Abstract: An inlaid timepiece component (1) including a body (10) made of a metallic and/or ceramic material including at least one hollow (11) forming the impression of a decoration (12). The at least one hollow is completely filled with successive strata (13, 14, 15) formed by an agglomeration of particles (16) via a cold metallisation in order to form a timepiece component (1) inlaid with at least one decoration (12).

Abstract: An optical element is provided. The optical element may comprise a material, the material being a matrix and a set of particles included in the matrix, the material having a molar fraction of SiO2 higher than or equal to 65 percent, each particle having a dimension smaller than or equal to 80 nanometers.

Abstract: A device for detecting a target molecule and/or measuring the concentration of a target molecule, which includes: a substrate at the surface of which is covalently attached a grafting molecule; at least one fluorescent probe including at least one receptor bonded to a polypeptide via a covalent bond; two fluorochromes Fa and Fb, in which the fluorochrome Fa is bonded to the receptor and fluorochrome Fb is bonded to the polypeptide; and the fluorochromes Fa and Fb form a FRET donor/acceptor pair, in which the polypeptide is bonded to the grafting molecule via a covalent bond. Also, a fluorescent probe and a method for detecting a target molecule and/or measuring the concentration of a target molecule.

Abstract: Process for conferring a protection against a pathogen upon a plant by elicitation by an aqueous composition, the active agents of which are extracted from edible fungi (parasol mushroom, pleurotus, button mushroom). An alkaline extraction is carried out, then an enzymatic hydrolysis, to obtain a fraction less than 100 kDa. The process consists in spraying the aerial parts of the plant with the composition obtained in this way; this thereby acts to combat cryptogamic diseases of plants such as vines, fruit trees, vegetable crops and cereals.

Abstract: An optical fibre having a functionalised distal exploration end including a sheath, and a ferrule rigidly connected to the sheath at the distal exploration end, characterised in that the distal exploration end has a functionalised head which is removably attached on the ferrule. Also, a method of assembling the optical fibre.

Abstract: A radio frequency micro-electromechanical switch (generally referred to using the acronyms RF MEMS) is described. Also described is a method of producing such an RF MEMS switch.

Abstract: The present invention relates to a chimeric protein comprising at least one human amyloid P component and at least one fragment of an Fc region of a human antibody, the human amyloid P component and the fragment of an Fc region with which it is associated being bound to each other by means of a hinge region.

Abstract: An interposer (16) and a substrate (10) incorporating the interposer (16) are provided. The interposer (16) includes one or more layers (18) and a cavity (20) defined in the one or more layers (18), the cavity (20) being configured as a waveguide for propagation of electromagnetic waves.

Abstract: Some embodiments relate to a generation device that includes: a pulsed laser source generating primary photons having at least one wavelength within pulses having time dissymmetry, a forming device(s) controlling the primary photons so as to generate a selective-polarization, focused input beam, and an optical fiber wherein the primary photons induce secondary photons having different wavelengths resulting from a raman conversion cascade and forming a wide-spectrum output beam having substantially constant energy.

Abstract: The invention relates to the use of a lectin that recognizes the fucose ? 1-2 galactose unit, as a first means for labeling and optionally a second means for labelling colorectal cancer stem cells, in particular a lectin that recognizes the T antigen, in order to carry out a method for the detection and optionally isolation of colorectal cancer stem cells, a method for the detection and optionally isolation of colorectal cancer stem cells for research purposes, and a method for the in vitro diagnosis of colorectal cancer recurrence risk and/or aggressiveness so as to define a prognostic value in order to make colorectal cancer therapy adjustments, as well as a kit comprising a lectin that recognizes the fucose ? 1-2 galactose unit and a lectin that recognizes the T antigen.

Abstract: An optical fibre for an ultrafast laser endoscope including at least the following structures: a hollow core, the periphery of which has an order of symmetry of at least six when considering axes of symmetry passing through the centre of the core and through the centre of convex shapes, seen from the centre of the core, the convex shapes at least partly making up the periphery of the core; an intermediate layer of cellular structure surrounding the core; a light conducting peripheral structure surrounding the intermediate layer of cellular structure; and an outer sheath surrounding the light-conducting peripheral structure. A particular advantage of the optical fibre is that it optimizes the emission of a high-power flux associated with fluorescence collection.

Abstract: A method and system for adjusting the profile of a laser wavefront formed by at least a laser beam to a desired laser wavefront profile, the laser beam or beams presenting random phases and intensities, comprises a mixing module, configured to generate, from interference phenomena among the laser beam or beams, a laser field, a second intensity measuring module configured to measure the mixed intensities of the laser field portions, a calculation unit configured to calculate one or several phase correction values of the phase of the laser beam or the phases of laser beams, from the intensities of the laser beams, the mixed intensities and one or several predetermined target phases, and a phase adjustment module configured to apply the phase correction value or values obtained from the calculation unit to the laser beam phases.

Abstract: A power switching cell, and associated multi-level converter, include an input port capable of receiving a switching control signal, an input transistor linked by the gate to the input port, and by the source to a reference voltage, a self-biasing circuit comprising a self-biasing transistor linked by the gate to the drain of the input transistor, and a resistor connected in parallel between the gate and the source of the self-biasing transistor, and in series between the drain of the input transistor and the source of the self-biasing transistor, a power transistor, linked by the gate to the source of the self-biasing transistor and by the drain to a power supply voltage, and an isolating transistor linked by the gate and by the source to the gate and to the source of the power transistor, and by the drain to the output port of the cell.

Abstract: A radio frequency micro-electromechanical switch (generally referred to using the acronyms RF MEMS) is described. Also described is a method of producing such an RF MEMS switch.

Abstract: An optical fibre having a functionalised distal exploration end including a sheath, and a ferrule rigidly connected to the sheath at the distal exploration end, characterised in that the distal exploration end has a functionalised head which is removably attached on the ferrule. Also, a method of assembling the optical fibre.

Abstract: Some embodiments are directed to a generating device, including a pulse laser source providing primary photons having at least one wavelength, shaping device(s) acting on the primary photons to provide an input beam, a nonlinear crystal, and controller(s) generating, in the nonlinear crystal, at least one electric field that is synchronous with the input beam and suitable for inducing a phase mismatching in the nonlinear crystal through an electro-optical effect, in order to convert the primary photons of the input beam into secondary photons having wavelengths belonging to a supercontinuum.

Abstract: A generating device includes at least one pulsed laser source that delivers primary photons having at least one wavelength in a single spatial mode and in pulses having a high pump energy, forming means that act on the primary photons to deliver an input beam, and at least one optical fiber having at least ten modes between which the pump energy is initially distributed, and able to relocate the latter via a non-linear effect into a fundamental mode, before generating secondary photons of various wavelengths by wavelength conversions from the wavelength of the primary photons in the fundamental spatial mode.

Abstract: A monomode optical fiber, and a process for manufacturing such a fiber, that comprises a monomode core and at least one cladding encircling the core. The monomode core comprises at least two zones, a first zone with at least one first refractive index and a second zone with at least one second refractive index different from the first refractive index. The difference between the first refractive index and the second refractive index is of the same order of magnitude as the variation in the refractive index of the second zone between the inactive state and the active state of the fiber.

Abstract: The present invention concerns a treatment of diseases involving B cells, B lymphocytes or plasmocytes. In particular, it concerns an antisense oligonucleotide or a mixture of antisense oligonucleotides capable of inducing exon skipping at the RNA of the immunoglobulin heavy or light chains, for the use of same in the treatment of diseases involving B cells.

Abstract: A method and system for adjusting the profile of a laser wavefront formed by at least a laser beam to a desired laser wavefront profile, the laser beam or beams presenting random phases and intensities, comprises a mixing module, configured to generate, from interference phenomena among the laser beam or beams, a laser field, a second intensity measuring module configured to measure the mixed intensities of the laser field portions, a calculation unit configured to calculate one or several phase correction values of the phase of the laser beam or the phases of laser beams, from the intensities of the laser beams, the mixed intensities and one or several predetermined target phases, and a phase adjustment module configured to apply the phase correction value or values obtained from the calculation unit to the laser beam phases.