Patents Assigned to Troikaa Pharmaceuticals Ltd.
  • Patent number: 9616128
    Abstract: Disclosed herein are injectable compositions containing high concentration of paracetamol or its pharmaceutically acceptable salts wherein the concentration of paracetamol or its pharmaceutically acceptable salt is >150 mg/ml in a judiciously tailored solvent system comprising glycofurol, ethanol, water or a solvent system comprising glycofurol, ethanol, polyethylene glycol, water. The viscosity of the said injectables is <28 cps. Further disclosed is the process for preparing the said injectables. The injectables can be administered by intramuscular route, intravenous route or as intravenous infusion after diluting in one of the routinely used intravenous fluids, infusion solutions of antibacterial, antifungal and amoebicidal drugs and along with anxiolytics (Midazolam injection) or narcotic analgesics (Fentanyl Citrate injection etc) as they remain stable, clear and transparent at least for 6 hours after dilution.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: April 11, 2017
    Assignee: Troikaa Pharmaceuticals Ltd
    Inventors: Ketan R. Patel, Milan R. Patel, Prakashchandra J. Shah
  • Patent number: 8809393
    Abstract: The present invention provides injectable formulations of water-soluble salts of diclofenac in single doses of less than 2 ml, which cause significantly less pain at the site of injection and can be administered by intradeltoid route, in addition to intragluteal and slow intravenous route. More specifically the injectable preparations contain 75 mg to 100 mg of water-soluble salts of diclofenac, in about 1 ml injection solution without significantly raising the viscosity of the injection solution without the use surfactants. The formulations are adjusted to pH 6 to 10 containing up to 100 mg of diclofenac salt in a medium comprising of water, along with one or more co-solvent(s)/solubilizer(s), antioxidants, preservatives, buffers, alkali and stabilizers.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: August 19, 2014
    Assignee: Troikaa Pharmaceuticals Ltd
    Inventors: Ketan Rajnibhai Patel, Milan Rajnibhai Patel
  • Publication number: 20080153914
    Abstract: The present invention provides injectable formulations of water-soluble salts of diclofenac in single doses of less than 2 ml, which cause significantly less pain at the site of injection and can be administered by intradeltoid route, in addition to intragluteal and slow intravenous route. More specifically the injectable preparations contain 75 mg to 100 mg of water-soluble salts of diclofenac, in about 1 ml injection solution without significantly raising the viscosity of the injection solution without the use surfactants. The formulations are adjusted to pH 6 to 10 containing up to 100 mg of diclofenac salt in a medium comprising of water, along with one or more co-solvent(s)/solubiliser(s), antioxidants, preservatives, buffers, alkali and stabilizers.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 26, 2008
    Applicant: Troikaa Pharmaceuticals Ltd.
    Inventors: Ketan Rajnibhai Patel, Milan Rajnibhai Patel