Patents Assigned to Univeristy of Pittsburgh of the Commonwealth System of Highter Education
  • Publication number: 20120330437
    Abstract: A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. 5 Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
    Type: Application
    Filed: October 28, 2010
    Publication date: December 27, 2012
    Applicant: Univeristy of Pittsburgh of the Commonwealth System of Highter Education
    Inventors: Mohammed El-Kurdi, J. Christopher Flaherty, Yi Hong, Jonathan McGrath, Lorenzo Soletti, John Stankus, David Vorp, William Wagner