Abstract: A combined machine for harvesting and shelling almonds is described, comprising a shelling machine combined with a harvesting machine, wherein the shelling machine is connected to the harvesting machine so that the outlet of the almonds harvested by the harvesting machine coincides with the loading area of the shelling machine; such combined machine allows directly performing in a field, and upon harvesting, the shelling of the almonds; the shelling machine is arranged transversally to the advancement direction of the harvesting machine and is connected to the top part of the harvesting machine, so that the end from which the shelled products go out bestrides the adjacent row to the row treated by the harvesting machine and the shelled almonds are poured into a trailer towed in an adjacent inter-row.

Abstract: The present invention relates to the field of biotechnologies and in particular to the use of a nucleotide sequence having transcription promoter activity in prokaryotic and eukaryotic cell systems.

Abstract: Described herein is a field effect transistor sensor including: a substrate, a source electrode, a drain electrode, a gate electrode functionalized with a layer of biological recognition elements, a source-drain channel and a semiconductor layer. The layer of biological recognition elements of the gate electrode is patterned into a plurality of uncoupled domains.

Abstract: A process and an apparatus for the plenoptic capture of photographic or cinematographic images of an object or a 3D scene (10) of interest are based on a correlated light emitting source and correlation measurement, along the line of “Correlation Plenoptic Imaging” (CPI). A first image sensor (Da) and a second image sensor (Db) detect images along a path of a first light beam (a) and a second light beam (b), respectively. A processing unit (100) of the intensities detected by the synchronized image sensors (Da, Db) is configured to retrieve the propagation direction of light by measuring spatio-temporal correlations between light intensities detected in the image planes of at least two arbitrary planes (P?, P?; D?b, D?a) chosen in the vicinity of the object or within the 3D scene (10).

Abstract: A process and device for the plenoptic capture of photographic or cinematographic images are described, both based on the correlation measure or “Correlation Plenoptic Imaging” (CPI), comprising the steps of splitting a primary light beam (6) coming from at least one light source in at least two distinct light beams (7, 8), directing said distinct light beams towards two image capturing sensors to capture images, so that the first light beam is directed towards at least one first capturing sensor to capture a spatial measure of a scene and the second light beam is directed towards a second capturing sensor to capture an angular measure of said scene, said angular measure being adapted to provide the propagation direction of the light beam coming from the scene, said spatial measure being adapted to provide the conventional two-dimensional capture of the image of the scene.

Abstract: Described herein is a field effect transistor sensor including: a substrate, a source electrode, a drain electrode, a gate electrode functionalized with a layer of biological recognition elements, a source-drain channel and a semiconductor layer. The layer of biological recognition elements of the gate electrode is patterned into a plurality of uncoupled domains.

Abstract: A process and device for the plenoptic capture of photographic or cinematographic images are described, both based on the correlation measure or “Correlation Plenoptic Imaging” (CPI), comprising the steps of splitting a primary light beam (6) coming from at least one light source in at least two distinct light beams (7, 8), directing said distinct light beams towards two image capturing sensors to capture images, so that the first light beam is directed towards at least one first capturing sensor to capture a spatial measure of a scene and the second light beam is directed towards a second capturing sensor to capture an angular measure of said scene, said angular measure being adapted to provide the propagation direction of the light beam coming from the scene, said spatial measure being adapted to provide the conventional two-dimensional capture of the image of the scene.

Abstract: An object of the present invention is the use of Irisin for the treatment and/or prevention of osteoporosis. In particular, the present invention refers to the use of recombinant irisin for the treatment and/or prevention of osteoporosis. A method for preventing and/or treating osteoporosis by administering an effective amount of irisin to a subject, is provided.

Abstract: A method of functionalization of a gate electrode of a field-effect transistor sensor includes forming a layer of biological recognition elements on a surface of said gate electrode, wherein said layer of biological recognition elements includes a self-assembled structure of one or more specific-binding-pair-forming substances (anti-hIg, anti-IgG, anti-IgM). The layer of biological recognition elements is treated with a solution containing a blocking agent to fill vacancies and prevent nonspecific binding in the self-assembled structure. One or more specific-binding-pair-forming substances immobilized in said layer of biological recognition elements are packed at a density of 0.1×104 ?m?2 and 10×104 ?m?2, preferably between 1×104 ?m?2 and 2×104 ?m?2.

Abstract: Object of the present invention is the use of a known protein, irisin, for preservation of the functionality and survival of the cells of the pancreatic islets.

Abstract: Object of the present invention is the use of selective agonists of beta-adrenergic type 3 receptors (BAR3) in the treatment of nephrogenic diabetes insipidus (NDI), in particular of X-linked nephrogenic diabetes insipidus (X-NDI).

Abstract: A transistor includes at least one conductive layer, at least one gate dielectric layer and at least one semiconducting film deposited on top of a receptor molecule layer previously deposited or covalently linked to the surface of the gate dielectric. The layer of biological material includes single or double layers of phospholipids, layers made of proteins such as receptors, antibodies, ionic channels and enzymes, single or double layers of phospholipids with inclusion or anchoring of proteins such as: receptors, antibodies, ionic channels and enzymes, layers made of oligonucleotide (DNA, RNA, PNA) probes, layers made of cells or viruses, layers made of synthetic receptors for example molecules or macromolecules similar to biological receptors for properties, reactivity or steric aspects.

Abstract: The invention relates to the use of 4,6,4?-trimethylangelicin (TMA) and structural analogs thereof to prepare a medicament for the treatment of cystic fibrosis with the primary objective of correcting the defective CFTR in a sub-group of cystic fibrosis patients consisting of patients carrying the F508del-CFTR mutation.

Abstract: The invention relates to a new class of compounds able to inhibit with high affinity and selectivity the 5-HT7 receptor and having the following formula IV: wherein W is O; K, L, M and Q is CH or nitrogen; R1 is hydrogen; R2 is hydrogen; and Ar is an aromatic ring with the following formula: wherein X, Y and Z is CH; and R3 is a five- or six-membered ring selected from the group consisting of:

Abstract: The invention relates to the use of 4,6,4?-trimethylangelicin (TMA) and structural analogues thereof to prepare a medicament for the treatment of cystic fibrosis with the primary objective of correcting the defective CFTR in a sub-group of cystic fibrosis patients consisting of patients carrying the F508de1-CFTR mutation.

Abstract: The invention relates to a new class of compounds with high affinity and selectivity towards P-glycoprotein. The invention also relates to the utilization of such compounds in the in vivo diagnosis of neurodegenerative diseases and as medicaments for use in the prevention and treatment of neurodegenerative disease involving P-glycoprotein.

Abstract: A transistor includes at least one conductive layer, at least one gate dielectric layer and at least one semiconducting film deposited on top of a receptor molecule layer previously deposited or covalently linked to the surface of the gate dielectric. The layer of biological material includes single or double layers of phospholipids, layers made of proteins such as receptors, antibodies, ionic channels and enzymes, single or double layers of phospholipids with inclusion or anchoring of proteins such as: receptors, antibodies, ionic channels and enzymes, layers made of oligonucleotide (DNA, RNA, PNA) probes, layers made of cells or viruses, layers made of synthetic receptors for example molecules or macromolecules similar to biological receptors for properties, reactivity or steric aspects.

Abstract: A pharmaceutical preparation treats Friedreich's ataxia and treats or prevents pathologies related thereto. In particular, the pharaceutical preparation concerns the use of diazoxide or 7-chloro-3-methyl-4H-1,2,4 benzothiadiazine 1,1-dioxide, in combination with glucose and/or leucine, for the treatment of Friedreich's ataxia (FRDA) and for the treatment or prevention of pathologies related thereto.

Abstract: The invention relates to a new class of compounds with high affinity and selectivity towards P-glycoprotein. The invention also relates to the utilization of such compounds in the in vivo diagnosis of neurodegenerative diseases and as medicaments for use in the prevention and treatment of neurodegenerative disease involving P-glycoprotein.

Abstract: The invention relates to a new class of compounds able to inhibit with high affinity and selectivity the 5-HT7 receptor. The invention also relates to the utilization of such compounds as medicaments useful in the treatment and prevention of 5-HT7 receptor relating disorders of the central nervous system. The invention also relates to the isotopically labeled compounds for use in vivo diagnosis or imaging of a 5-HT7 condition.