Patents Assigned to Universite Pierre Et Marie Curie (UPMC)
  • Method of predicting survival time in myocardial infarction patients by measuring BAFF levels
    Patent number: 9688767
    Abstract: The present invention relates to a method for predicting the survival time of a patient suffering from myocardial infarction or the recurrence of a myocardial infarction. The method comprises the steps of i) determining the expression level of BAFF in a sample from the patient, ii) comparing the expression level with a predetermined reference value and iii) providing a good prognosis of the survival time or a low risk of the recurrence of a myocardial infarction when the expression level is lower than the predetermined reference value and a poor prognosis of the survival time or a high risk of the recurrence of a myocardial infarction when the expression level is higher than the predetermined reference value.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 27, 2017
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite Paris Descartes, Universite Pierre et Marie Curie-UPMC, Assistance Publique-Hopitaux de Paris (APHP)
    Inventors: Ziad Mallat, Alain Tedgui, Tabassome Simon, Nicolas Danchin
  • Method and pharmaceutical composition for use in the treatment of cancer
    Patent number: 9198949
    Abstract: The present invention relates to a soluble peptide comprising the amino acids sequence: KRFYVVMWKK (SEQ ID NO: 1) or a function-conservative variant thereof for use in the treatment of cancer. The invention also relates to a pharmaceutical composition for use in the treatment of cancer comprising at least one soluble peptide according to the invention or at least one acid nucleic according to the invention or at least one expression vector according to the invention, or at least one host cell according to the invention and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: December 1, 2015
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE PIERRE ET MARIE CURIE UPMC, UNIVERSITE PARIS DIDEROT-PARIS 7, UNIVERSITE PARIS DESCARTES, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
    Inventors: Santos Susin, Pierre Launay, Philippe Karoyan, Helene Merle-Beral
  • ESTROGEN RECEPTOR ALPHA POLYPEPTIDE SEQUENCE, DIAGNOSTIC AND THERAPEUTIC APPLICATIONS THEREOF
    Publication number: 20130224285
    Abstract: The present invention presents new insights in the mechanism of action of the estrogen receptor alpha in breast cancer cells and provides means and tools for modulating said mechanisms of action, thereby influencing the proliferation of estrogen-positive cells such as cancer cells.
    Type: Application
    Filed: October 13, 2011
    Publication date: August 29, 2013
    Applicants: Universite Libre de Buxelles, UNIVERSITE PIERRE ET MARIE CURIE - UPMC, CNRS, UNIVERSITY OF CRETE - SCHOOL OF MEDICINE
    Inventors: Dominique Gallo, Guy LeClercq, Iman Haddad, Joelle Vinh, Elias Castanas, Marilena Kampa, Vasiliki Pelekanou, Yves Jacquot
  • Verotoxin B subunit for immunization
    Patent number: 8367071
    Abstract: Methods for stimulating an immune response in a mammal by administering a toxin-antigen conjugate are provided. Pharmaceutical compositions and methods for treating an antigen-related state are also described.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: February 5, 2013
    Assignees: Inserm-Transfert, Universite Pierre et Marie Curie (UPMC)
    Inventor: Allan M. Green
  • Chimeric polypeptide comprising the fragment B of shiga toxin and peptides of therapeutic interest
    Patent number: 7488809
    Abstract: The invention pertains to methods for using chimeric polypeptides of the formula: B—X wherein B represents the B fragment of Shiga toxin or a functional equivalent thereof, and X represents one or more polypeptides of therapeutic significance. Compositions for therapeutic use comprising the polypeptide B—X are also included.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: February 10, 2009
    Assignees: Insem-Transfert, Universite Pierre Et Marie Curie (UPMC)
    Inventors: Bruno Goud, Ludger Johannes