Patents Assigned to Universite Claude Bernard Lyon I
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Patent number: 11873763Abstract: An acoustic treatment grid intended to be mounted inside or at the outlet of a duct of a bleed valve of a turbomachine of an aircraft intended to convey a gas flow, the grid comprising a perforated plate and circular orifices traversing the perforated plate along a first direction, the orifices having a diameter and a geometrical center. Each orifice is separated from an adjacent orifice by a space, the length of which is equal to the product of the diameter of said orifice and a spacing coefficient of a value between 1.1 and 6.Type: GrantFiled: April 7, 2021Date of Patent: January 16, 2024Assignees: SAFRAN AIRCRAFT ENGINES, ECOLE CENTRALE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON IInventors: Paul Clément Guillaume Laffay, Fernando Gea Aguilera, Josselin David Florian Regnard, Marc Cornelius Jacob, Stéphane Moreau
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Publication number: 20230264183Abstract: Nanoparticles that can be used as hydrosilylation and dehydrogenative silylation catalysts. The nanoparticles have at least one transition metal with an oxidation state of 0, chosen from the metals of columns 8, 9 and 10 of the periodic table, and at least one carbonyl ligand, preferably a silicide.Type: ApplicationFiled: March 20, 2023Publication date: August 24, 2023Applicants: ELKEM SILICONES FRANCE SAS, UNIVERSITE CLAUDE BERNARD LYON I, CPE LYON FORMATION CONTINUE ET RECHERCHE - CPE LYON CFR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRSInventors: Valérie MIELLE, Chloé THIEULEUX, Laurent VEYRE, Iurii SULEIMANOV, Thomas GALEANDRO-DIAMANT, Magali BOUSQUIE
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Publication number: 20230151769Abstract: An acoustic treatment grid intended to be mounted inside or at the outlet of a duct of a bleed valve of a turbomachine of an aircraft intended to convey a gas flow, the grid comprising a perforated plate and circular orifices traversing the perforated plate along a first direction, the orifices having a diameter and a geometrical center. Each orifice is separated from an adjacent orifice by a space, the length of which is equal to the product of the diameter of said orifice and a spacing coefficient of a value between 1.1 and 6.Type: ApplicationFiled: April 7, 2021Publication date: May 18, 2023Applicants: SAFRAN AIRCRAFT ENGINES, ECOLE CENTRALE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON IInventors: Paul Clément Guillaume LAFFAY, Fernando GEA AGUILERA, Josselin David Florian REGNARD, Marc Cornelius JACOB, Stéphane MOREAU
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Patent number: 11633728Abstract: Nanoparticles that can be used as hydrosilylation and dehydrogenative silylation catalysts. The nanoparticles have at least one transition metal with an oxidation state of 0, chosen from the metals of columns 8, 9 and 10 of the periodic table, and at least one carbonyl ligand, preferably a silicide.Type: GrantFiled: January 11, 2019Date of Patent: April 25, 2023Assignees: ELKEM SILICONES FRANCE SAS, UNIVERSITE CLAUDE BERNARD LYON I, CPE LYON FORMATION CONTINUE ET RECHERCHE—CPE LYON CFR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRSInventors: Valerie Meille, Chloe Thieuleux, Laurent Veyre, Iurii Suleimanov, Thomas Galeandro-Diamant, Magali Bousquie
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Publication number: 20230124079Abstract: Discharge grate intended to be mounted inside or at the outlet of a conduit of a discharge valve of a turbine engine of an aircraft, the discharge grate comprising an upstream face intended to receive a gas flow, a downstream face parallel to the upstream face and intended to deliver the gas flow received on the upstream face, and orifices passing through the perforated plate from the upstream face to the downstream face and intended to convey the gas flow through the perforated plate. The discharge grate comprises for each orifice of the perforated plate a tubular channel, coaxial with the orifice with which it is associated, and projecting from the downstream face of the perforated plate.Type: ApplicationFiled: April 6, 2021Publication date: April 20, 2023Applicants: SAFRAN AIRCRAFT ENGINES, ECOLE CENTRALE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON IInventors: Josselin David Florian REGNARD, Paul Clément Guillaume LAFFAY, Marc Cornelius JACOB, Stéphane MOREAU
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Patent number: 11529316Abstract: The invention relates to a novel use of ultrafine nanoparticles, of use as a diagnostic, therapeutic or theranostic agent, characterized by their mode of administration via the airways. The invention is also directed toward the applications which follow from this novel mode of administration, in particular for imaging the lungs, and the diagnosis or prognosis of pathological pulmonary conditions. In the therapeutic field, the applications envisioned are those of radiosensitizing or radioactive agents for radiotherapy (and optionally curietherapy), or for neutron therapy, or of agents for PDT (photodynamic therapy), in particular for the treatment of lung tumors.Type: GrantFiled: December 6, 2019Date of Patent: December 20, 2022Assignees: Universite Claude Bernard Lyon I, Nano-H, Centre National de la Recherche Scientifique—CNRS, Universite Grenoble Alpes, Universite de BordeauxInventors: Yannick Cremillieux, Andrea Bianchi, Sandrine Dufort, Jean-Luc Coll, Francois Lux, Olivier Tillement
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Publication number: 20220244171Abstract: The invention provides for methods and systems involving the measurement of values of one or several characterizing parameters representative of the kinetics of an assay chemical reaction, including providing a calibration tool (26) comprising a reaction chamber (28); for a given set of defining features, performing a series of calibration experiments under different sets of calibration values of at least one operating parameter, providing a digital calibration model representative of the kinetics of the assay chemical reaction in the calibration tool, where the assay digital calibration model comprises one or several characterizing parameters, the values of which have a dependency on the given set of defining features used for the calibration experiments; fitting, by computation, the values of the characterizing parameters for the given set of defining features, based on the series of calibration experiment results, wherein the reaction chamber (28) is a stirred-tank reactor.Type: ApplicationFiled: May 22, 2019Publication date: August 4, 2022Applicants: BIOMÉRIEUX, UNIVERSITE CLAUDE BERNARD LYON I, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Laurent DRAZEK, Christian JALLUT, Isabelle PITAULT, Maëlenn ROBIN, Mélaz TAYAKOUT-FAYOLLE
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Publication number: 20210206938Abstract: A method for producing a porous silicone material including the following steps: 1) implementing a direct emulsion E of silicone in water including: A) a silicone base A crosslinkable by polyaddition or polycondensation; B) at least one nonionic silicone surfactant B having a cloud point between 10 and 50° C.; C) optionally, at least one catalyst C; and D) water; 2) heating the emulsion E to a temperature greater than or equal to 60° C. to obtain a porous silicone material; and 3) optionally, drying the porous silicone material.Type: ApplicationFiled: May 17, 2019Publication date: July 8, 2021Applicants: Elkem Silicones France SAS, Institut National des Sciences Appliquees de Lyon, Universite Claude Bernard Lyon I, Centre National de la Recherche Scientifique - CNRS, Universite Jean Monnet Saint EtienneInventors: Francois GANACHAUD, Etienne FLEURY, Gabriel LARRIBE, David MARIOT, Frederic MARCHAL
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Publication number: 20200353454Abstract: Nanoparticles that can be used as hydrosilylation and dehydrogenative silylation catalysts. The nanoparticles have at least one transition metal with an oxidation state of 0, chosen from the metals of columns 8, 9 and 10 of the periodic table, and at least one carbonyl ligand, preferably a silicide.Type: ApplicationFiled: January 11, 2019Publication date: November 12, 2020Applicants: Elkem Silicones France SAS, Universite Claude Bernard Lyon I, CPE Lyon Formation Continue et Recherche - CPE Lyon FCR, Centre National de la Recherche Scientifique - CNRSInventors: Valerie MEILLE, Chloe THIEULEUX, Laurent VEYRE, Iurii SULEIMANOV, Thomas LEANDRO-DIAMANT, Magali BOUSQUIE
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Patent number: 10696694Abstract: The invention relates to cationic complexes made up of a lanthanide ion Ln3+ and a ligand of formula (I): with X, Y and R1 as defined in claim 1, and to the salts thereof with an anion, the solvates and hydrates thereof; with the exception of cationic complexes made up of a lanthanide ion Ln3+ and a ligand of one of formulae (I.1) or (I.4) as defined in claim 1, and the salts, solvates and hydrates thereof. The invention also relates to the use of such a complex or of a cationic complex made up of a lanthanide ion Ln3+ and a ligand of formula (I.1) or (I.4) as defined in claim 1, or of one of the salts thereof with an anion, the solvates or hydrates thereof, as an aid to the crystallisation of a biological macromolecule, as well as to crystallisation methods and methods for analysing or determining the structure of a biological macromolecule.Type: GrantFiled: December 16, 2016Date of Patent: June 30, 2020Assignees: ECOLE NORMALE SUPERIEURE LE LYON, UNIVERSITE CLAUDE BERNARD LYON I, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Oliver Maury, Eric Girard, Sylvain Engilberge, François Riobe
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Publication number: 20200108155Abstract: The invention relates to a novel use of ultrafine nanoparticles, of use as a diagnostic, therapeutic or theranostic agent, characterized by their mode of administration via the airways. The invention is also directed toward the applications which follow from this novel mode of administration, in particular for imaging the lungs, and the diagnosis or prognosis of pathological pulmonary conditions. In the therapeutic field, the applications envisioned are those of radiosensitizing or radioactive agents for radiotherapy (and optionally curietherapy), or for neutron therapy, or of agents for PDT (photodynamic therapy), in particular for the treatment of lung tumors.Type: ApplicationFiled: December 6, 2019Publication date: April 9, 2020Applicants: Universite Claude Bernard Lyon I, Nano-H, Centre National de la Recherche Scientifique - CNRS, Universite Grenoble Alpes, Universite de BordeauxInventors: Yannick CREMILLIEUX, Andrea BIANCHI, Sandrine DUFORT, Jean-Luc COLL, Francois LUX, Olivier TILLEMENT
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Patent number: 10517962Abstract: The invention relates to a novel use of ultrafine nanoparticles, of use as a diagnostic, therapeutic or theranostic agent, characterized by their mode of administration via the airways. The invention is also directed toward the applications which follow from this novel mode of administration, in particular for imaging the lungs, and the diagnosis or prognosis of pathological pulmonary conditions. In the therapeutic field, the applications envisioned are those of radiosensitizing or radioactive agents for radiotherapy (and optionally curietherapy), or for neutron therapy, or of agents for PDT (photodynamic therapy), in particular for the treatment of lung tumors.Type: GrantFiled: April 12, 2013Date of Patent: December 31, 2019Assignees: Universite Claude Bernard Lyon I, Nano-H, Universite Grenoble Alpes, Universite de Bordeaux, Centre National de la Recherche ScientifiqueInventors: Yannick Cremillieux, Andrea Bianchi, Sandrine Dufort, Jean-Luc Coll, Francois Lux, Olivier Tillement
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Patent number: 10440947Abstract: The present invention relates to an aqueous solution for organ preservation, in particular for the myocardium, the solution comprising: 100 mM to 130 mM of Na+; 12 mM to 15 mM of K+; 0.25 mM to 1.3 mM of Ca++; 0.5 ?M to 1.5 ?M of cyclosporin A; and 0.5 ?M to 1.5 ?M of taxol, and it also relates to the joint use of cyclosporin A and taxol in a solution for in vitro preservation of an organ, in particular the myocardium.Type: GrantFiled: November 13, 2014Date of Patent: October 15, 2019Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE CLAUDE BERNARD LYON IInventor: Rene Ferrera
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Patent number: 10370254Abstract: A process for obtaining borazane (NH3—BH3) includes introducing anhydrous liquid ammonia (NH3(l)) into a reactor thermostatically regulated to between a temperature ?1 and 40° C.; introducing, with stirring, into the reactor an amine borane complex (Am.BH3), the corresponding amine (Am) of which is soluble in anhydrous liquid ammonia only to a proportion of less than 10 g in 100 g of ammonia at 20° C., being introduced in an amount such that the mole ratio R=(NH3(l))/(Am.BH3) is greater than or equal to 5; stirring the mixture; stopping the stirring to obtain two demixed phases: a light phase constituted essentially of a solution of anhydrous liquid ammonia (NH3(l)) containing borazane; and a heavy phase constituted essentially of the amine corresponding to the amine borane complex introduced; isolating the borazane and drying under vacuum thereof; the temperature ?1 being greater than or equal to the melting point of the amine borane complex.Type: GrantFiled: May 22, 2015Date of Patent: August 6, 2019Assignees: AIRBUS SAFRAN LAUNCHERS SAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON IInventors: Guy M. Jacob, Henri R. Delalu, Ahmad A. El Hajj
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Patent number: 10179929Abstract: The invention provides probes with formula (I): in which: X1?NH, O, or S; X2?O or S; SE is a labile group, which may be eliminated under the action of a stimulus that may in particular be the presence of an enzyme, a chemical compound, or a physicochemical characteristic of the medium in which the probe is located; A is an aromatic group that, following cleavage of the C(X2)—O bond in aqueous solution, leads to the liberation of a chromophore or a fluorophore, R represents a hydrogen atom or -(L)n-GP, in which n is equal to 0 or 1, L is a linker arm, and GP is a hydrosolubilizing group; as well as their physiologically acceptable salts, solvates, or hydrates. The invention also provides intermediates for the synthesis thereof and detection methods employing them.Type: GrantFiled: June 24, 2015Date of Patent: January 15, 2019Assignees: ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE CLAUDE BERNARD LYON I, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jens Hasserodt, Maxime Prost
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Publication number: 20180362550Abstract: The invention relates to cationic complexes made up of a lanthanide ion Ln3+ and a ligand of formula (I) : with X, Y and R1 as defined in claim 1, and to the salts thereof with an anion, the solvates and hydrates thereof; with the exception of cationic complexes made up of a lanthanide ion Ln3+ and a ligand of one of formulae (I.1) or (I.4) as defined in claim 1, and the salts, solvates and hydrates thereof. The invention also relates to the use of such a complex or of a cationic complex made up of a lanthanide ion Ln3+ and a ligand of formula (I.1) or (I.4) as defined in claim 1, or of one of the salts thereof with an anion, the solvates or hydrates thereof, as an aid to the crystallisation of a biological macromolecule, as well as to crystallisation methods and methods for analysing or determining the structure of a biological macromolecule.Type: ApplicationFiled: December 16, 2016Publication date: December 20, 2018Applicants: ECOLE NORMALE SUPERIEURE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON I, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Oliver MAURY, Eric GIRARD, Sylvain ENGILBERGE, François RIOBE
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Patent number: 10126261Abstract: A method to determine an electronic signature characteristic of a fluid medium comprises making a reception surface for receiving the fluid medium on at least one face of the substrate, putting the fluid medium into contact with the reception surface in order to make an interface between the substrate and the fluid medium, lighting at least one zone of the interface through the fluid medium with a pulsed light beam in order to create photogenerated electric charges, using a microwave reflectometer to measure the lifetime durations of the photogenerated electric charges, which durations have respective values that depend on the recombination rate at the interface between the substrate and the fluid medium, creating a matrix of measured lifetime duration values for the photogenerated electric charges, and using the matrix to determine the electronic signature characteristic of the fluid medium.Type: GrantFiled: December 17, 2013Date of Patent: November 13, 2018Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE CENTRALE DE LYON, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARD LYON I, UNIVERSITE T. CHEVTCHENKO DE KIEVInventors: Sergeii Lytvynenko, Sergei Alexandrovich Alekseyev, Volodymyr Lysenko, Valeriy Skryshevskyy
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Patent number: 10088534Abstract: A measurement device for magnetic resonance applications includes, in a measurement case: a first sensor for measuring radiofrequency magnetic fields; a second sensor for measuring magnetic field gradients; and a third sensor for measuring the radiofrequency electric field; and a stage for converting the electric signals delivered by the different measurement sensors into light signals. The device also in a controller for controlling and processing the signals, connected to the stage for conditioning the measurement case via a beam for transmitting light signals. The controller includes a stage for converting light signals into electric signals delivered by the sensors.Type: GrantFiled: February 12, 2014Date of Patent: October 2, 2018Assignees: UNIVERSITE CLAUDE BERNARD LYON I, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES 1Inventors: Hervé Saint-Jalmes, Olivier Beuf
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Patent number: 10047106Abstract: The present invention relates to luminescent lanthanide complexes including a chelating agent, formed with a macrocycle or a set of ligands, complexing a lanthanide ion Ln3+, wherein the chelating agent is substituted with at least two groups. The invention is most particularly applied to lanthanide complexes, the chelating agent of which is formed the with three ligands integrating a 2,6 pyridine-di(carboxylic acid) or is formed with a macrocycle having a 1,4,7 triazacyclononane structure.Type: GrantFiled: April 3, 2014Date of Patent: August 14, 2018Assignees: ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE CLAUDE BERNARD LYON I, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Olivier Maury, Chantal Andraud, Virginie Placide, Delphine Pitrat
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Patent number: 9963477Abstract: The invention relates to a method for the isomerization of glucose into fructose in water in the presence of a solid base catalyst characterized by its reversibility of CO2 adsorption at a low temperature, the catalyst being a catalyst comprising at least one supported or non-supported lanthanide oxide or a molecular sieve based on silicon containing the organic template thereof. The invention also relates to a method for preparing HMF from glucose, comprising the isomerization of glucose into fructose.Type: GrantFiled: August 24, 2012Date of Patent: May 8, 2018Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE CLAUDE BERNARD LYON IInventors: Nadine Essayem, Rodrigo Lopes De Souza, Franck Rataboul, Cyril Feche, Dilson Cardoso, Demian Patrick Fabiano