Patents Assigned to Universite des Sciences et Technologies de Lille
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Patent number: 10266474Abstract: The present invention relates to the use of molybdenum and vanadium mixed oxides, optionally iron doped, as catalysts for the oxidation of unsaturated alcohols, in particular allyl alcohol, and also to a process for the production of unsaturated carboxylic acids, in particular acrylic acid, in the gas phase, in the presence of such a catalyst.Type: GrantFiled: June 18, 2015Date of Patent: April 23, 2019Assignees: Centre National De La Recherche Scientifique, Universite Des Sciences et Technologies De Lille 1, Hokkaido University, Ecole Centrale De LilleInventors: Sébastien Paul, Benjamin Katryniok, Franck Dumeignil, Marcia Araque Marin, Toru Murayama, Wataru Ueda
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Patent number: 10252909Abstract: The present invention relates to a method for dry reforming of at least one alkane carried out in at least one reaction chamber, preferably with a catalytic bed, having a stream of gas passing through same. According to the invention, said at least one reaction chamber comprises a catalytic solid which is cyclically and alternatively exposed to a stream of at least one alkane and a stream containing carbon dioxide, such that said catalytic solid is used as an oxidation vector.Type: GrantFiled: April 27, 2015Date of Patent: April 9, 2019Assignees: Universite Des Sciences et Technologies De Lille 1, Centre National De La Recherche Scientifique (C.N.R.S.)Inventors: Axel Lofberg, Louise Duhamel Jalowiecki, Jesus Guerrero
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Publication number: 20170258871Abstract: The invention relates to an EphA2 inhibitor for the use thereof in the treatment of solid cancer treated with a TrkA inhibitor, and a TrkA inhibitor for the use thereof in the treatment of solid cancer treated with an EpbA2 inhibitor. The invention also relates to a method for the prognosis of survival of a patient who has a solid cancer, comprising a step of detecting the expression of TrkA and EphA2 in a biological sample of the patient, the co-expression of TrkA and EphA2 being associated with a poor prognosis of survival of the patient.Type: ApplicationFiled: September 7, 2015Publication date: September 14, 2017Applicants: UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)Inventors: Robert Toillon, Xuefen Le Bourhis, Cyril Corbet, Leo Aubert, Matthieu Guilbert
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Patent number: 9745243Abstract: A method for oxidation of glycerol into glyceric acid is described, which includes a step of treating glycerol with a supported metal catalyst in the presence of oxygen, said catalyst including platinum and a metal element selected from the group comprising tin, molybdenum, bismuth and a mixture thereof.Type: GrantFiled: October 14, 2014Date of Patent: August 29, 2017Assignees: PIVERT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE 1Inventors: Mickaeel Capron, Franck Dumeignil, Elzbieta Skrzynska
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Patent number: 9701615Abstract: A method for synthesising a second ester from a first ester, the method including the following steps: a) placing a first ester and a catalyst in the presence of dihydrogen such as to obtain a first alcohol and a second alcohol; b) extracting the second alcohol from the reaction medium; c) reacting the first alcohol with the catalyst of step a) in order to obtain a second ester and dihydrogen; and d) recirculating the dihydrogen obtained in step c) by injecting same into step a).Type: GrantFiled: November 6, 2014Date of Patent: July 11, 2017Assignees: PIVERT, Centre National de la Recherche Scientifique (CNRS, UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE 1, ECOLE CENTRALE DE LILLEInventors: Franck Dumeignil, Simon Desset, Sébastien Paul, Guillaume Raffa, Lei Zhang
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Patent number: 9550715Abstract: The invention relates to a method for synthesizing glycolic acid or one of the salts thereof, including the following step: placing glycerol and an oxidizing agent in contact with one another in a reaction medium in the presence of a silver-based catalyst on a substrate, said substrate including a material selected from the group consisting of CeO2, basic Al2O3 optionally doped with a calcium or cerium oxide, an amphoteric resin, ZrO2, and a mixture of said materials. The invention also relates to the use of a silver-based catalyst on a substrate that can be used in said method.Type: GrantFiled: May 26, 2014Date of Patent: January 24, 2017Assignees: PIVERT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE 1Inventors: Elzbieta Skrzynska, Franck Dumeignil, Mickaël Capron, Louise Duhamel
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Patent number: 9548413Abstract: A device for switching an electrical signal, controlled by an optical wave and having an on state and an off state, which can be inserted into a microwave transmission line, comprises a semiconductor substrate on which two conductive tracks are formed, these tracks being separated by a gap providing electrical insulation between the two tracks and each being connected to an input port and an output port, in the on state the electrical contact between the two tracks being established by illuminating the substrate in the region of the gap by means of the optical wave, the input impedance and the output impedance of said switching device being mismatched to the impedance of the transmission line in the off state and are matched to the impedance of the transmission line in the on state.Type: GrantFiled: December 20, 2013Date of Patent: January 17, 2017Assignees: THALES, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE SAIC, UNIVERSITE PARIS 6 PIERRE ET MARIE CURIEInventors: Charlotte Tripon-Canseliet, Jean Chazelas, Didier Decoster
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Patent number: 9476827Abstract: The invention substantially relates to an imaging system for the chemical, biological or biochemical analysis of a sample (10), comprising a device (40) for holding the sample (10), a device (20) for optical detection, a lighting device (30), liable to emit a monochromatic light beam, and a wide aperture objective (f1), It is substantially characterized in that the objective (f1) is configured for, downstream of the sample (10): focusing the excitation light beam reflected at a point (C) located in the focal plane (FF) of said objective (f1), and transforming the retransmitted or scattered light beam into a quasi-parallel beam, and in that the system further comprises a device (70) for selectively blocking the collected light beam by said objective (f1).Type: GrantFiled: December 7, 2011Date of Patent: October 25, 2016Assignees: Ecole Polytechnique, Centre National De La Recherche Scientifique-CNRS, Universite Des Sciences Et Technologies De Lille 1Inventors: François Ozanam, Jean-Noël Chazalviel, Rabah Boukherroub, Elisabeth Anne-Gabrielle Galopin, Anne Chantal Gouget-Laemmel, Sabine Szunerits, Larbi Touahir
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Publication number: 20160130209Abstract: The invention relates to a method for synthesising glycolic acid or one of the salts thereof, including the following step: placing glycerol and an oxidising agent in contact with one another in a reaction medium in the presence of a silver-based catalyst on a substrate, said substrate including a material selected from the group consisting of CeO2, basic Al2O3 optionally doped with a calcium or cerium oxide, an amphoteric resin, ZrO2, and a mixture of said materials. The invention also relates to the use of a silver-based catalyst on a substrate that can be used in said method.Type: ApplicationFiled: May 26, 2014Publication date: May 12, 2016Applicants: PIVERT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE 1Inventors: Elzbieta SKRZYNSKA, Franck DUMEIGNIL, Mickaël CAPRON, Louise DUHAMEL
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Patent number: 9061045Abstract: A ProNGF inhibitor for preparing a drug, said drug being in particular useful for blocking remote dissemination and cell invasion in patients suffering from cancer, in particular breast, thyroid or lung cancer.Type: GrantFiled: June 26, 2012Date of Patent: June 23, 2015Assignees: BIOMERIEUX, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLEInventors: Geneviève Choquet-Kastylevsky, Yohann Demont, Hubert Hondermarck
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Patent number: 8962487Abstract: The present invention relates to a process for fabricating microchannels on a substrate and to a substrate comprising these microchannels, the invention being especially applicable to the fabrication of microstructured substrates for microelectronic, microfluidic and/or micromechanical systems. The process includes a step (a) of producing at least one or at least two patterns 2 on the surface of a bottom layer 1 and a step (b) of depositing, on top of the bottom layer and the pattern or patterns, a layer 3 of polymer material obtained by polymerizing an organic or organometallic monomer that contains siloxane functional groups, for example tetramethyldisiloxane, in a plasma-enhanced, optionally remote plasma-enhanced, chemical vapor deposition reactor (PECVD or optionally RPECVD) reactor.Type: GrantFiled: February 24, 2010Date of Patent: February 24, 2015Assignee: Universite des Sciences et Technologies de LilleInventors: Abdennour Abbas, Didier Guillochon, Bertrand Bocquet, Philippe Supiot
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Patent number: 8906403Abstract: A method for preparing a biomaterial containing at least one bioactive molecule from a base biomaterial, comprising the following successive operations carried out on the base biomaterial: a) application of a solid mixture of: cyclodextrin(s) and/or cyclodextrin derivative(s) and/or cyclodextrin inclusion complex(es) and/or cyclodextrin derivative inclusion complex(es), at least one poly(carboxylic) acid, and optionally a catalyst; b) heating at a temperature between 100° C. and 200° C. for a period of 1 to 60 minutes; c) washing with water; d) drying, wherein at least one bioactive agent is incorporated in the biomaterial by impregnation of the biomaterial after the drying step in a concentrated solution of the bioactive agent.Type: GrantFiled: November 15, 2005Date of Patent: December 9, 2014Assignees: Universite des Sciences et Technologies de Lille SAIC, Universite de Droit et SanteInventors: Bernard Martel, Nicolas Blanchemain, François Boschin, Stephan Haulon, Elisabeth Delcourt Debruyne, Michel Morcellet, Hartmut Friederich Hildebrand
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Patent number: 8770038Abstract: The invention relates to a cell for testing geomaterials on cylindrical specimens, of rock, ground or materials manufactured on sampling sites, including at least one piston for subjecting a specimen to a stress directed along the longitudinal axis of the specimen. According to the invention, the cell has, in addition, means for shearing the specimen, capable of cracking the specimen while it is being compressed in said at least one piston.Type: GrantFiled: July 7, 2009Date of Patent: July 8, 2014Assignee: Universite des Sciences et Technologies de LilleInventor: Jean Secq
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Patent number: 8763160Abstract: During a measurement in KFM mode of the surface potential of a material (P), a detection point (1) is arranged above a surface (S) of the material. Two piezoelectric actuators (2, 5) are used to monitor a mean distance of the detection point relative to the surface of the material and a mechanical oscillation of said point. During the measurement, a control voltage is applied between control electrodes (2a, 2b) of the piezoelectric actuator (2) which is dedicated to the mechanical oscillation of the detection point (1), said control voltage not having an alternative component to an angular frequency of electrical energization of said detection point. A result of the KFM measurement is therefore separate from operating parameters such as a projection angle used to perform closed-loop control and a value of the angular frequency of electrical energization. The invention thus provides absolute measurements of surface potentials.Type: GrantFiled: February 9, 2011Date of Patent: June 24, 2014Assignees: Centre National de la Recherche Scientifique—CNRS, Universite des Sciences et Technologies de LilleInventors: Thierry Melin, Didier Theron, Sophie Barbet, Dominique Deresmes, Heinrich Diesinger
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Patent number: 8652514Abstract: Novel peptides having antimicrobial activity, and compositions containing the same.Type: GrantFiled: December 13, 2010Date of Patent: February 18, 2014Assignees: Centre National de la Recherche Scientifique, Universite des Sciences et Technologies de LilleInventors: Aurélle Tasiemski, Michel Salzet, Françoise Gaill
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Publication number: 20130314528Abstract: The invention substantially relates to an imaging system for the chemical, biological or biochemical analysis of a sample (10), comprising a device (40) for holding the sample (10), a device (20) for optical detection, a lighting device (30), liable to emit a monochromatic light beam, and a wide aperture objective (f1), It is substantially characterized in that the objective (f1) is configured for, downstream of the sample (10): focusing the excitation light beam reflected at a point (C) located in the focal plane (FF) of said objective (f1), and transforming the retransmitted or scattered light beam into a quasi-parallel beam, and in that the system further comprises a device (70) for selectively blocking the collected light beam by said objective (f1).Type: ApplicationFiled: December 7, 2011Publication date: November 28, 2013Applicants: ECOLE POLYTECHNIQUE, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRSInventors: François Ozanam, Jean-Noël Chazalviel, Rabah Boukherroub, Elisabeth Anne-Gabrielle Galopin, Anne Chantal Gouget Laemmel, Sabine Szunerits, Larbi Touahir
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Patent number: 8563620Abstract: The process for the synthesis of a silica monolith comprises the following steps: hydrolysis of a silicon alkoxide in order to form a hydrolysis precursor followed by a condensation of said hydrolysis precursor in the presence of an organic solvent, in the presence of water and of a basic catalyst in order to form oligomeric clusters containing several silicon atoms; dispersion of said oligomeric clusters in a solution in order to form a sol; polymerization of the sol in order to obtain a gel via a first heat treatment, at a temperature below the boiling point of the constituents of the sol; drying of the gel via a second heat treatment; conversion of the gel to a xerogel via a third heat treatment; dehydration and densification of the xerogel until the silica monolith is obtained via a fourth heat treatment.Type: GrantFiled: October 1, 2009Date of Patent: October 22, 2013Assignees: Universite des Sciences et Technologies de Lille, Centre National de la Recherche Scientifique (CNRS)Inventors: Mohamed Bouazaoui, Bruno Capoen, Hicham El-Hamzaoui, Laurent Bigot, Géraud Bouwmans
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Patent number: 8561474Abstract: The invention relates to a triaxial cell for testing geomaterials on specimens. The triaxial cell has at least one piston for subjecting a specimen to stress directed along the longitudinal axis of the specimen. Hydraulic means are provided for subjecting the lateral wall of the specimen to a stress, under the pressure of a fluid. The cell has at least one sealed test chamber-in which the specimen is placed, and a circuit for the controlled pressurization of said test chamber with a fluid, called the pressurizing fluid, and for the controlled draining of said fluid therefrom. The cell has mechanisms for subjecting the specimen to a tensile force, which are configured for removably fastening it between two attachments intended to move apart or closer together under the action of the piston so as to subject said specimen to longitudinal stress or on the contrary to remove the load therefrom.Type: GrantFiled: July 7, 2009Date of Patent: October 22, 2013Assignee: Universite des Sciences et Technologies de LilleInventor: Jean Secq
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Publication number: 20130171173Abstract: A ProNGF inhibitor for preparing a drug, said drug being in particular useful for blocking remote dissemination and cell invasion in patients suffering from cancer, in particular breast, thyroid or lung cancer.Type: ApplicationFiled: June 26, 2012Publication date: July 4, 2013Applicants: UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE, BIOMERIEUXInventors: Geneviève CHOQUET-KASTYLEVSKY, Yohann DEMONT, Hubert HONDERMARCK
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Patent number: 8442372Abstract: The microstructured optical fibre comprises a core (4) surrounded by a sheath (1) comprising a base material having a refraction index (ni) and a plurality of at least two different types of inclusion: a first type of inclusion (2) having a refraction index n2 (n2>n1), and a second type of inclusion (3) having a refraction index n3 (n3<n1). The inclusions (2, 3) are arranged and dimensioned in such a way as to ensure guidance, by total internal reflection (RTI), of a fundamental mode of the light, centred on a wavelength ?RTI, and of a fundamental mode of the light in the first photonic forbidden band (BG1), centred on a wavelength ?BG1, which is different to that ?RTI of the fundamental mode guided by total internal reflection (RTI).Type: GrantFiled: July 25, 2008Date of Patent: May 14, 2013Assignee: Universite des Sciences et Technologies de LilleInventors: Yves Quiquempois, Geraud Bouwmans, Mathias Perrin, Aurelie Betourne, Marc Douay, Karen Delplace, Antoine Le Rouge, Laurent Bigot