Abstract: The present disclosure relates to a device for positioning and/or orienting, in the body of a patient, a surgical tool carried by a tool-holder, including a platform capable of being placed on the body of the patient, an orientable carrier, at least one part of which is rigidly connected to the tool-holder, means for guiding the orientable carrier rotationally relative to the platform in two directions of a plane parallel to the platform, at least 2 pneumatic actuators which engage with the orientable carrier such that a variation in pressure of at least one of the pneumatic actuators causes the orientable carrier to rotate in the first direction and/or the second direction, in which the pneumatic actuators are volumes that can deform in a predetermined direction as a function of the internal pressure.

Abstract: The invention relates to an endoscopic imaging system for observation of an operative site (2) inside a volume (1) located inside the body of an animal, comprising: Image capture means (3) intended to provide data on the operative site (2), Processing means (4) to process data derived from the image capture means, Display means (5) displaying data processed by the processing means (4), characterized in that: The image capture means (3) comprise at least two image capture devices that are independent and mobile relative to one another, the image capture devices being intended to be positioned inside the volume (1), and in that: The processing means (4) comprise computing means to obtain three-dimensional data on the observed operative site (2) from data provided by the image capture devices, and means to reconstruct a three-dimensional image of a region of interest of the operative site from the three-dimensional data obtained.

Abstract: The invention concerns a device to prevent urinary leakage intended to be implanted in a patient, comprising: compression means (1, 3, 4, 5) to compress the patient's urethra, electronic control means (2) to actuate the compression means (1, 3, 4, 5), characterized in that it further comprises measurement means (7) to measure the patient's activity, coupled with the control means (2), the control means (2) functioning according to a predictive model of urinary leakage based on patient activity, so as to anticipate a possible urinary leak in relation to the measured activity of the patient.

Abstract: The invention relates biosensor comprising a conductive or semi-conductive support and an intercalator polymer, wherein the intercalator polymer comprises monomer units of formula (I) wherein P is an electropolymerizable moiety selected among the group consisting in pyrrole, acetylene, phenol, aniline, thiophene, carbazole and azulene; Sp is a spacer, and Im is an intercalator. The invention also relates to a method for the detection of a DNA sequence with the biosensor, comprising the steps of: hybridizing the DNA sequence with a DNA probe for forming a dsDNA incubating the biosensor with the dsDNA for anchoring the dsDNA to the intercalator detecting the quantity of dsDNA on the biosensor.

Abstract: The invention relates to a method for analysing a surgical operation by endoscopy in an operation field in a space inside the body of an animal, characterised in that it comprises the steps of: detecting at least one tool (1, 2, 3) present in the operation field; detecting at least one portion of an organ (4) in the vicinity of the detected tool (1, 2, 3); determining the position of the detected tool (1, 2, 3) relative to the detected organ (4) so that the detected tool (1, 2, 3), the detected portion of the organ (4) and their relative positioning form parameters defining a detected operation field; selecting, in a database, a conceptual field of operation corresponding to the detected operation field based on the detected tool (1, 2, 3), the detected portion of the organ (4), and their relative positioning; comparing the parameters of the detected field of operation with the parameters defining the selected conceptual field of operation in order to determine the deviations between said parameters; providin

Abstract: The present invention relates to a tactile stimulation device of an individual, comprising at least three stimulators distributed throughout the buccal cavity, in contact with the gums, the inside of the cheeks and/or the lips so as to communicate three-dimensional information to the individual.

Abstract: The invention relates to a device comprising a casing and a biomimetic artificial membrane arranged within the casing to form two distinct chambers, wherein each chamber is provided for enclosing a liquid of a given composition, and wherein the biomimetic artificial membrane comprises a semi-permeable membrane for supporting a lipid membrane, the lipid membrane comprising a plurality of lipid molecules arranged in a layer and including at least a transport protein, the transport protein being adapted for transport of ions and/or molecules of the liquids between the two chambers.

Abstract: The present invention relates to a new hydrogel functionalized with a polymerizable moiety, the polymerized hydrogels, films and gels comprising the same and their use for cells, proteins, DNA or other molecules encapsulation, including use as biosensors or bioreactors.

Abstract: The invention relates to a pharmaceutical composition containing as an active ingredient at least one compound selected from the compounds of the formula (II), in which the S atom is bonded to the nucleoside carbon at T or to the nucleoside carbon at 3?, and from the compounds of the following formula (III): formulae in which B is a nucleotide natural or modified base, x is 0, 1 or 2, and R1 and R represent a carbonated group or a molecular hydrocarbon remnant that can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si, X where X is halogen. The invention also relates to pharmaceutically acceptable carrier.

Abstract: Process for preparing a compound of the formula (I) R1-S(O)x—S(O)yR2 in which R1 represents a molecular hydrocarbon radical which can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si and X, where X represents a halogen; R2, independently of R1, represents a carbon-containing group or a molecular hydrocarbon radical which can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si and X, where X represents a halogen, and x and y are selected from 0 and 1 in such a way that the sum of x and y is not more than 1, characterized in that a compound of formula (II) R1-S(O)x—R3-Si(R4)(R5)(R6) in which R3 represents a hydrocarbon chain of two carbon atoms, which is optionally unsaturated and/or substituted, and R4, R5 and R6, which are identical or different, each represent, independently of one another, a

Abstract: The present invention relates to a new hydrogel functionalized with a polymerizable moiety, the polymerized hydrogels, films and gels comprising the same and their use for cells, proteins, DNA or other molecules encapsulation, including use as biosensors or bioreactors.

Abstract: at least one aurone or a natural or synthetic derivative of aurone, or an analogue of aurone, in which the independent phenyl ring can be substituted by a heterocycle of pyrrole, imidazole, triazole, pyridine, furan, or thiophene type, is disclosed as a cosmetic agent, or as an active substance, for the manufacture either of a cosmetic composition, or of a pharmaceutical composition, notably a dermatological composition, having a melanogenesis-inhibiting activity or a depigmenting activity, or an anti-tyrosinase activity.

Abstract: The invention concerns a method for in vitro propagation of the agent responsible for transmissible spongiform encephalopathies, or prion, comprising steps which consist in: providing a culture or a glial cell line and in infecting the culture or line with the agent responsible for transmissible spongiform encephalopathies or prion. Said method enables to obtain infected cell line capable of being used to assess the efficacy of a molecule in the reduction or inhibition of the infectiosity of the prion or for detecting the prion.

Abstract: The present invention relates to a process for in vitro culture of cells infected by a virus associated with multiple sclerosis and to the infected cell lines thus produced. According to the invention, the process includes: a) cultivation of human cells infected by a viral strain to obtain at least one culture of primary cells infected by the viral strain, b) cultivation of non-infected human cells permissive to the viral strain to obtain at least one permissive culture, c) cocultivation of at least one sample of a culture of infected primary cells and one sample of the permissive culture to obtain a first infected derived culture, d) cultivation in series of the first infected derived culture. The invention is used in particular in the pharmaceutical diagnostics industry sector.