Abstract: A closure system includes a connector and a protective cap in which there is a liquid antiseptic. As the cap and connector are joined together, multiple seals are formed to trap the liquid antiseptic within the cap and force the antiseptic into the bore of the connector.

Abstract: A sterile, closed drug delivery system (10) is provided comprising a flexible container (12), a capsule (22) coupled to the flexible container and a standard glass drug vial (36) positioned within the capsule. The flexible container has a liquid diluent therein. The capsule has supporting legs (32-35) which extend inwardly from the capsule to support the vial and also a highly flexible, pleated cap (28) which enables the drug vial to be manually moved relative to the supporting legs. The capsule is coupled to the flexible container by means of a hollow spike (54) located within the capsule and a frangible member (58) located within the flexible container, which frangible member allows fluid passage only when it is broken. Manual pressing of the pleated cap moves the drug vial downwardly onto the spike, piercing the stopper of the drug vial. Once the frangible member is broken, there is sterile communication between the drug vial and the liquid diluent contents of the flexible container.

Abstract: A spike connector (10) of the type in which a hollowed spike (14) extending from the main body portion (12) of the spike connector is inserted into the stopper of a fluid source in order to convey the fluid from the source through the spike (14) and main body portion (12). The main body portion (12) includes a pair of wings (32, 34) which extend upwardly in the direction of the spike and outwardly therefrom, with the tops of the wings serving to space the remaining top of the main body portion (12) away from the fluid source stopper to prevent collection of the solution on the top of the main body portion. The undersides (36, 38) of the wings (32, 34) form a convenient finger grip. The tip portion (30) of the spike is relatively polished to enable easy insertion of the spike into the stopper.

Abstract: A solution bag formed of three plastic walls sealed together about their peripheries to define a pair of separate chambers is provided for peritoneal dialysis and the like.