHRISTINA L. BOOZER, ANDRES G. GRANDEA, III
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Type:
Grant
Filed:
March 17, 2010
Date of Patent:
February 14, 2012
Assignee:
Theraclone Sciences, Inc.
Inventors:
Andres Grandea, III, Gordon King, Thomas Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle
Abstract: The present invention provides novel anti-cytomegalovirus antibodies and related compositions and methods. These antibodies may be used in the diagnosis, prevention, and treatment of cytomegalovirus infection.
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Type:
Grant
Filed:
November 12, 2008
Date of Patent:
November 15, 2011
Assignee:
Theraclone Sciences, Inc.
Inventors:
Andres Grandea, III, Gordon King, Thomas Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle
Abstract: The present invention provides novel anti-cytomegalovirus antibodies and related compositions and methods. These antibodies may be used in the diagnosis, prevention, and treatment of cytomegalovirus infection.
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Type:
Application
Filed:
June 7, 2010
Publication date:
February 10, 2011
Applicant:
Theraclone Sciences Inc.
Inventors:
Andres G. Grandea, III, Gordon King, Thomas C. Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle, Phil Hammond
Abstract: The invention provides a GM-CSF neutralizing human monoclonal antibody, 1783J22, as well as methods of making and use thereof. The monoclonal antibody is further characterized by its ability to bind epitopes from GM-CSF proteins of multiple species.
Type:
Application
Filed:
April 23, 2010
Publication date:
November 18, 2010
Applicant:
Theraclone Sciences, Inc.
Inventors:
Po-Ying Chan-Hui, Steven Frey, Andres G. Grandea, III, Thomas C. Cox
Abstract: The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
Type:
Application
Filed:
March 17, 2010
Publication date:
July 15, 2010
Applicant:
Theraclone Sciences, Inc.
Inventors:
Andres Grandea, III, Gordon King, Thomas Cox, Ole Olsen, Jennifer Mitcham, Matthew Moyle