Abstract: A thin packaging film 1 includes a reference area 2 having a closed contour and which is surrounded over its entire periphery by a tear-off area, an incipient tear 3 being precut in this film so as to intercept this contour while leading into the latter while forming a gripping portion 4 capable of being pulled away from the plane of this thin film, the reference area being designed so as to trap one end of this incipient tear within the contour while the other end propagates by tearing in a spiral from the tear-off area over at least 180° around this reference area when the gripping portion begins to undergo pulling. This closed contour is preferably circular. The closed contour area can in particular be an opening, or a portion of film surrounded by a reinforcement material loop.
Type:
Application
Filed:
December 2, 2010
Publication date:
September 20, 2012
Applicants:
UNIVERSIDAD DE CHILE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSIDAD DE SANTIAGO DE CHILE
Inventors:
Enrique Cerda Villablanca, Eugenio Hamm Hahn, Victor Romero Gramegna, Benoit Roman
Abstract: Method for the prevention of the tau protein aggregation and treating Alzheimer's disease by administering a quinoline derivative compound of formula wherein R2 is 2-(4-aminophenyl) or 2-(4-methylphenyl) and R6 is methyl as an inhibitor of the tau protein aggregation.
Type:
Grant
Filed:
April 29, 2010
Date of Patent:
June 12, 2012
Assignee:
Universidad De Chile
Inventors:
Ricardo B. Maccioni, Leonardo P Navarrete, Aurelio San Martin
Abstract: The present invention consists of the discovery about an ammoniacal solution of sodium azide (NaN3) or other azide salts that in low concentrations induces the budding of grapevine buds and potentially other deciduous fruit trees with the same efficiency as H2CN2 makes.
Type:
Grant
Filed:
December 6, 2006
Date of Patent:
May 8, 2012
Assignee:
Universidad De Chile
Inventors:
Francisco Javier Perez Correa, Juan Ormeno Nunez
Abstract: A biosorbent for removing cationic and/or anionic metals from aqueous solutions, and a process for the production of the biosorbent. The biosorbent includes bacterial aggregates of Bacillus sp. VCHB-10, deposited as NRRL-B-30881, and treated with polyethyleneimine and glutaraldehyde. Among the metals in their cationic form, the following are considered: cations of Ag, Al, Au, Co, Cd, Cu, Cr, Fe, Hg, Mn, Ni, Pb, Pd, Pt, U, Th and Zn. Among the metals in their anionic form, the following are considered: anions of As, Cr and Mo. Removal or recovery of metals from wastewater using the biosorbent is also described.
Type:
Application
Filed:
May 11, 2011
Publication date:
February 2, 2012
Applicants:
BIOTECNOLOGIA DEL AGUA LTDA., UNIVERSIDAD DE CHILE
Inventors:
Davor Cotoras Tadic, Pabla Viedma, Juan Manuel Gajardo Sandoval
Abstract: A large-scale attendance, productivity, activity and availability biometric control method using the telephone network, for individual client users with speaker verification technology based on limited enrolling data and short verification sentences.
Abstract: Hybrid clays for obtaining nanocomposites useful in the automotive, aviation, construction and packaging industry, among others. The hybrid clay comprises clays intercalated with the itaconic acid (ITA) monomer or its derivative monooctadecyl itaconate (MODIT), and a process for the preparation of these hybrid clays and the process to obtain polyolefin/clay nanocomposites.
Abstract: The present invention is directed to an active agent with contraceptive properties. Said active agent corresponds to a molecular fraction of the venom from the spider Latrodectus mirabilis. The active agent is a peptide with a sequence according to SEQ ID NO 1 or sequences that are at least 85% similar, obtained by chemical synthesis or through recombinant DNA technologies. In a preferred embodiment, the active agent with contraceptive properties is a peptide with 10 to 30 amino acids, preferably 20 amino acids. Said embodiment is exemplified by the sequence identified as SEQ ID NO 2 or sequences that are at least 85% similar, obtained by chemical synthesis or through recombinant DNA technologies. Furthermore, a method to obtain the contraceptive peptide is disclosed, said method comprising cloning the nucleotide sequence in a microorganism.
Type:
Application
Filed:
March 22, 2011
Publication date:
September 29, 2011
Applicants:
Universidad de la Frontera, Universidad de Chile, Universidad Federal de Sao Paulo, Laboratorios Andromaco S.A.
Inventors:
Fernando Romero Mejia, Raúl Sanchez Gutierrez, Eduardo Bustos Obregón, Antonio De Miranda, Andrés Rudolphy Fontaine
Abstract: A method of increasing the production of extracellular polymeric substances (EPS) in an Acidithiobacillus ferrooxidans culture is disclosed. The method includes inhibiting an enzyme, such as citrate synthase, aconitase, or isocitrate dehydrogenase, in the tricarboxylic acid (TCA) cycle leading to alpha-ketoglutarate.
Type:
Application
Filed:
February 25, 2011
Publication date:
September 1, 2011
Applicants:
UNIVERSIDAD DE CHILE, BIOSIGMA S.A.
Inventors:
Alejandro Eduardo Maass Sepúlveda, Pablo Andrés Moreno Cortéz, Marko Antonio Budinich Abarca, Pilar Angélica Parada Valdecantos, Leandro Mauricio Padilla Iglesias, Marlen Nayibe Barreto Roa
Abstract: Cellular migration is a normal part of the normal development of the human being and, in certain pathologies, its alteration damages physiological performance, so that it is necessary to learn about its molecular and cellular foundations and establish methodologies to identify those molecules that modulate this cellular behavior. A screening method using zebra fish embryos is used to follow the advance in the migration of the lateral line primordium upon contact with a test compound. Modulators N found are Fenritinide, PGD2 and is-deoxy-PJE2. The invention refers to a biological method for the IN VIVO, fast, massive and simultaneous tracking of molecules capable of affecting cellular migration, in order to facilitate the for of potential candidates to be used in the diagnosis, prevention, and, principally, for the preparation of pharmaceutical compositions for the treatment of congenital pathologies, immune system dysfunctions, tissue regeneration failure, inflammation, cancer.
Abstract: This invention is referred to a new bacterial strain of Bacillus sp., to be applied in a metal biosorption process, which was deposited in the Agricultural Research Culture Collection (NRRL) International Depositary Authority, 1815 N. University Street, Peoria Ill. 61604, USA, having an accession number NRRL-B-30881. It is described, also, a sporulated and non-sporulated industrial inoculant of said bacterium, a method to produce said inoculant, and a process to remove metals by said bacterium.
Type:
Grant
Filed:
June 26, 2007
Date of Patent:
May 31, 2011
Assignees:
Universidad de Chile, Biotechnologies del Agua Ltda.
Abstract: The present invention relates to an ex vivo, fast and efficient process to obtain activated antigen-presenting cells that are useful for therapies against cancer and immune system-related diseases. At the same time, it is related to a cellular composition that contributes to stimulate the activated antigen-presenting cells to induce a specific immune response against tumors in patients with cancer or other pathologies involving immune responses.
Abstract: The present invention consists of the discovery about an ammoniacal solution of sodium azide (NaN3) or other azide salts that in low concentrations induces the budding of grapevine buds and potentially other deciduous fruit trees with the same efficiency as H2CN2 makes.
Type:
Application
Filed:
December 6, 2006
Publication date:
December 31, 2009
Applicant:
UNIVERSIDAD DE CHILE
Inventors:
Francisco Javier Perez Correa, Juan Ormero Nunez
Abstract: A method and a plant to remove metals by biosorption from mining or industrial effluents comprising: (a) subject the effluent to at least one first stage of pre-treatment, selecting among: precipitation by pH rising, solvent extraction or solvent extraction on emulsified membranes in order to reduce its load of metals to a concentration level that allows it to be treated by the next stage of biosorption, and (b) subject the liquid that has been previously in the stage of pre-treatment to a second stage of continuous metals removal by biosorption.
Type:
Grant
Filed:
December 4, 2007
Date of Patent:
January 20, 2009
Assignees:
Universidad De Chile, Biotechnologies Del Aqua Ltda.
Inventors:
Davor Cotoras Tadic, Fernando Valenzuela Lozano, Miguel Esteban Zarzar Maza, Pabla Leticia Viedma Elicer
Abstract: The invention discloses the use of a composition comprising at least one nitric oxide generating agent for increasing production of and/or retention of a plant organ.
Type:
Application
Filed:
July 20, 2005
Publication date:
December 25, 2008
Applicants:
University of Sheffield, UNIVERSIDAD DE CHILE
Inventors:
Alejandro Andres Riquelme Escobar, Manuel Pinto, Peter Horton
Abstract: This invention reveals polypropylene composites to be used in the automotive, electronics, packaging and textile industries, which comprises a polypropylene homopolymer in a proportion ranging from 10 to 60% by weight, a natural reinforcement based on eggshells, and an antioxidant. This invention also reveals a natural reinforcement produced from eggshells obtained as an agroindustrial waste, the process to obtain said composite, and the process to obtain such reinforcement. By means of this invention, polypropylene composites using the natural reinforcement are obtained that have improved mechanical and thermal behavior when compared to polypropylene composites using traditional mineral reinforcements.
Type:
Grant
Filed:
September 28, 2005
Date of Patent:
December 2, 2008
Assignee:
Universidad de Chile
Inventors:
José Luis Arias Bautista, Juan Raúl Quijada Abarca, Patricio Fernando Toro Estay, Pedram Mehrdad Yazdani
Abstract: A method and a plant to remove metals by biosorption from mining or industrial effluents comprising: (a) subject the effluent to at least one first stage of pre-treatment, selecting among: precipitation by pH rising, solvent extraction or solvent extraction on emulsified membranes in order to reduce its load of metals to a concentration level that allows it to be treated by the next stage of biosorption, and (b) subject the liquid that has been previously in the stage of pre-treatment to a second stage of continuous metals removal by biosorption.
Type:
Application
Filed:
December 4, 2007
Publication date:
June 19, 2008
Applicants:
UNIVERSIDAD DE CHILE, BIOTECHNOLOGIAS DEL AGUA LTDA.
Inventors:
Davor Cotoras Tadic, Fernando Valenzuela Lozano, Miguel Esteban Zarzar Maza, Pabla Leticia Viedma Elicer
Abstract: A method and a plant to remove metals by biosorption from mining or industrial effluents comprising: (a) subject the effluent to at least one first stage of pre-treatment, selecting among: precipitation by pH rising, solvent extraction or solvent extraction on emulsified membranes in order to reduce its load of metals to a concentration level that allows it to be treated by the next stage of biosorption, and (b) subject the liquid that has been previously in the stage of pre-treatment to a second stage of continuous metals removal by biosorption.
Type:
Grant
Filed:
October 4, 2005
Date of Patent:
February 5, 2008
Assignees:
Universidad de Chile, Biotechnologias del Agua Ltda.
Inventors:
Davor Cotoras Tadic, Fernando Valenzuela Lozano, Miguel Esteban Zarzar Maza, Pabla Leticia Viedma Elicer
Abstract: This invention is referred to a new bacterial strain of Bacillus sp., to be applied in a metal biosorption process, which was deposited in the Agricultural Research Culture Collection (NRRL) International Depositary Authority, 1815 N. University Street, Peoria Ill. 61604, USA, having an accession number NRRL-B-30881. It is described, also, a sporulated and non-sporulated industrial inoculant of said bacterium, a method to produce said inoculant, and a process to remove metals by said bacterium.
Type:
Application
Filed:
June 26, 2007
Publication date:
January 10, 2008
Applicants:
UNIVERSIDAD DE CHILE, BIOTECNOLOGIAS DEL AQUA LTDA.
Abstract: A method and a plant to remove metals by biosorption from mining or industrial effluents comprising: (a) subject the effluent to at least one first stage of pre-treatment, selecting among: precipitation by pH rising, solvent extraction or solvent extraction on emulsified membranes in order to reduce its load of metals to a concentration level that allows it to be treated by the next stage of biosorption, and (b) subject the liquid that has been previously in the stage of pre-treatment to a second stage of continuous metals removal by biosorption.
Type:
Application
Filed:
October 4, 2005
Publication date:
April 6, 2006
Applicants:
UNIVERSIDAD DE CHILE, BIOTECNOLOGIAS DEL AQUA LTDA.
Inventors:
Davor Tadic, Fernando Valenzuela Lozano, Miguel Zarzar Maza, Pabla Viedma Elicer
Abstract: This invention reveals polypropylene composites to be used in the automotive, electronics, packaging and textile industries, which comprises a polypropylene homopolymer in a proportion ranging from 10 to 60% by weight, a natural reinforcement based on eggshells, and an antioxidant. This invention also reveals a natural reinforcement produced from eggshells obtained as an agroindustrial waste, the process to obtain said composite, and the process to obtain such reinforcement. By means of this invention, polypropylene composites using the natural reinforcement are obtained that have improved mechanical and thermal behavior when compared to polypropylene composites using traditional mineral reinforcements.
Type:
Application
Filed:
September 28, 2005
Publication date:
March 30, 2006
Applicant:
UNIVERSIDAD DE CHILE
Inventors:
Jose Arias Bautista, Juan Quijada Abarca, Patricio Toro Estay, Pedram Mehrdad Yazdani