Patents Assigned to Universite de Lorraine
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Patent number: 10891728Abstract: A method is provided for identifying an isthmus in a three-dimensional map of a cardiac cavity by means of a processing unit configured to perform the following steps: a) correlation between a set of stimulated points of the cardiac cavity, each stimulated point being represented by a set of signals that are obtained following surface electrocardiography (ECG), excluding ventricular tachycardia; b) identification of a watershed line on the basis of the above correlation results and of the 3D coordinates of the stimulated points in the 3D map; and c) determination of the isthmus based on a 3D corridor substantially transverse to the watershed line.Type: GrantFiled: April 1, 2016Date of Patent: January 12, 2021Assignees: UNIVERSITE DE LORRAINE, CENTRE HOSPITALIER REGIONAL DE NANCYInventor: Christian De Chillou
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Publication number: 20200397018Abstract: A process for producing a protein isolate from an oilseed meal, and the isolate thus obtained, said isolate comprising proteins and an amount of 4 wt. % or less of phytic acid, said amount of phytic acid being by weight of proteins in said isolate. The process may comprise the following steps: a) providing an oilseed meal; b) mixing the oilseed meal with a first aqueous solvent to form a slurry at a pH ranging from 6 to 7.8, said slurry having a solid phase; c) separating said solid phase from said slurry, d) mixing said separated solid phase with a second aqueous solvent at a pH ranging from 1 to 3.Type: ApplicationFiled: November 14, 2018Publication date: December 24, 2020Applicants: Avril, Universite de Lorraine, Centre National de la Recherche ScientifiqueInventors: Claire DEFAIX, Romain KAPEL, Olivier GALET
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Patent number: 10854807Abstract: Some embodiments are directed to a piezoelectric sensor, including a body with a central cavity; and a membrane extending over the cavity, which membrane is fastened to the body via its periphery and includes a carrier layer made of polymer and a sensitive layer made of piezoelectric polymer, the membrane being able to deform or vibrate. The sensitive layer is made of a material including a polymer filled with inorganic nanomaterials. Instrument including such a sensor.Type: GrantFiled: March 24, 2016Date of Patent: December 1, 2020Assignee: UNIVERSITÉ DE LORRAINEInventors: Didier Rouxel, Brice Vincent, Laurent Badie
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Patent number: 10844459Abstract: A method for extracting the tantalum from an acid aqueous phase A1 comprising at least one step comprising the bringing of the aqueous phase A1 into contact with a phase A2 not miscible with water, and then the separation of the aqueous phase A1 from the phase A2, the phase A2 consisting of one ionic liquid or a mixture of ionic liquids as an extractant. A method for recovering the tantalum that implements this extraction method and to a use of an ionic liquid or of a mixture of ionic liquids as an extractant, in order to extract the tantalum from such an aqueous phase A1.Type: GrantFiled: August 10, 2016Date of Patent: November 24, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, UNIVERSITE DE CHAMBERY, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, TND, UNIVERSITE DE LORRAINEInventors: Raphael Turgis, Guilhem Arrachart, Stéphane Pellet-Rostaing, Micheline Draye, Sophie Legeai, David Virieux, Christian Thomas
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Patent number: 10751947Abstract: An additive manufacturing device processes voxels representing an object to be additively manufactured by determining two graphs depending on whether the voxels indicate full or empty spaces, and redefines some of the voxels indicating an empty space as full spaces in order to ensure mechanical stability.Type: GrantFiled: June 28, 2016Date of Patent: August 25, 2020Assignees: Inria Institut National De Recherche En Informatique et en automatique, Universite De LorraineInventors: Sylvain Lefebvre, Jeremie Dumas, An Lu
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Patent number: 10755828Abstract: A device for preparing radioactive solutions, in particular radiopharmaceutical solutions, including: a movable support block with at least two cells capable of accommodating a vial; and a shielded covering, including a side wall surrounding the periphery of the support block and an upper wall covering the upper face of the support block, an opening being provided in the upper wall of the covering. A means for driving the support block is configured to selectively displace the support block into positions, referred to as working positions, in which a given cell is aligned with the opening to allow access to the cell from the outside of the covering. The support block is configured such that it can be further brought to a position, referred to as closing position, in which the opening is sealed by a shielded element carried by the support block.Type: GrantFiled: December 5, 2017Date of Patent: August 25, 2020Assignee: UNIVERSITE DE LORRAINEInventors: Guénolé Mathias-Laot, Quentin Thomas
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Patent number: 10658561Abstract: A thermoelectric element, particularly for a thermoelectric converter, includes an assembly of constituent layers comprising a central layer made of p- or n-type thermoelectric material, then, in an assembly direction, and on each side of said central layer, an intermediate layer forming a diffusion barrier followed by a buffer layer made of composite metal material. The buffer layers are intended to be secured to metal electrodes, characterized in that the cumulative thickness of the two buffer layers is greater than or equal to 50% of the thickness of the central layer, and preferably greater than or equal to 100% of the thickness of the central layer and very preferably greater than or equal to 200% of the thickness of the central layer, and in that the constituent material of the buffer layers is an alloy of two metals chosen from the family: TixAg1-x, VxFe1-x, VxAg1-x, TixFe1-x, where 0<x<1.Type: GrantFiled: August 18, 2016Date of Patent: May 19, 2020Assignees: UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Alexandre Jacquot, Bertrand Lenoir, Eugen Geczi, Iurii Kogut, Driss Kenfaui, Philippe Masschelein
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Patent number: 10619494Abstract: A part include a refractory alloy including a niobium matrix having metal silicide inclusions present therein, the surface of the part being coated by a protective coating, the protective coating including a phase having the following stoichiometry: (NbxTi1-x)3M?Cr?Si?X? where M designates Fe, Co, or Ni, X designates one or more other elements that might be present, x lies in the range 0 to 1, x lies in the range 5 to 8.5, and the sum ?+? lies in the range 3 to 7; or Nb4M??Si?X??? where M? designates Fe, Co, or Ni, X? designates one or more other elements that might be present, ? lies in the range 3.2 to 4.8, and ? lies in the range 6 to 8.Type: GrantFiled: May 21, 2018Date of Patent: April 14, 2020Assignees: SAFRAN AIRCRAFT ENGINES, UNIVERSITE DE LORRAINEInventors: Stéphane Knittel, Stéphane Mathieu, Michel Vilasi
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Patent number: 10603357Abstract: A polypeptide comprising one or more sequences derived from CDR2 or CDR3 of a TREM-1 protein, characterised by the ability to treat, ameliorate, or lessen the symptoms of conditions including sepsis, septic shock or sepsis-like conditions and IBD.Type: GrantFiled: December 14, 2015Date of Patent: March 31, 2020Assignees: Bristol-Myers Squibb Company, Universite de LorraineInventors: Gilbert Faure, Sebastien Gibot, Paola Panina, Nadia Passini
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Patent number: 10548494Abstract: A method is provided for determining a personalized cardiac model, including steps of (i) computing a velocity time profile of a blood flow across a selected area of the heart or the aorta during at least one cardiac cycle, using data acquired with a Magnetic Resonance Imaging (MRI) device; (ii) performing a segmentation of the velocity time profile so as to identify cardiac phases according to a predefined generic cardiac model; and (iii) computing normalized time location and/or duration of the cardiac phases within cardiac cycles so as to define a personalized cardiac model.Type: GrantFiled: January 7, 2014Date of Patent: February 4, 2020Assignees: UNIVERSITE DE LORRAINE, CENTRE HOSPITALIER REGIONAL DE NANCYInventors: Christophe Meyer, Pierre-André Vuissoz, Laurent Bonnemains, Jacques Felblinger
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Publication number: 20200011572Abstract: Thermoregulated multilayer material characterized in that it comprises at least one substrate and one thermoregulated layer, said thermoregulated multilayer material having: for ? radiation of between 0.25 and 2 ?m, an absorption coefficient ?m?0.8; and, for incident ? radiation of between 7.5 and 10 ?m, a reflection coefficient ?m: ?m?0.85, when the temperature T of said multilayer material 1 is ?100° C.; ?m between 0.3 and 0.85, when the temperature T of said multilayer material is between 0 and 400° C.Type: ApplicationFiled: March 12, 2018Publication date: January 9, 2020Applicants: VIESSMANN FAULQUEMONT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LORRAINEInventors: David Mercs, Fabien Capon, Nicolas Portha, Alexis Boileau
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Publication number: 20200000856Abstract: The disclosure relates to human mesenchymal stem cells from Wharton's jelly, a method for preparing them, and the therapeutic uses thereof, in particular for the treatment of sepsis and specifically septic shock. The treatment may involve the administration to a subject in need thereof a pharmaceutical composition including the human mesenchymal stem cells from Wharton's jelly and a pharmaceutically acceptable excipient.Type: ApplicationFiled: February 28, 2018Publication date: January 2, 2020Applicants: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER RÉGIONAL UNIVERSITAIRE DE NANCYInventors: Danièle BENSOUSSAN, Sébastien GIBOT, Loïc REPPEL, Caroline LAROYE, Amir BOUFENZER, Léonore AVERCENC, Céline HUSELSTEIN
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Patent number: 10510177Abstract: A data processing device applies pattern data to surface data on the basis of projection data, subdividing the surface data into voxels and determining the optimum projection data for each voxel according to its surroundings.Type: GrantFiled: June 28, 2016Date of Patent: December 17, 2019Assignees: Inria Institute National De Recherche En Informatique Et En Automatique, Universite De LorraineInventors: Sylvain Lefebvre, Jeremie Dumas, An Lu
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Patent number: 10351945Abstract: The method for obtaining a nano-capsule structure includes at least one layer of resin deposited on a layer of substrate. The capsule nanometric in size is capable of enabling the encapsulation of a compound. The layer of resin is structured, by low voltage electron lithography, or by optical lithography or by nanoimprinting in such a way as to obtain at least one cavity in the thickness of the layer of resin. The cavity has a depth smaller than the thickness of the layer of resin. At least one layer of an encapsulating material is isotropically deposited by sputtering the material under vacuum. The cavity is sealed with a sealing material. The layer of resin is dissolved by soaking in a suitable solvent.Type: GrantFiled: June 13, 2013Date of Patent: July 16, 2019Assignees: UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Stefan McMurtry, Omar Elmazria
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Patent number: 10339698Abstract: A method for discriminating and identifying, by 3D imaging, an object in a complex scene comprises the following steps: generating a sequence of 2D MIP images of the object, from a 3D voxel volume of the complex scene, this volume visualized by an operator by using an iterative process of MIP type from a projection plane and an intensity threshold determined by the operator on each iteration, automatically extracting, from the sequence of images, coordinates of a reduced volume corresponding to the sequence of images, choosing one of the intensity thresholds used during the iterations, automatically extracting, from the 3D volume of the complex scene, from the coordinates and chosen intensity threshold, a reduced 3D volume containing the object, automatically generating, from the reduced volume, by intensity threshold optimization, an optimized intensity threshold and an optimized voxel volume, a color being associated with each intensity, identifying the object by visualization.Type: GrantFiled: December 17, 2015Date of Patent: July 2, 2019Assignees: THALES, UNIVERSITE DE LORRAINE, SISPIAInventors: Stefan Berechet, Ion Berechet, Jean-Baptiste Bellet, Gérard Berginc
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Patent number: 10316224Abstract: A composition based on phenolic resin comprising at least one phenolic resin, a vegetable protein hydrolysate, preferentially a wheat gluten hydrolysate, and an agent for accelerating curing, and also to the process for the production thereof.Type: GrantFiled: October 7, 2014Date of Patent: June 11, 2019Assignees: TEREOS STARCH AND SWEETENERS BELGIUM, UNIVERSITE DE LORRAINEInventors: Antonio Pizzi, Marie-Christine Lagel, Andreas Redl
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Patent number: 10290138Abstract: Device comprising a memory (2) storing sound data, three-dimensional surface data, and a plurality of control data sets which represent control points defined by data of coordinates which are associated with sound data, and a processor (4) which, on the basis of first and second successive sound data, and of first three-dimensional surface data, selects the control data sets associated with the first and second sound data, and defines second three-dimensional surface data by applying a displacement to each point. The displacement of a given point is calculated as the sum of displacement vectors calculated for each control point on the basis of the sum of first and second vectors, weighted by the ratio between the result of a function with two variables exhibiting a zero limit at infinity applied to the given point and to the control point and the sum of the result of this function applied to the point on the one hand and to each of the control points on the other hand.Type: GrantFiled: March 10, 2016Date of Patent: May 14, 2019Assignee: UNIVERSITE DE LORRAINEInventors: Slim Ouni, Guillaume Gris
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Patent number: 10227684Abstract: Process for depositing a coating on a substrate having at least one cavity, comprising a step of mixing ground powders of an activating agent and a powder of the metal or of the alloy to be deposited on the substrate that were ground in step a) and a liquid so as to form a suspension, and a step of applying the suspension to the portion of the substrate to be coated.Type: GrantFiled: February 4, 2014Date of Patent: March 12, 2019Assignees: L'Air Liquide Societe Anonyme Pour L'Etude Et L'Exploitation Des Procedes Georges Claude, Centre National De La Recherche Scientifique, Universite De LorraineInventors: Nicolas Richet, Thierry Mazet, Michel Vilasi, Stephane Mathieu
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Patent number: 10211618Abstract: A method and a circuit for detecting an electric arc in an electric circuit supplied with AC current during a supply period includes measuring at least one input signal (S) among a current (I) and an input voltage (U) of the electric circuit, supplying a warning signal (A1) to indicate that an electric arc occurs when the input signal (S) is constant over at least one portion of the supply period, digitally sampling the input signal (S) during the measurement thereof according to predetermined levels and, to identify that the input signal (S) is constant, determining the frequency at which each level is reached by the input signal (S) over a predetermined time window, comparing the frequency of each level with a predetermined warning threshold, and issuing the warning signal if the frequency of at least one of the levels is higher than the warning threshold.Type: GrantFiled: February 3, 2015Date of Patent: February 19, 2019Assignees: LEACH INTERNATIONAL EUROPE SA, UNIVERSITE DE LORRAINEInventors: Jonathan Andrea, Patrick Schweitzer, Serge Weber, Etienne Tisserand, Marc Bournat
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Patent number: 10167468Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of cardiovascular fibrosis. In particular, the present invention relates to an inhibitor of Neutrophil Gelatinase-Associated Lipocalin (NGAL) activity or expression for use in a method for treating or preventing cardiovascular fibrosis in a subject in need thereof.Type: GrantFiled: January 31, 2017Date of Patent: January 1, 2019Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITE DE LORRAINE, CENTRE HOSPITALIER ET UNIVERSITAIRE DE NANCY (CHU), UNIVERSITE PARIS DIDEROT-PARIS 7, UNIVERSITE PARIS DESCARTESInventors: Frederic Jaisser, Nicolette Farman, Antoine Tarjus, Patrick Rossignol, Faiez Zannad