Patents Assigned to Universite Joseph Fourier (Grenoble 1)
  • Patent number: 10210995
    Abstract: A method for producing a film including a non-magnetic matrix and a plurality of three-dimensional magnetic microstructures arranged within the matrix according to a predetermined pattern. The method includes providing a master substrate with a magnetically structured face formed from a plurality of magnetic field micro-sources, having a magnetic field gradient of between 102 and 106 T/m. The method also includes adding magnetic microparticles or nanoparticles to the magnetically structured face of the master substrate, the particles agglomerating into three-dimensional microstructures arranged under an effect of an attractive magnetophoretic force exerted by the magnetic field gradient on the surface of the master substrate. The method further includes depositing, on the magnetically structured face of the master substrate, a matrix made from a non-magnetic material, in such a way as to enclose the arranged microstructures and to form the film and peeling the film from the master substrate.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: February 19, 2019
    Assignees: Centre National de la Recherche Scientifique, Universite Joseph Fourier-Grenoble 1
    Inventors: Nora Dempsey, Frédéric Dumas-Bouchiat, Luiz Fernando Zanini, Dominique Givord
  • Patent number: 9816123
    Abstract: The present invention relates to a method for producing a molecule of interest in bacteria which is based on a reversible growth arrest of the bacteria at the cellular growth global control system level, thus allowing an improved yield of production of said molecule of interest.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: November 14, 2017
    Assignees: Inria Institut National De Racherche En Informatiq, Universite Joseph Fourier-Grenoble 1
    Inventors: Johannes Geiselmann, Hidde De Jong, Delphine Ropers, Jérôme Izard
  • Patent number: 9493761
    Abstract: The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor.
    Type: Grant
    Filed: February 29, 2012
    Date of Patent: November 15, 2016
    Assignees: UNIVERSITE JOSEPH FOURIER (GRENOBLE 1), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Benoit Polack, Aline Thomas
  • Publication number: 20160159937
    Abstract: The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions.
    Type: Application
    Filed: February 12, 2016
    Publication date: June 9, 2016
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ( CNRS), UNIVERSITE JOSEPH FOURIER - GRENOBLE 1
    Inventors: Rachel AUZELY, Jimmy MERGY, Eric BAYMA-PECIT
  • Publication number: 20160007952
    Abstract: An image processing method enables an elasticity image of a body including a cavity to be produced on the basis of the material(s) forming the body, wherein the method includes the steps of: receiving a deformation image illustrating a field of movement of the points of the body on the basis of a pressure difference in the body, estimating a shape function of the body from the deformation image, calculating an elasticity image of the body on the basis of the shape function, of the pressure difference and of the deformation image.
    Type: Application
    Filed: February 17, 2014
    Publication date: January 14, 2016
    Applicant: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1
    Inventors: Jacques OHAYON, Flavien DELEAVAL, Guy CLOUTIER
  • Patent number: 9213325
    Abstract: A system is provided for managing services in a living place, including: a supervision system, an anticipative solving system, the anticipative solving system including a processing and memory system for: storing service type problem generators and powers and occupants' satisfaction-related transversal problem generator; collecting service type and related parameters for each service; generating instantiated constraint data for each service according to its type and an anticipative service type problem data based on the constraint data; generating global anticipative problem data; computing set-point data for each service based on the solved global anticipative problem; sending set-point data to the supervision system; and a reactive system adapted to adjust the set-point data computed by the anticipative system depending on the current state of each service.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: December 15, 2015
    Assignees: INSTITUT POLYTECHNIQUE DE GRENOBLE, UNIVERSITE JOSEPH FOURIER - GRENOBLE 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Stéphane Ploix, Duy Long Ha, Shadi Abras, Mireille Jacomino, Frédéric Wurtz, Seddik Bacha
  • Publication number: 20150289755
    Abstract: The invention concerns a multi-view imaging system for laparoscopic surgery comprising: A tubular member; A first imaging device having a longitudinal body and an active end for acquiring images, intended to be inserted through the tubular member, and movable in the tubular member in translation along the longitudinal axis and/or in rotation about the longitudinal axis; A second imaging device comprising at least two cameras each mounted on a support member and movable relative to the tubular member between: a stowed position in which the cameras are positioned inside the tubular member, and a deployed position in which the cameras are positioned outside the tubular member at the distal end, the cameras being arranged on either side of the longitudinal axis of the tubular member and being held secure relative to the tubular member by holding means, so as to follow any movement of the tubular member.
    Type: Application
    Filed: October 4, 2013
    Publication date: October 15, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE JOSEPH FOURIER - GRENOBLE 1, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE
    Inventors: Sandrine VOROS, Philippe CINQUIN, Céline FOUARD, Brahim TAMADAZTE
  • Publication number: 20150293090
    Abstract: The present disclosure relates to a method for identifying the presence or absence of anti-Toxoplasma gondii antibodies in a human or animal serum, including placing the previously drawn serum in contact with antigens capable of binding with the anti-Toxoplasma gondii antibodies, and the observation of a bond or of an absence of a bond of antibodies with the antigens, and a combination of two recombinant GRA2 and GRA6 proteins. In particular, the antigens are attached to a support, in particular an ELISA plate. This test is preferably carried out as a supplement to another test for diagnosing toxoplasmosis.
    Type: Application
    Filed: October 16, 2013
    Publication date: October 15, 2015
    Applicants: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE
    Inventors: Corinne Mercier, Marie-France Delauw, Hervé Pelloux, Hélène Fricker-Hidalgo
  • Publication number: 20150283247
    Abstract: Polymer composition comprising a mixture of PBA modified HA polymer grafted on at least a hydroxyl with a group comprising phenylboronic acid and Cis-diol modified HA polymer grafted on at least a hydroxyl with a group comprising a cis-diol. Injectable or implantable glucose-sensitive hydrogels comprising a this polymer composition.
    Type: Application
    Filed: November 6, 2013
    Publication date: October 8, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE JOSEPH FOURIER - GRENOBLE 1
    Inventors: Rachel Auzely-Velty, Emilie Hachet, Bogdan Catargi, Valérie Ravaine, Léa Messager
  • Patent number: 9133237
    Abstract: The present invention relates to a method for preparing a cyclic peptide with antiparasite activity and anticancer activity. The invention also relates to this peptide as an antiparasite agent, for example in the treatment of toxoplasmosis and as an anticancer agent. The invention also relates to the use of this cyclic peptide for treating organs ex vivo before transplantation.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: September 15, 2015
    Assignees: UNIVERSITE JOSEPH FOURIER (GRENOBLE 1), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, (INSERM) INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Yung-Sing Wong, Mohamed-Ali Hakimi, Alexandre Bougdour, Hervé Pelloux, Danièle Maubon
  • Patent number: 9089499
    Abstract: The invention relates to the use of para-coumaric acid or para-hydroxycinnamic acid derivatives in cosmetic or dermatological compositions, specifically to the use of at least one compound derived from para-coumaric acid having a general formula (I) below: in which, especially, Z represents an oxygen or an —NH— group; X and Y are identical and each represent a CH or CH2 group, as an active principle with depigmenting, free-radical-scavenging and/or antiinflammatory activity. The invention also relates to the use of the above compounds for cosmetic care or for the preparation of a pharmaceutical composition, especially for depigmenting an area of skin, having antiradical and/or antiinflammatory activity.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: July 28, 2015
    Assignees: Universite Joseph Fourier-Grenoble 1, BASF Beauty Care Solutions France S.A.S.
    Inventors: Sabrina Okombi, Delphine Rival, Ahcene Boumendjel, Anne-Marie Mariotte, Eric Perrier
  • Publication number: 20150173167
    Abstract: The disclosure includes a coaxial microwave applicator for plasma production, including a coaxial tube formed by a central core and an outer conductor separated from the central core by an annular space allowing propagation of microwaves. The applicator includes: a cylindrical permanent magnet disposed at the end of the central core; and at least one annular permanent magnet disposed at the end of the outer conductor, all of the magnets disposed at the end of the coaxial tube having the same direction of magnetisation. The magnetisation of the magnets forms a magnetic field suitable for generating, in a zone away from the end of the applicator, an electronic cyclotronic resonance coupling with the electric microwave field of the applicator. The external radius and the magnetisation of the annular magnet are selected such that the magnetic field lines generated by the magnets pass through the coupling zone in a direction substantially parallel to the axis of the applicator.
    Type: Application
    Filed: July 10, 2013
    Publication date: June 18, 2015
    Applicant: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1
    Inventors: Ana Lacoste, Jacques Pelletier
  • Publication number: 20150137682
    Abstract: The disclosure includes a glow-discharge lamp including: an elongate casing transparent to illuminating radiation and containing a plasma gas; a device for applying an electric field for maintaining a plasma in the so-called positive column region of the casing, the device including two electrodes forming an anode and a cathode located in the casing at each end thereof; and a radio-frequency or microwave cathode plasma source arranged in the casing in relation to the cathode-forming electrode, such as to generate a high-frequency discharge located on the surface of the electrode in order to generate the plasma. The disclosure also includes a lighting method of such a glow-discharge lamp.
    Type: Application
    Filed: July 10, 2013
    Publication date: May 21, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE JOSEPH FOURIER-GRENOBLE 1
    Inventors: Ana Lacoste, Jacques Pelletier
  • Publication number: 20150126880
    Abstract: A method is disclosed for continuously monitoring a blood pressure measurement using a sensor connected by a hydraulic link to an arterial catheter, the method includes determining the dynamic parameters of the link, analyzing the frequency content of the incident signal, detecting one of the following situations: (a) ability of the link to transmit the incident signal with a distortion below a threshold, (b) ability of the link to transmit the incident signal with a distortion above the threshold and possibility of correcting the measured signal, (c) inability of the link to transmit the incident signal with a distortion below the threshold and impossibility of correcting the measured signal, periodic application of a mechanical action to the tubing providing the hydraulic link.
    Type: Application
    Filed: December 21, 2012
    Publication date: May 7, 2015
    Applicants: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1, AUTOMATISME ET INFORMATIQUE INDUSTRIELLE
    Inventors: Francis Grimbert, Yves Lavault
  • Publication number: 20150044201
    Abstract: The present disclosure concerns a method for the identification of the presence or absence of cancer cells in a biological sample, more particularly a method for the identification of the susceptibility or resistance to a treatment with CD20 agonists of cancer cells in a biological sample, the methods including determining the level of expression of the gene Cyclon in the cells and comparing the level of expression to the level of expression in a non-cancer cell, wherein a level of expression higher than the level of expression in a non-cancer cell is an indication of the presence of a cancer cell, more particularly an indication of cancer cells with a resistance to treatment with antagonists. Kits for the determination of a level of expression of the Cyclon gene in a biological sample, a method for the identification of Cyclon expression antagonists, and methods for treating patients are provided.
    Type: Application
    Filed: January 10, 2013
    Publication date: February 12, 2015
    Applicants: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE, UNIVERSITE JOSEPH FOURIER - GRENOBLE 1, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE
    Inventors: Mary Callanan, Anouk Emadali, Myriam Ferro, Saadi Khochbin, Sophie Pison-Rousseaux
  • Publication number: 20140335125
    Abstract: A process for obtaining an adapted strain of Pseudomonas includes the following steps: deleting the genes ExoS, ExoT, aroA and IasI in an initial Pseudomonas strain cultivated in a LB medium; progressively cultivating this strain in a chemically defined medium based on a glucose minimal medium supplemented with magnesium and calcium; wherein the adapted strain presents the same toxicity and secretion capacities than the initial strain, and its doubling time when cultivated in the chemically defined medium is less than 60 minutes. An adapted strain is furthermore treated to become ‘killed but metabolically active’.
    Type: Application
    Filed: December 12, 2012
    Publication date: November 13, 2014
    Applicants: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE
    Inventors: Audrey Le Gouellec, Bertrand Toussaint, Benoît Polack
  • Publication number: 20140315232
    Abstract: The present invention relates to a method for dosing the control capacity of plasma serpin (SERine Protease INhibitor) C1 inhibitor (C1Inh) on the basis of a patient blood sample. The invention also relates to a kit specially designed for said dosing.
    Type: Application
    Filed: November 28, 2012
    Publication date: October 23, 2014
    Applicant: Universite Joseph Fourier (Grenoble 1)
    Inventors: Christian Drouet, Arije Ghannam, Federica Defendi, Bertrand Favier
  • Publication number: 20140255303
    Abstract: The present invention relates to nanobodies specifically directed against VCAM-1 and to their use in medical imaging and in diagnostic, prognostic and treatment methods.
    Type: Application
    Filed: August 22, 2012
    Publication date: September 11, 2014
    Applicant: UNIVERSITE JOSEPH FOURIER- GRENOBLE 1
    Inventors: Catherine Ghezzi, Daniel Fagret, Alexis Broisat, Nick Devoogdt, Tony Lahoutte, Serge Muydermans
  • Publication number: 20140226959
    Abstract: The invention concerns a device for heating an object (6) in an intense magnetic field, comprising:—a light source (1), an optic fibre (2) for transporting the light emitted by said light source (1) and emitting a beam of light in the direction of the object (6) to be heated, a converging optical system (3), a diaphragm (4) positioned at the focusing point of the optical system (3),—a reflector (5), whereof the inner wall is defined by the revolution of a semi-parabola around an axis perpendicular to the optical axis of the parabola and passing through the focal point of said parabola, the optical axis of said reflector (5) coinciding with the optical axis (A) of the optical system (3) and the focal point (F?) of said reflector coinciding with the focusing point of said optical system (3).
    Type: Application
    Filed: September 20, 2012
    Publication date: August 14, 2014
    Applicant: UNIVERSITE JOSEPH FOURIER - GRENOBLE 1
    Inventors: Pierre-Frederic Sibeud, Eric Beaugnon, Gilles Pont
  • Publication number: 20140051099
    Abstract: The present patent application relates to a method for diagnosing angioedema with a gain-of-function mutation of kinin formation, and for determining the amount of BK or des-Arg9 -BK antagonist required for halting the effects of angioedema, from a plasma sample of a patient. The invention also relates to a kit for said determination.
    Type: Application
    Filed: April 12, 2012
    Publication date: February 20, 2014
    Applicants: CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE, UNIVERSITE JOSEPH FOURIER (GRENOBLE 1)
    Inventors: Christian Drouet, Samuel Luyasu, Arije Ghannam