Abstract: The invention here provides a support, in particular a mattress or a part of a mattress, that preferably has a number of layers (11, 12) of elastic tubes (13). The tubes (13) of each layer (11 and 12) extend parallel to one another. The tubes (13) of different layers (11, 12), however, extend in a preferably crosswise manner to one another. Due to the elastic tubes (13), the inventive support or mattress provides a high degree of sitting and lying comfort with amazingly simple means.

Abstract: Adequately designed transportable data carriers are used for different applications.

Abstract: A positive displacement pump (1) for transporting a fluid with automatic adaptation to the compressibility of that fluid has a pumping chamber (15) with a variable volume (V) which is on the one hand delimited by a rigid chamber cover plate (10) and on the other hand by an elastic diaphragm (9), a suction channel (29) which is in flow connection with the pumping chamber (15) for sucking the fluid to be transported into the pumping chamber (15), an outlet channel (24) which is in flow connection with the pumping chamber (15) for discharging the fluid to be transported from the pumping chamber (15), and a drive device (29) for cyclically increasing and reducing the current volume (V) of the pumping chamber (15), with the drive device (29) being connected to the diaphragm (9) by means of a diaphragm connecting element (34; 34a; 34b) which is spring-mounted in the drive device (29) by means of a spring element (33; 33a; 33b).

Abstract: The spray can has a valve disk (12) with a valve, which valve disk is formed with a valve dome (16) and a fastening collar (18) surrounding it at a radial intermediate distance. The valve is actuated by pushing down a rotatable spray head (22) seated on a tappet (20). For obtaining turning stops for an actuating position and a closing position without taking special steps on the valve disk (12) or can body (10), it is provided that a stop ring (30) is arranged, fixed against relative rotation, in the annular space between the valve dome (16) and the collar (18). For being adaptable to materials of different thickness of the valve disk (12), it is formed with lamellas (35) at the outer circumference, is pushed with press fit into the collar (18) and has a cam track (36) with at least one recess extending along the circumference. The spray head (22) is formed or connected with at least one cam (46, 48). It acts together with turning stop faces (56) on the stop ring (30).

Abstract: The present invention relates to modified amino acids of general formula 1

Abstract: For a pressure reduction, an aerosol spray can filled with a compressed pressure gas requires, upstream of its spray valve (14), a pressure regulation valve (10) with a closing point (28). In known embodiment types a flow occurs around the outside of the pressure reduction valve, which requires a complicated housing structure. It is therefore proposed that the connection between the closing point (28) and the spray valve (14) take place via a central bore (58) in the piston (22) of the pressure reduction valve (10), preferably without a flow through the pressure chamber (26), but instead past the latter. The simple construction is advantageous, with which it is also possible to provide easy access to the piston (22) from the outside in order to maintain it in its opened position for easier filling under pressure.

Abstract: The invention is a profiled bar, in particular sprung bars, in which a reinforcement of both synthetic fibers and natural fibers is embedded in a plastic matrix. The proportion of synthetic fibers can be reduced by using natural fibers derived from regrowing raw materials. This improves environmental compatibility and makes it easier to dispose of such sprung bars. The sprung bars are used in particular to form bottom sprung supports for furniture for sitting and lying on, and in particular for slatted frames.

Abstract: The present invention relates to modified amino acids of general formula wherein A, Z, X, n, m, R, R2, R3, R4 and R11 are defined as in claims 1 to 5, their tautomers, their diastereomers, their enantiomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them as well as their use for the production and purification of antibodies and as labelled compounds in RIA- and ELISA assays and as diagnostic or analytical aids in neurotransmitter research.

Abstract: The present application relates to the uses of phenylacetic acid benzylamides and new (S)(+)-2-ethoxy-4-[N-[1-2-piperidino-phenyl)-3-methyl-1-butyl]-aminocarbon ylmethyl]-benzoic acid and the salts thereof, which have valuable pharmacological properties, namely an effect on the intermediate metabolism, but particularly the effect of lowering blood sugar.

Abstract: NPY-antagonistic compounds of the formula ##STR1## Exemplary are: (A) (R)-N-[[4-(Aminocarbonylaminomethyl)phenyl]methyl]-N.sup.2 -bis(4-hydroxyphenyl)acetyl]-argininamide-trifluoracetate;(B) (R)-N-[[4-(Aminocarbonylaminomethyl)phenyl]methyl]-N.sup.2 -[bis(4-chlorphenyl)acetyl]-argininamide-trifluoracetate;(C) (R)-N-[[4-Aminocarbonylaminomethyl)phenyl]methyl]-N.sup.2 -(diphenylacetyl)-argininamide-trifluoracetate;(D) (R)-N.sup.2 -(Diphenylacetyl)-N-[[4-(ethoxycarbonylmethylamino-carbonylaminomethyl)phe nyl]methyl]-argininamide-trifluoroacetate;(E) (R,S)-N.sup.5 -(Aminoiminomethyl)-N.sup.2 -(diphenylacetyl)-N-[(4-hy-droxyphenyl)methyl]-N.sup.5 -methyl-ornithinamide-hydrochloride;(F) (R)-N-[[4-(Aminocarbonylmethyl)phenyl]methyl]-N.sup.2 -(diphenyl-acetyl)-argininamide-diacetate;(G) (R)-N.sup.2 -(Diphenylacetyl)-N-[[4-(ethylaminocarbonylamino-methyl)-phenyl]methyl]-ar gininamide-bis-(trifluoroacetate); and,(H) (R)-N.sup.

Abstract: The invention relates to a sampling device, in which the site of separation from the microbiologically contaminated environment is constructed as a sterile protective gas current according to the laminar air-flow principle under a housing bell (7), the site of connection of the inner tube (11) to the sample tube (10) being so designed that it occurs inside to just below the housing bell (7), fixedly or with no fixed connection, and for automatic operation occurs just below the housing bell (7), with no fixed connection.

Abstract: The invention relates to a strong homologous promoter from hamsters. In particular, it relates to the promoter of a gene which codes for the Ubiquitin-S27a-fusion protein. The promoter can be used in processes for preparing heterologous gene products in culture cells, particularly CHO cells.

Abstract: The invention relates to new amino acid derivatives of general formula ##STR1## wherein R, U, V, Y, n, m and R.sup.1 to R.sup.3 are defined as in claim 1, their tautomers, diastereomers, enantiomers, mixtures thereof and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable pharmacological properties, particularly selective NPY-antagonistic properties, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them.

Abstract: The specification describes a pharmaceutical combination consisting of dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing this pharmaceutical combination and the use thereof for the controlled prevention of clot formation.

Abstract: Pyrimido[5,4-d]pyrimidines of the general formula ##STR1## which have an inhibitory effect on signal transduction mediated by tyrosine kinases, their use for the treatment of oncoses, and their preparation. Exemplary compounds are:(a) 4-(5-indolylamino)-6-morpholinopyrimido[5,4-d]pyrimidine;(b) 4-(5-indolylamino)-6-[trans-(4-hydroxycyclohexyl)amino]pyrimido[5,4-d]pyri midine;(c) 4-[(3-chloro-4-fluorophenyl)amino]-6-[4-(morpholinocarbonylmethyl)-1-piper azinyl]pyrimido[5,4-d]pyrimidine;(d) 4-[(3-chloro-4-fluorophenyl)amino]-6-[(4-morpholinyl)amino]pyrimido[5,4-d] pyrimidine;(e) 4-[(3-chloro-4-fluorophenyl)amino]-6-(4-picolylamino)pyrimido[5,4-d]pyrimi dine;(f) 4-[(3-chloro-4-fluorophenyl)amino]-6-[1-trifluoroacetyl-4-piperidinylamino ]pyrimido[5,4-d]pyrimidine;(g) 4-[(3-chloro-4-fluorophenyl)amino]-6-(endo-tropinylamino)pyrimido[5,4-d]py rimidine; and,(h) 4-[(3-chloro-4-fluorophenyl)amino]-6-(exo-tropinylamino)pyrimido[5,4-d]pyr imidine.

Abstract: Compounds that inhibit the enzyme 2,3-epoxysqualene-lanosterol-cyclase and cholesterol biosynthesis, of the formula I ##STR1## wherein n denotes the number 0 or 1, m denotes the number 1 or 2, p denotes the number 0 or 1, R.sup.1 and R.sup.2 each denote hydrogen, lower alkyl, alkenyl or alkynyl, which may optionally also be substituted, or together with the nitrogen atom between the denote 5- to 7-membered saturated, monocyclic or heterocyclic rings which may optionally also be interrupted by an oxygen or sulfur atom or by an imino group, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 denote hydrogen or lower alkyl, R.sup.5 additionally denotes lower alkoxy, R.sup.7 denotes hydrogen, cycloalkyl, phenyl or substituted phenyl, naphthyl, tetrahydronaphthyl, thienyl, furyl or pyridyl and A denotes a chemical bond or alkyl, alkenyl having up to 17 carbon atoms.

Abstract: The invention relates to new amino acid derivatives of general formula ##STR1## wherein R, U, V, Y, n, m and R.sup.1 to R.sup.3 are defined as in claim 1, their tautomers, diastereomers, enantiomers, mixtures thereof and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable pharmacological properties, particularly selective NPY-antagonistic properties, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them.

Abstract: The present invention relates to phenyl amidines of general formula (I), ##STR1## in which R.sup.1 to R.sup.5 are as defined in claim 1, their tautomers, their stereoisomers and their mixtures and their salts, especially their physiologically acceptable salts with inorganic or organic acids or bases also having valuable pharmacological properties, preferably aggregation-limiting effects, producing them.

Abstract: The present invention relates to piperazine derivatives of the general formula ##STR1## in which R.sub.a, Y.sub.1 to Y.sub.3 and E are defined herein, tautomers thereof, stereoisomers thereof, including their mixtures, and salts thereof, and in particular physiologically tolerated salts thereof with inorganic or organic acids or bases. These compounds have valuable pharmacological properties, such as aggregation-inhibiting activity. This invention also relates to medicaments comprising these compounds and to processes for the preparation of these compounds.

Abstract: The invention relates to biphenyl derivatives of general formula ##STR1## wherein A to E and X are defined as in claim 1, the stereoisomers thereof, including their mixtures and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties, preferably aggregation-inhibiting effects, pharmaceutical compositions containing these compounds and processes for preparing them.