Abstract: A method to change development of a plant or plant part, when compared to the wild-type plant or plant part, by increasing or decreasing expression in a plant or plant part of a cdc27a nucleic acid sequence and/or increasing or decreasing levels and/or activity in a plant of a CDC27A protein; a plant obtained by this method; a genetic construct for enacting the method; a food including the plant or plant part; an enzyme or pharmaceutical produced by the plant or plant part; and a method of making an enzyme or pharmaceutical by the plant or plant part.

Abstract: The present invention refers to the use of phthalimide and/or sulphonamide derivatives with nitric oxide donor properties, which have important activities in increasing the gamma-globin gene expression and anti-inflammatory and analgesic activities, effective in the treatment of hematologic diseases which require reducing the TNF-? levels and an exogenous source of nitric oxide. More particularly, the present invention describes the use of such phthalimide and/or sulphonamide derivatives for the treatment of sickle-cell disease. The invention also has as a novel characteristic the disclosure of new functionalized phthalimide derivatives designed from the prototypes thalidomide and hydroxyurea, and designed rationally through the strategy of molecular hybridization for the treatment of said diseases.

Abstract: The novelty proposed herein describes the application of niobium-based compositions and coatings, niobium oxides and their alloys capable of associations with other oxides and alloys by means of the thermal spraying technique for the purpose of an anticorrosive protection in highly corrosive environments, mainly those which present high temperatures, show presence of gases such as H2S, SO2, CO2, as well as organic and inorganic acids, commonly found in industrial centers.

Abstract: The present invention provides a method of increasing yield in plants, comprising transforming a plant with a nucleic acid encoding a CDC27 polypeptide or homolog thereof having a N-terminal deletion operably linked to a promoter active in the plant, where 100 to 220 amino acids are deleted at the N-terminus of the CDC27 polypeptide.

Abstract: The present invention describes a process to form hydrazides from the reaction of a hydrazine and a dicarboxylic, using a Lewis acid as a main reagent of the reaction. The reaction occurs in a safe reactional environment, utilizing smooth conditions, neither involving high temperatures nor high pressures, producing the desired products with high yields, between 90-95%. The invention also describes a kit for utilization of chemiluminescent substances, comprised of two solutions.

Abstract: The present invention refers to a global clock system for clusters or networks of computers implemented entirely in hardware. The system uses a specifically designed hierarchical network to distribute clock pulses that are used to increment time counters in the cluster' nodes. In addition, this network enables any node of the cluster to send a reset signal to the other nodes so that all local time counters are initialized simultaneously and remain automatically synchronized afterwards. In this way, each processor in the cluster is able to obtain the value of the global clock whenever accessing its own local time counter. The reset signal is the only function that is implemented in software.

Abstract: The present invention describes the use of pomolic acid, its derivatives and pharmaceutical preparations derived from them as anti-neoplasic agents in the treatment of multidrug resistant tumors. In relation to other drugs that present anti-MDR activity, these substances do not require the concomitant use of reversers to exert their anti-MDR activities.

Abstract: A method to change development of a plant or plant part, when compared to the wild-type plant or plant part, by increasing or decreasing expression in a plant or plant part of a cdc27a nucleic acid sequence and/or increasing or decreasing levels and/or activity in a plant of a CDC27A protein; a plant obtained by this method; a genetic construct for enacting the method; a food including the plant or plant part; an enzyme or pharmaceutical produced by the plant or plant part; and a method of making an enzyme or pharmaceutical by the plant or plant part.

Abstract: The present invention relates to at least partially purified protein, capable of modulating the DNA replication in plants, muteins thereof, DNA coding therefor and to a method to confer to one or more plant cells the capacity to provide such a protein or mutein. The invention also relates to plants, comprising the said DNA and the progeny thereof.

Abstract: The present invention refers to compositions and coatings, having the niobium, its oxides and possible associations with other oxides as a pigment, and its utilization carried out by the usual techniques of painting, acting as an anticorrosive to organic acids, particularly the naphthenic acids in sulfide medium, persistently present in the petrochemical industry.

Abstract: The objective of the present invention is the detection/monitoring of microorganisms present in the air, water or foodstuffs through the use of a fiber optic biosensor with an evanescent-field. A first concretization of the present invention concerns a method for detection of contamination by specific microorganisms through the use of the evanescent-field of a sensitive fiber optic characterized by stages of: a) exposing the evanescent-field of the sensitive fiber optic using an appropriate technique based on physical and chemical properties; (b) permitting immediate contact of the exposed evanescent-field obtained in the stage (a) with the sample to be examined, with the aforementioned sample having a form adequate so as to obtain the generation of an optical signal in response to the presence of microorganisms in the sample; and, (c) demodulating the optical signal generated in stage (b) and using this value to quantify the microorganisms through an appropriate method.

Abstract: The inhibition of the formation and development of amyloidoses, as well as the dissolution of amyloidoses in organisms is claimed. Methods for the diagnosis of amyloidoses using aromatic and heteroaromatic compounds having at least one electron-withdrawing groups are claimed.