Patents Assigned to Tokyo University of Science
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Publication number: 20120097205Abstract: Provided is a magnesium-silicon composite material which contains Mg2Si as an intermetallic compound imposing no burden on the environment, is suitable for use as a material for thermoelectric conversion modules, and has excellent thermoelectric conversion performance. The magnesium-silicon composite material has a dimensionless figure-of-merit parameter at 866K of 0.665 or larger. This magnesium-silicon composite material can have high thermoelectric conversion performance when used in, for example, a thermoelectric conversion module.Type: ApplicationFiled: June 30, 2010Publication date: April 26, 2012Applicant: Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Tsutomu Iida, Yasuhiko Honda, Naoki Fukushima, Tatsuya Sakamoto, Yohiko Mito, Hirokuni Nanba, Yutaka Taguchi
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Patent number: 8148058Abstract: An allergic disease-related substance is screened from candidate substances based on the reactivity to a plurality of cell lines, which are basophil-like or mast cell-like cell lines derived from the same spleen tissue and have different sensitivities to allergic cytokines. Further, an allergic disease-related substance is screened from candidate substances using at least one basophil-like or mast cell-like cell lines selected from the group consisting of R cell (Deposit No. FERM BP-10918), N 62.5 cell (Deposit No. FERM BP-10919) and RCCM cell (Deposit No. FERM BP-10920).Type: GrantFiled: November 14, 2007Date of Patent: April 3, 2012Assignee: Tokyo University of Science Educational Foundation Administrative OrganizationInventor: Ryo Abe
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Publication number: 20120074361Abstract: Copper(II) acetate, zinc(II) acetate, and tin(IV) acetate are weighed so that the total amount of metal ions is 2.0×10?4 mol and the molar ratio of ions is Cu:Zn:Sn=2:1:1, and 2.0 cm3 of oleylamine is added to prepare a mixed solution. Apart from this, 1.0 cm3 of oleylamine is added to 2.0×10?4 mol of sulfur powder to prepare a mixed solution. These mixed solutions are separately heated at 60° C. and mixed at room temperature. The pressure in a test tube is reduced, followed by nitrogen filling. The test tube is heated at 240° C. for 30 minutes and then allowed to stand until room temperature. The resultant product is separated into a supernatant and precipitates by centrifugal separation. The separated supernatant is filtered, methanol is added to produce precipitates. The precipitates are dissolved by adding chloroform to prepare a semiconductor nanoparticle solution.Type: ApplicationFiled: February 25, 2010Publication date: March 29, 2012Applicants: National University Corporation Nagoya University, Tokyo University of Science Educational Foundation Administrative Organization, Osaka UniversityInventors: Tsukasa Torimoto, Ken-ichi Okazaki, Tatsuya Kameyama, Takaaki Osaki, Susumu Kuwabata, Akihiko Kudo
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Patent number: 8115008Abstract: Disclosed is a method for producing an optically active ester by highly selectively esterifying one enantiomer of a racemic carboxylic acid, while producing an optically active carboxylic acid which is the other enantiomer. An optically active ester is produced while producing an optically active carboxylic acid at the same time by reacting a racemic carboxylic acid with a specific alcohol or phenol derivative in the presence of benzoic anhydride or a derivative thereof and a catalyst such as tetramisole or benzotetramisole, thereby selectively esterifying one enantiomer of the racemic carboxylic acid.Type: GrantFiled: March 4, 2009Date of Patent: February 14, 2012Assignee: Tokyo University of Science Education Foundation Administrative OrganizationInventors: Isamu Shiina, Kenya Nakata
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Publication number: 20120015256Abstract: Disclosed is a sodium-ion secondary battery having excellent charge and discharge efficiencies as well as excellent charge and discharge characteristics, wherein charging and discharging can be repeated without causing problems such as deterioration in battery performance. Specifically disclosed is a sodium ion secondary battery which is provided with a positive electrode, a negative electrode having a negative electrode active material, and a nonaqueous electrolyte solution containing a nonaqueous solvent. The nonaqueous solvent is substantially composed of a saturated cyclic carbonate (excluding the use of ethylene carbonate by itself), or a mixed solvent of a saturated cyclic carbonate and a chain carbonate, and a hard carbon is used as the negative electrode active material.Type: ApplicationFiled: March 25, 2010Publication date: January 19, 2012Applicant: Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Shinichi Komaba, Tomoaki Ozeki, Wataru Murata, Toru Ishikawa
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Patent number: 8093018Abstract: The present invention relates to an antibody that recognizes a first antibody, the antibody specifically recognizing one of a free first antibody and an antigen-binding first antibody. More specifically, the above antibody is a domino antibody that specifically recognizes and binds to an antigen-binding first antibody, or an antibody-unlocking antibody that specifically recognizes and binds to a free first antibody.Type: GrantFiled: May 18, 2009Date of Patent: January 10, 2012Assignees: Otsuka Pharmaceutical Co., Ltd., Tokyo University of ScienceInventors: Takachika Azuma, Hisao Takizawa
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Publication number: 20120000500Abstract: Provided is a thermoelectric conversion element which enables improvement in yield and durability, is easy to secure a temperature difference between the both ends and is easy to be bonded to an electrode without tilting, resulting in improvement of mass productivity. Also provided is a thermoelectric conversion module using the thermoelectric conversion element. A thermoelectric conversion element includes: a plurality of pole-shaped parts with one ends of which being electrically connected to a first electrode, and the pole-shaped-parts being arranged at an interval from each other; and a joining/connecting part joining/connecting the other ends of the pole-shaped parts together, and electrically connected to a second electrode. A connecting face of the joining/connecting part, the face being connected to the second electrode, is larger than the sum total of areas of one ends of the pole-shaped parts.Type: ApplicationFiled: February 24, 2010Publication date: January 5, 2012Applicant: Tokyo University of Science Education Foundation Administration OrganizationInventors: Tsutomu Iida, Yohei Oguni, Takashi Nemoto, Junichi Sato
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Publication number: 20110319650Abstract: Disclosed is a method for producing an optically active 2-hydroxy ester, comprising selectively esterifying one enantiomer of a racemic 2-hydroxy ester in a solvent containing a catalyst such as tetramisole or benzotetramisole, and a carboxylic acid anhydride, or a carboxylic acid anhydride and a carboxylic acid. In particular, in the case where the solvent contains a carboxylic acid anhydride, but does not contain a carboxylic acid, as the carboxylic acid anhydride, a carboxylic acid anhydride containing a tertiary or quaternary carbon atom in the a-position is used. On the other hand, in the case where the solvent contains a carboxylic acid anhydride and a carboxylic acid, as the carboxylic acid, a carboxylic acid containing a tertiary or quaternary carbon atom in the a-position is used.Type: ApplicationFiled: March 8, 2010Publication date: December 29, 2011Applicant: Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Isamu Shiina, Kenya Nakata
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Patent number: 8061414Abstract: A boil cooling method forms, with a surface of an object to be cooled or a surface of a heating member in close contact with the surface of the object to be cooled made to serve as a cooling surface, a main flow channel and a sub-flow channel for a cooling liquid from the side of the cooling surface in the above-described order, arranges a plurality of nozzles penetrating a partition wall separating the sub-flow channel and the main flow channel and protruding into the main flow channel in a flow channel direction of the main flow channel, causes tip end parts of individual nozzles to be in the vicinity of or in contact with the cooling surface, causes a cooling liquid to circulate to the main flow channel and the sub-flow channel, and cools the cooling surface by boiling of the cooling liquid flowing through the main flow channel, and at the same time, supplies the cooling liquid from the side of the sub-flow channel through each of the nozzles to the vicinity of the cooling surface, and cools the cooling liType: GrantFiled: December 21, 2005Date of Patent: November 22, 2011Assignee: Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Koichi Suzuki, Hiroshi Kawamura, Haruhiko Ohta, Yoshiyuki Abe
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Patent number: 8034947Abstract: The invention relates to a pyridine oxide compound represented by formula (I), an optically active compound thereof, a salt thereof and a hydrate thereof, and, in the presence of the compound as a catalyst, performing 1) a method for producing an ester compound or an amide compound from a carboxylic acid equivalent and an alcohol or an amine, 2) an asymmetric esterification reaction or 3) an asymmetric amidation reaction.Type: GrantFiled: February 17, 2006Date of Patent: October 11, 2011Assignee: Tokyo University of Science Educational Foundation Administrative OrganizationInventor: Isamu Shiina
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Patent number: 8034824Abstract: The present invention is to provide means to treat breast cancer and/or mastitis by topically administering a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent and allowing them efficiently to arrive into the mammary gland. The present invention provides an iontophoretic preparation for treating breast cancer and/or mastitis which contains a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent as an active ingredient and has a donor to be applied on a nipple part for topical administration of the active ingredient from the nipple part to the mammary gland by application of electric potential.Type: GrantFiled: October 11, 2006Date of Patent: October 11, 2011Assignees: Kowa Co., Ltd., Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Toshio Inagi, Makoto Kanebako, Hiroshi Terada, Kimiko Makino, Masakazu Toi
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Publication number: 20110135214Abstract: A simple and practical image restoring device capable of improving the performance of image restoration. An image restoring device (100) is provided with a first restoration processing unit (160a) and estimates original image information from the degraded image information into which information unnecessary for the original image information is incorporated. A correlation calculating section (164) calculates the correlation value of the estimation error of when the state amount of a system at time n+1 including the original image information is estimated by information up to time n or the time n+1 with respect to the degraded image information of only the time n.Type: ApplicationFiled: August 6, 2009Publication date: June 9, 2011Applicant: Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Nari Tanabe, Toshihiro Furukawa, Shunichi Kitahara
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Patent number: 7931821Abstract: An oxynitride piezoelectric material, which exhibits ferroelectricity and has good piezoelectric properties, and a method of producing the oxynitride piezoelectric material. The oxynitride piezoelectric material includes a tetragonal perovskite-type oxynitride represented by the following general formula (1): A1?xBix+?1B1?yB?y+?2O3?zNz??(1), where A represents a divalent element, B and B? each represent a tetravalent element, x represents a numerical value of 0.35 or more to 0.6 or less, y represents a numerical value of 0.35 or more to 0.6 or less, z represents a numerical value of 0.35 or more to 0.6 or less, and ?1 and ?2 each represent a numerical value of ?0.2 or more to 0.2 or less, in which the A includes at least one kind selected from Ba, Sr, and Ca and the B and the B? each include at least one kind selected from Ti, Zr, Hf, Si, Ge, and Sn.Type: GrantFiled: December 16, 2009Date of Patent: April 26, 2011Assignees: Canon Kabushiki Kaisha, Kyoto University, Tokyo Institute of Technology, University of Yamanashi, National Institute of Advanced Industrial Science and Technology, Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Hiroshi Saito, Takanori Matsuda, Kaoru Miura, Kenji Takashima, Masaki Azuma, Takashi Iijima, Hiroshi Funakubo, Soichiro Okamura, Nobuhiro Kumada, Satoshi Wada
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Patent number: 7906889Abstract: Provided are a piezoelectric material without using lead or an alkali metal, the piezoelectric material having a stable crystal structure in a wide temperature range, high insulation property, and high piezoelectric property, and a piezoelectric element using the piezoelectric material, in which the piezoelectric material is made of a metal oxide having a tetragonal crystal structure and expressed by Ba(SixGeyTiz)O3 (here, 0?x?1, 0?y?1, and 0?z?0.5), the piezoelectric element includes the piezoelectric material and a pair of electrodes sandwiching the piezoelectric material, and at least one of the pair of electrodes is made of SrRuO3 or Ni.Type: GrantFiled: May 22, 2009Date of Patent: March 15, 2011Assignees: Canon Kabushiki Kaisha, Tokyo Institute of Technology, Kyoto University, University of Yamanashi, National Institute of Advanced Industrial Science and Technology, Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Tatsuo Furuta, Kaoru Miura, Kenichi Takeda, Makoto Kubota, Hiroshi Funakubo, Masaki Azuma, Nobuhiro Kumada, Satoshi Wada, Takashi Iijima, Soichiro Okamura
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Publication number: 20110012050Abstract: Provided is a piezoelectric material including a lead-free perovskite-type composite oxide which is excellent in piezoelectric characteristics and temperature characteristics and is represented by the general formula (1): xABO3-yA?BO3-zA?B?O3 in which A is a Bi element; A? is a rare earth element including La; B is at least one element selected from Ti, Zn, Sn and Zr; A? is at least one element selected from Ba, Sr and Ca; B? is at least one element selected from divalent, trivalent, pentavalent, tetravalent, and hexavalent elements; and x is a value of 0.10 or more and 0.95 or less, y is a value of 0 or more and 0.5 or less, and z is a value of 0 or more and 0.7 or less, provided that x+y+z=1.Type: ApplicationFiled: March 18, 2009Publication date: January 20, 2011Applicants: UNIVERSITY OF YAMANASHI, KYOTO UNIVERSITY, TOKYO INSTITUTE OF TECHNOLOGY, CANON KABUSHIKI KAISHA, Tokyo University of Science Educational Foundation Administrative Organization, National Institute of Advanced Industrial Science and TechnologyInventors: Jumpei Hayashi, Zuyi Zhang, Toshihiro Ifuku, Satoshi Wada, Keisuke Yamato, Nobuhiro Kumada, Masaki Azuma, Hiroshi Funakubo, Takashi Iijima, Soichiro Okamura
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Publication number: 20100308204Abstract: The invention provides is a process for producing a structure (22) with a metal film, including the steps of preparing a mother die (10) in which a first metal film (16) is formed on the surface of a base (12) on which a concave and convex pattern (14) is formed, forming a second metal film (18) on the first metal film (16), adhering a support member (20) to the second metal film (18), and separating the second metal film (18) to which the concave and convex pattern has been transferred to the second metal film (18) together with the support member from the first metal film (16). Preferably, the first metal film (16) is a film containing Cr and Al, and the second metal film (18) is a film containing at least one metal selected from the group consisting of Au, Ag, Cu, Al, and Pt.Type: ApplicationFiled: February 9, 2009Publication date: December 9, 2010Applicant: Tokyo University of Science Educational Foundation Administrative OrganizationInventor: Jun Taniguchi
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Publication number: 20100262425Abstract: Disclosed is a noise suppression device capable of better noise suppression by means of a simpler structure and with a lighter computational load. A noise suppression device (100) has a noise suppression processor (150) to estimate the required information only from the observed information, which is the required information corrupted by noise. A correlator (154) calculates the correlation of the estimation error when the state quantity, which contains the required information, of the system at time n+1 was estimated from the information until time n or time n+1 for the observed information at only time n.Type: ApplicationFiled: March 18, 2009Publication date: October 14, 2010Applicant: Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Nari Tanabe, Toshihiro Furukawa
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Publication number: 20100249400Abstract: Disclosed is a compound represented by the formula (I) below as a dihydronaphthalene compound having a chemical structure which is excellent in production efficiency when compared with lasofoxifene and nafoxidine. This compound is useful as a proteasome inhibitor and/or an antitumor agent.Type: ApplicationFiled: September 11, 2008Publication date: September 30, 2010Applicant: Tokyo University of Science Educational Foundation Administrative OrganizationInventor: Isamu Shiina
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Patent number: 7723569Abstract: A plant which expresses a large amount of ubiquinone-10 and a method for producing ubiquinone-10 using the plant are provided. A dietary supplement, a food and a food additive which contains ubiquinone-10 produced by the plant or the method are provided. The plant is produced by transformation using an expression cassette in which a decaprenyl diphosphate synthase gene is operatively linked with a mitochondrial targeting sequence.Type: GrantFiled: April 29, 2005Date of Patent: May 25, 2010Assignees: National Institute of Agrobiological Sciences, National University Corporation Shimane University, Tokyo University of ScienceInventors: Koichi Kadowaki, Sakiko Takahashi, Makoto Kawamukai, Hiroaki Shimada
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Publication number: 20100025617Abstract: Provided is a piezoelectric material excellent in piezoelectricity. The piezoelectric material includes a perovskite-type complex oxide represented by the following General Formula (1). A (ZnxTi1-x))yM(1-y)O3??(1) wherein A represents at least one kind of element containing at least a Bi element and selected from a trivalent metal element; M represents at least one kind of element of Fe, Al, Sc, Mn, Y, Ga, and Yb; x represents a numerical value satisfying 0.4?x?0.6; and y represents a numerical value satisfying 0.1?y?0.9.Type: ApplicationFiled: July 24, 2009Publication date: February 4, 2010Applicants: CANON KABUSHIKI KAISHA, KYOTO UNIVERSITY, TOKYO INSTITUTE OF TECHNOLOGY, SOPHIA UNIVERSITY, UNIVERSITY OF YAMANASHI, National Institute of Advanced Industrial Sciences and Technology, Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Makoto Kubota, Kaoru Miura, Toshihiro Ifuku, Jumpei Hayashi, Masaki Azuma, Olga Alexandrovna Smirnova, Hiroshi Funakubo, Hiroshi Uchida, Nobuhiro Kumada, Satoshi Wada, Takashi Iijima, Soichiro Okamura