Abstract: A protein toxin named Aeromonas salmonicida exoenzyme T (AexT), which belongs to the family of ADP-ribosylating toxins, is disclosed as is a novel Calcium (or other cation concentration) dependent promoter of A. salmonicida. Also disclosed are diagnostic, preventive, and therapeutic techniques, including the preparation of bacterin vaccines based on AexT for inducing immunity against A. salmonicida infections.

Abstract: A novel protein toxin named Aeromonas salmonicida exoenzyme T (AexT), which belongs to the family of ADP-ribosylating toxins, is disclosed as is a novel Calcium (or other cation concentration) dependent promoter of A. salmonicida. Also disclosed are diagnostic, preventative, and therapeutic techniques, including the preparation of traditional, recombinant, and improved bacterin vaccines based on AexT for inducing immunity against A. salmonicida infections.

Abstract: Disclosed is a newly identified and characterized type III secretion system in Aeromonas salmonicida. The invention also encompasses the use of components of the novel secretion system in immunoprotection against A. salmonicida infection, as well as other diagnostic and therapeutic uses thereof.

Abstract: The present invention relates to compounds having a decaline scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said decaline-derived compounds can be used for prophylaxsis and/or treatment of diabetes mellitus type I, diabetes mellitus type II, tuberculosis and other infectious diseases, proliferative diseases, cancer, neurodegenerative diseases, obesity, cognitive dysfunctions and metabolic syndromes.

Abstract: An implant for sealing and/or healing a defect in an annulus having an area intended to encompass the defect. The implant is a textile strip that has a middle area which is intended to encompass the defect and which is an oriented low-density embroidered structure for guided tissue ingrowth and reinforcement and end areas adjacent to the middle area which are a high-density embroidered structure.

Abstract: An oriented zeolite material comprises a plurality of zeolite crystals (2) arranged on a substrate (4), each one of said crystals having a proximal face (6) adjacent to said substrate and a distal face (8) opposed therefrom and substantially parallel to said proximal face. Each one of said crystals has a plurality of straight through uniform channels (10) extending between the proximal face and the distal face and having a channel axis parallel to and a channel width transverse to a longitudinal crystal axis A. Each channel has a proximal channel end (12) located at the proximal face and a distal channel end (14) located at the distal face, and each crystal is attached to the substrate by means of a linking layer (16) that substantially occludes the proximal channel ends.

Abstract: A protein toxin named Aeromonas salmonicida exoenzyme T (AcxT), which belongs to the family of ADP-ribosylating toxins, is disclosed as is a Calcium (or other cation concentration) dependent promoter of A. salmonicida. Also disclosed are diagnostic, preventive, and therapeutic techniques, including the preparation of bacterin vaccines based on AexT for inducing immunity against A. salmonicida infections.

Abstract: Disclosed is a newly identified and characterized type III secretion system in Aeromonas salmonicida. The invention also encompasses the use of components of the novel secretion system in immunoprotection against A. salmonicida infection, as well as other diagnostic and therapeutic uses thereof.

Abstract: Radionuclide labelled conjugates based on substance P and analogues thereof with the chelator (DOTAGA) (1-(1-rarboxy-3-carboxy-propyl)-4,7,10(carboxymethyl)-1,4,7,10-tetraazacyclo-dodecane, DOTASA (1-(1-carboxy-2carboxy-ethyl)-4,7,10(carboxymethyl)1,4,7,10-tetraazacyclo-dodecane, or chelator (DOTA) [1,4,7,10 tetraazaacyclo-dodecane 1,4,7,10-tetra(acetic acid)] are useful radiopharmaceutical substances for targeting and treatment of brain tumors, especially gliomas.

Abstract: Disclosed is an array for modifying a wavefront of an optical beam (3) having a beam axis (15). Said array comprises an influencing unit (1) which can be introduced into the beam path of the optical beam (3) and a heat source (12) that generates a thermal pattern and acts upon the influencing unit (1). The influencing unit (1) is provided with at least one planar cooling plate (7a, 7b) that extends transversal to the optical axis (15) of the incident beam (3) and a fluid layer or gel layer (9) which has a two-dimensional expansion, is disposed on the cooling plate with a basal surface, and absorbs the heat of the heat source. The two-dimensional expansion is large enough to receive approximately the entire cross section of the beam.

Abstract: A method for compensating thermal optical effects in the beam path of an arrangement containing optical components uses, for the purpose of optical compensation in the beam path, optical elements which have different material properties in cooperation. For the purpose of compensation, heating by means of radiation absorption, radial thermal conduction for generating a power-dependent temperature distribution, and/or thermal dispersion for generating a thermal lens are distributed over the different elements.

Abstract: The present invention is concerned with nutritional or pharmaceutical compositions containing an extract or concentrate of a plant from the genus Lycopersicon. The compositions of the invention are useful for the treatment or prophylaxis of diseases or conditions which are characterized by increased bone resorption, such as Paget's disease, tumor-induced bone disease or particularly osteoporosis.

Abstract: A method for generating polarized laser output radiation utilizes a laser resonator whose active medium exhibits thermally induced birefringence. The radiation fields oscillating in the laser resonator are not subjected to polarization selection, and only the radiation field exhibiting the desired polarization state (p) is partially output. Only a prescribed polarization of the radiation fields of the laser radiation which can oscillate in the resonator can be partially output from the resonator with a prescribed output level and all differently polarized radiation fields remain in the resonator in a completely reflecting fashion.

Abstract: The present invention is concerned with nutritional or pharmaceutical compositions containing a plant extract or concentrate selected from the group consisting of allium (leek), aethusa (dog parsley), petroselium (parsley) and brassica (cabbage) extracts and concentrates. The compositions of the invention are useful for the treatment or prophylaxis of diseases or conditions which are characterized by increased bone resorption, such as Paget's disease, tumor-induced bone disease or particularly osteoporosis.

Abstract: The present invention is concerned with nutritional or pharmaceutical compositions containing an extract or concentrate of a plant from the genus anethum. The compositions of the invention are useful for the treatment or prophylaxis of diseases or conditions which are characterized by increased bone resorption, such as Paget's disease, tumor-induced bone disease or particularly osteoporosis.

Abstract: A semiconductor device comprising, a plurality of semiconductor layers having an outer semiconductor layer, and a contact layer uniformly and entirely covering said outer semiconductive layer and having over its entire surface the same material composition and abutting over its entire surface directly against said outer semiconductive layer but having only on a partial region of its surface a conductive transition to said outer semiconductive layer. The conductive transition being obtained by alloying said partial region by means of a focused laser beam pulse heating only said partial region of the contact layer to the alloying temperature, whereby alloy constituents of the melted contact material wetting said outer semiconductive layer diffuse only in a superficial zone of said outer semiconductive layer.

Abstract: An apparatus for sieve filtration, and in particular ultrafiltration using a membrane as the filter, is particularly useful for filtering extremely small initial volumes, in particular of blood plasma or serum, in a pressurized cell with alternating flow direction of the liquid to be filtered, thus preventing concentration polarization, and preventing contact of the liquid to be filtered with any foreign substance such as a pressure gas.